Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1

The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function

(2014) Diana Faria et al.   KIDNEY INTERNATIONAL

TMEM16F is a component of a Ca2+-activated Cl− channel but not a volume-sensitive outwardly rectifying Cl− channel

(2013) Takahiro Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Plasma membrane Ca2+ ATPase Atp2b1a regulates bone mineralization in zebrafish

(2013) William Go et al.   BONE

TMEM16F (Anoctamin 6), an anion channel of delayed Ca2+activation

(2013) Søren Grubb et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase?

(2013) Karl Kunzelmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Osteoblast CFTR Inactivation Reduces Differentiation and Osteoprotegerin Expression in a Mouse Model of Cystic Fibrosis-Related Bone Disease

(2013) Michael S. Stalvey et al.   PLoS One

Cystic fibrosis-related bone disease

(2013) Michael S. Stalvey et al.   Current Opinion in Endocrinology Diabetes and Obesity

Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity

(2013) M T Harper et al.   Cell Death & Disease

Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents

(2013) A Kmit et al.   Cell Death & Disease

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

(2013) Mattia Malvezzi et al.   Nature Communications

The F508del Mutation in Cystic Fibrosis Transmembrane Conductance Regulator Gene Impacts Bone Formation

(2012) Carole Le Henaff et al.   AMERICAN JOURNAL OF PATHOLOGY

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues

(2012) Harald WA Ehlen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Anoctamins are a family of Ca2+-activated Cl- channels

(2012) Y. Tian et al.   JOURNAL OF CELL SCIENCE

The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation

(2012) S. Boonrungsiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models with pathological mineralization phenotypes

(2011) Uwe Kornak   JOINT BONE SPINE

The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice

(2011) Bram C.J. van der Eerden et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bone mineralization proceeds through intracellular calcium phosphate loaded vesicles: A cryo-electron microscopy study

(2011) Julia Mahamid et al.   JOURNAL OF STRUCTURAL BIOLOGY

Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

(2010) Wan Namkung et al.   FASEB JOURNAL

TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

(2010) Wan Namkung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

The cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in maturation stage ameloblasts, odontoblasts and bone cells

(2009) Antonius Bronckers et al.   BONE

Calcification and silicification: a comparative survey of the early stages of biomineralization

(2009) Ermanno Bonucci   JOURNAL OF BONE AND MINERAL METABOLISM

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

Amorphous calcium phosphate is a major component of the forming fin bones of zebrafish: Indications for an amorphous precursor phase

(2008) J. Mahamid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE

NCX3 is a major functional isoform of the sodium–calcium exchanger in osteoblasts

(2007) Donna M. Sosnoski et al.   JOURNAL OF CELLULAR BIOCHEMISTRY