Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis

Ion channels in regulated cell death

(2016) Karl Kunzelmann   CELLULAR AND MOLECULAR LIFE SCIENCES

Cl− channels in apoptosis

(2016) Podchanart Wanitchakool et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage

(2016) Nadine J. A. Mattheij et al.   FASEB JOURNAL

Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis

(2015) Guoxing Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs

(2015) R. Planells-Cases et al.   EMBO JOURNAL

Unknown

(2015) Christian Hammer et al.   MOLECULAR MEDICINE

Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing

(2015) Lalida Sirianant et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

An Apoptotic ‘Eat Me’ Signal: Phosphatidylserine Exposure

(2015) Katsumori Segawa et al.   TRENDS IN CELL BIOLOGY

Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages

(2015) Jiraporn Ousingsawat et al.   Nature Communications

Identification of a lipid scrambling domain in ANO6/TMEM16F

(2015) Kuai Yu et al.   eLife

Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death

(2015) Jason Karch et al.   PLoS One

SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel

(2014) Zhaozhu Qiu et al.   CELL

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC

(2014) F. K. Voss et al.   SCIENCE

TMEM16F is a component of a Ca2+-activated Cl− channel but not a volume-sensitive outwardly rectifying Cl− channel

(2013) Takahiro Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Exploring Neural Cell Dynamics with Digital Holographic Microscopy

(2013) P. Marquet et al.   Annual Review of Biomedical Engineering

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

(2013) Xin Chen et al.   CELL RESEARCH

Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice

(2013) Eun-A Ko et al.   GUT

TMEM16F (Anoctamin 6), an anion channel of delayed Ca2+activation

(2013) Søren Grubb et al.   JOURNAL OF GENERAL PHYSIOLOGY

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

(2013) Zhenyu Cai et al.   NATURE CELL BIOLOGY

Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase?

(2013) Karl Kunzelmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

(2013) Stephen W.G. Tait et al.   Cell Reports

Anoctamins are a family of Ca2+-activated Cl- channels

(2012) Y. Tian et al.   JOURNAL OF CELL SCIENCE

Unknown

(2012) Andreas Linkermann et al.   MOLECULAR MEDICINE

Regulation of ENaC biogenesis by the stress response protein SERP1

(2012) Diana Faria et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Anoctamins

(2011) Karl Kunzelmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

(2010) Wan Namkung et al.   FASEB JOURNAL

Expression and Function of Epithelial Anoctamins

(2010) Rainer Schreiber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-invasive, label-free cell counting and quantitative analysis of adherent cells using digital holography

(2010) A. MÖLDER et al.   JOURNAL OF MICROSCOPY

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Cell Death by Necrosis, a Regulated Way to Go

(2008) Mauricio Henriquez et al.   CURRENT MOLECULAR MEDICINE