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Title
A New Venue of TNF Targeting
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 5, Pages 1442
Publisher
MDPI AG
Online
2018-05-14
DOI
10.3390/ijms19051442
References
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- TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE
- (2011) Niki Tsakiri et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity
- (2011) Xin Chen et al. FEBS LETTERS
- Antibodies Against Tumor Necrosis Factor (TNF) Induce T-Cell Apoptosis in Patients With Inflammatory Bowel Diseases via TNF Receptor 2 and Intestinal CD14+ Macrophages
- (2011) Raja Atreya et al. GASTROENTEROLOGY
- Inflammatory bowel disease therapies and cancer risk: where are we and where are we going?
- (2011) Laurent Beaugerie GUT
- Development of inflammatory bowel disease during anti-TNF-α therapy for inflammatory rheumatic disease. A nationwide series
- (2011) Éric Toussirot et al. JOINT BONE SPINE
- Novel TNF-α Receptor 1 Antagonist Treatment Attenuates Arterial Inflammation and Intimal Hyperplasia in Mice
- (2011) Manabu Kitagaki et al. Journal of Atherosclerosis and Thrombosis
- Targeting pre-ligand assembly domain of TNFR1 ameliorates autoimmune diseases – An unrevealed role in downregulation of Th17 cells
- (2011) Yen-Ling Wang et al. JOURNAL OF AUTOIMMUNITY
- Acute and delayed hypersensitivity reactions to infliximab and adalimumab in a patient with Crohn's disease
- (2011) Casper Steenholdt et al. Journal of Crohns & Colitis
- Pathogenic and Protective Functions of TNF in Neuroinflammation Are Defined by Its Expression in T Lymphocytes and Myeloid Cells
- (2011) A. A. Kruglov et al. JOURNAL OF IMMUNOLOGY
- Natural but Not Inducible Regulatory T Cells Require TNF- Signaling for In Vivo Function
- (2011) W. J. Housley et al. JOURNAL OF IMMUNOLOGY
- COGNITIVE IMPROVEMENT WITH INTRATHECAL ADMINISTRATION OF INFLIXIMAB IN A WOMAN WITH ALZHEIMER'S DISEASE
- (2011) Jian-Quan Shi et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
- (2011) Paramita Chakrabarty et al. Molecular Neurodegeneration
- A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death
- (2011) Roman Fischer et al. PLoS One
- Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
- (2011) M. Roulis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective inhibition of intra-alveolar p55 TNF receptor attenuates ventilator-induced lung injury
- (2011) Szabolcs Bertok et al. THORAX
- Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?
- (2011) Lien Dejager et al. TRENDS IN MICROBIOLOGY
- Human single-chain variable fragment that specifically targets arthritic cartilage
- (2010) Chris Hughes et al. ARTHRITIS AND RHEUMATISM
- Antiinflammatory effects of tumor necrosis factor on hematopoietic cells in a murine model of erosive arthritis
- (2010) Stephan Blüml et al. ARTHRITIS AND RHEUMATISM
- Cellular source and molecular form of TNF specify its distinct functions in organization of secondary lymphoid organs
- (2010) A. V. Tumanov et al. BLOOD
- Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains
- (2010) Jian-Quan Shi et al. BRAIN RESEARCH
- Enhand secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina ropria monouclear cells from patients with ulcretive cilitis and Crohn's disease
- (2010) H.-C. REINECKER et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Clinical development of onercept, a tumor necrosis factor binding protein, in psoriasis
- (2010) Kim Papp CURRENT MEDICAL RESEARCH AND OPINION
- Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood
- (2010) Xin Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice
- (2010) M. Chertoff et al. EXPERIMENTAL NEUROLOGY
- Golimumab as the first monthly subcutaneous fully human anti-TNF-α antibody in the treatment of inflammatory arthropathies
- (2010) Gabor Hutas Immunotherapy
- TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis
- (2010) Mario Noti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression of Costimulatory TNFR2 Induces Resistance of CD4+FoxP3- Conventional T Cells to Suppression by CD4+FoxP3+ Regulatory T Cells
- (2010) X. Chen et al. JOURNAL OF IMMUNOLOGY
- The value of failure: the discovery of TNF and its natural inhibitor erythropoietin
- (2010) A. Cerami JOURNAL OF INTERNAL MEDICINE
- Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways
- (2010) Caterina Veroni et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Wishing Away Inflammation? New Links between Serotonin and TNF Signaling
