Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice

Title
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice
Authors
Keywords
Neuroinflammation, Alzheimer's disease, Immune cell trafficking, T cells, Macrophage, MHCII, Soluble TNF, Long-term potentiation, XPro1595
Journal
NEUROBIOLOGY OF DISEASE
Volume 102, Issue -, Pages 81-95
Publisher
Elsevier BV
Online
2017-02-25
DOI
10.1016/j.nbd.2017.02.010

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