Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

Mechanisms of tumor necrosis factor-alpha-induced leaks in intestine epithelial barrier

(2012) Fang He et al.   CYTOKINE

Mucosal permeability is an intrinsic factor in susceptibility to dextran sulfate sodium-induced colitis in rats

(2012) Hitoshi Iwaya et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Matrix Metalloprotease 8-Dependent Extracellular Matrix Cleavage at the Blood-CSF Barrier Contributes to Lethality during Systemic Inflammatory Diseases

(2012) R. E. Vandenbroucke et al.   JOURNAL OF NEUROSCIENCE

EMMPRIN Modulates Epithelial Barrier Function through a MMP–Mediated Occludin Cleavage

(2011) Eric Huet et al.   AMERICAN JOURNAL OF PATHOLOGY

Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis

(2011) Steven J. McElroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Epithelial Barriers in Intestinal Inflammation

(2011) Lena J. John et al.   ANTIOXIDANTS & REDOX SIGNALING

Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production

(2011) H Fukuda et al.   BRITISH JOURNAL OF CANCER

Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression

(2011) Eline Dejonckheere et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1

(2011) Filip Van Hauwermeiren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The first MMP in sepsis

(2011) Roosmarijn E. Vandenbroucke et al.   EMBO Molecular Medicine

A therapeutic role for matrix metalloproteinase inhibitors in lung diseases?

(2011) R. E. Vandenbroucke et al.   EUROPEAN RESPIRATORY JOURNAL

The unfolded protein response and its role in intestinal homeostasis and inflammation

(2011) Arthur Kaser et al.   EXPERIMENTAL CELL RESEARCH

Etanercept: efficacy and safety for approved indications

(2011) Todd A Kerensky et al.   Expert Opinion On Drug Safety

Matrix metalloproteinases: protective roles in cancer

(2011) Julie Decock et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways

(2011) Min Huan Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice

(2011) Sandra M Ocampo et al.   MOLECULAR THERAPY

Selecting protein N-terminal peptides by combined fractional diagonal chromatography

(2011) An Staes et al.   Nature Protocols

Mucin dynamics and enteric pathogens

(2011) Michael A. McGuckin et al.   NATURE REVIEWS MICROBIOLOGY

Tumor Necrosis Factor-α and Muc2 Mucin Play Major Roles in Disease Onset and Progression in Dextran Sodium Sulphate-Induced Colitis

(2011) Poonam Dharmani et al.   PLoS One

Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?

(2011) Lien Dejager et al.   TRENDS IN MICROBIOLOGY

Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases

(2010) Bénédicte Cauwe et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Matrix Metalloproteinases

(2010) O. Zitka et al.   CURRENT MEDICINAL CHEMISTRY

Matrix Metalloproteinase Inhibitors

(2010) György Dormán et al.   DRUGS

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

(2010) Amanda M. Marchiando et al.   JOURNAL OF CELL BIOLOGY

ms_lims, a simple yet powerful open source laboratory information management system for MS-driven proteomics

(2010) Kenny Helsens et al.   PROTEOMICS

Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis

(2010) Timo Rath et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Effect of a matrix metalloproteinase sequestering biomaterial on Caco-2 epithelial cell barrier integrity in vitro

(2009) Menachem Ailenberg et al.   Acta Biomaterialia

Differential regulation of MMP-13 expression in two models of experimentally induced periodontal disease in rats

(2009) Sabrina Garcia de Aquino et al.   ARCHIVES OF ORAL BIOLOGY

Matrix Metalloproteinases as Drug Targets in Infections Caused by Gram-Negative Bacteria and in Septic Shock

(2009) I. Vanlaere et al.   CLINICAL MICROBIOLOGY REVIEWS

Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock

(2009) Dinna N. Cruz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hypoxia-induced matrix metalloproteinase-13 expression in astrocytes enhances permeability of brain endothelial cells

(2009) Dah-Yuu Lu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Disruption of tight junctions during polymicrobial sepsisin vivo

(2009) Qiurong Li et al.   JOURNAL OF PATHOLOGY

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

Host immune response to antibiotic perturbation of the microbiota

(2009) M Wlodarska et al.   Mucosal Immunology

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Temporal and Spatial Analysis of Clinical and Molecular Parameters in Dextran Sodium Sulfate Induced Colitis

(2009) Yutao Yan et al.   PLoS One

Joint Diseases and Matrix Metalloproteinases: A Role for MMP-13

(2008) Hironari Takaishi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors

(2008) Vincenzo Cantaluppi et al.   INTENSIVE CARE MEDICINE

Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis

(2008) Chad K Heazlewood et al.   PLOS MEDICINE