- (2010) M. Pelletier et al. MOLECULAR INTERVENTIONS
- TNF receptor 2 pathway: drug target for autoimmune diseases
- (2010) Denise Faustman et al. NATURE REVIEWS DRUG DISCOVERY
- Transmembrane TNF- : structure, function and interaction with anti-TNF agents
- (2010) T. Horiuchi et al. RHEUMATOLOGY
- TNF RECEPTOR 2, NOT TNF RECEPTOR 1, ENHANCES MESENCHYMAL STEM CELL-MEDIATED CARDIAC PROTECTION FOLLOWING ACUTE ISCHEMIA
- (2010) Megan L. Kelly et al. SHOCK
- A Variant of TNFR2-Fc Fusion Protein Exhibits Improved Efficacy in Treating Experimental Rheumatoid Arthritis
- (2010) Tong Yang et al. PLoS Computational Biology
- The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF
- (2009) Hiroko Shibata et al. BIOMATERIALS
- Decreased behavioral impairments in an Alzheimer mice model by interfering with TNF-alpha metabolism
- (2009) Fabienne Giuliani et al. BRAIN RESEARCH BULLETIN
- Tumor Necrosis Factor-α and Its Receptors 1 and 2
- (2009) Rainer Schulz et al. CIRCULATION
- Tumour Necrosis Factor Modulation for Treatment of Alzheimerʼs Disease
- (2009) Edward Tobinick CNS DRUGS
- Development of type 1 diabetes in a patient treated with anti-TNF-α therapy for active rheumatoid arthritis
- (2009) C. J. Tack et al. DIABETOLOGIA
- The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine
- (2009) L. G. Biesecker et al. GENOME RESEARCH
- Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice
- (2009) Tetsuya Nomura et al. JOURNAL OF CONTROLLED RELEASE
- Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis
- (2009) T. Secher et al. JOURNAL OF IMMUNOLOGY
- A Humanized Tumor Necrosis Factor Receptor 1 (TNFR1)-specific Antagonistic Antibody for Selective Inhibition of Tumor Necrosis Factor (TNF) Action
- (2009) Roland E. Kontermann et al. JOURNAL OF IMMUNOTHERAPY
- Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis
- (2009) K Vandenbroucke et al. Mucosal Immunology
- Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
- (2009) Philip L De Jager et al. NATURE GENETICS
- Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology
- (2009) Fiona E. McAlpine et al. NEUROBIOLOGY OF DISEASE
- Chronic expression of low levels of tumor necrosis factor-α in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation
- (2009) Ana Laura De Lella Ezcurra et al. NEUROBIOLOGY OF DISEASE
- Systemic inflammation and disease progression in Alzheimer disease
- (2009) C. Holmes et al. NEUROLOGY
- Molecular and functional interactions between tumor necrosis factor-alpha receptors and the glutamatergic system in the mouse hippocampus: Implications for seizure susceptibility
- (2009) S. Balosso et al. NEUROSCIENCE
- Anti-TNF-induced lupus
- (2009) E. L. Williams et al. RHEUMATOLOGY
- Predicting the future of anti-tumor necrosis factor therapy
- (2009) Cornelis L Verweij ARTHRITIS RESEARCH & THERAPY
- Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice
- (2008) Michelle C. Janelsins et al. AMERICAN JOURNAL OF PATHOLOGY
- Tumor Necrosis Factor α is Reparative via TNFR1 in the Hippocampus and via TNFR2 in the Striatum after Virus-Induced Encephalitis
- (2008) Moses Rodriguez et al. BRAIN PATHOLOGY
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- Regulatory T cells in inflammatory bowel disease
- (2008) Elisa K Boden et al. CURRENT OPINION IN GASTROENTEROLOGY
- Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
- (2008) Maria Armaka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration
- (2008) Edward L Tobinick et al. Journal of Neuroinflammation
- TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
- (2008) Melissa K McCoy et al. Journal of Neuroinflammation
- Serotonin 5-Hydroxytryptamine2A Receptor Activation Suppresses Tumor Necrosis Factor- -Induced Inflammation with Extraordinary Potency
- (2008) B. Yu et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats
- (2008) Melissa K McCoy et al. MOLECULAR THERAPY
- Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism
- (2008) L. Ban et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exogenous tumor necrosis factor-alpha induces suppression of autoimmune arthritis
- (2008) Eugene Y Kim et al. ARTHRITIS RESEARCH & THERAPY
- Restraining tumor necrosis factor-alpha by thalidomide prevents the Amyloid beta-induced impairment of recognition memory in mice
- (2007) Tursun Alkam et al. BEHAVIOURAL BRAIN RESEARCH
- TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1
- (2007) Jessy J. Alexander et al. NEUROCHEMISTRY INTERNATIONAL
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