Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

Lovastatin Induces Neuroprotection Through Tumor Necrosis Factor Receptor 2 Signaling Pathways

(2017) Amalia M. Dolga et al.   JOURNAL OF ALZHEIMERS DISEASE

Astrocyte TNFR2 is required for CXCL12-mediated regulation of oligodendrocyte progenitor proliferation and differentiation within the adult CNS

(2012) Jigisha R. Patel et al.   ACTA NEUROPATHOLOGICA

Preclinical Retinal Neurodegeneration in a Model of Multiple Sclerosis

(2012) R. Fairless et al.   JOURNAL OF NEUROSCIENCE

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

(2012) Adam P. Gregory et al.   NATURE

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

(2011) Roberta Brambilla et al.   BRAIN

Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-κB

(2011) Era Taoufik et al.   BRAIN

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1

(2011) Filip Van Hauwermeiren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Novel TNF-α Receptor 1 Antagonist Treatment Attenuates Arterial Inflammation and Intimal Hyperplasia in Mice

(2011) Manabu Kitagaki et al.   Journal of Atherosclerosis and Thrombosis

Targeting pre-ligand assembly domain of TNFR1 ameliorates autoimmune diseases – An unrevealed role in downregulation of Th17 cells

(2011) Yen-Ling Wang et al.   JOURNAL OF AUTOIMMUNITY

Tumor necrosis factor alpha (TNF-α), anti-TNF-α and demyelination revisited: An ongoing story

(2011) Ana Caminero et al.   JOURNAL OF NEUROIMMUNOLOGY

A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death

(2011) Roman Fischer et al.   PLoS One

Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways

(2010) Caterina Veroni et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice

(2009) Tetsuya Nomura et al.   JOURNAL OF CONTROLLED RELEASE

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation