- Home
- Publications
- Publication Search
- Publication Details
Title
Convergent Mechanisms Underlying Rapid Antidepressant Action
Authors
Keywords
-
Journal
CNS DRUGS
Volume 32, Issue 3, Pages 197-227
Publisher
Springer Nature
Online
2018-03-07
DOI
10.1007/s40263-018-0492-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis
- (2018) Samuel T. Wilkinson et al. AMERICAN JOURNAL OF PSYCHIATRY
- Common Neurotransmission Recruited in ( R , S )-Ketamine and (2 R ,6 R )-Hydroxynorketamine–Induced Sustained Antidepressant-like Effects
- (2018) Thu Ha Pham et al. BIOLOGICAL PSYCHIATRY
- Intracellular Signaling Pathways Involved in ( S )- and ( R )-Ketamine Antidepressant Actions
- (2018) Panos Zanos et al. BIOLOGICAL PSYCHIATRY
- Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of Scopolamine
- (2018) Sriparna Ghosal et al. BIOLOGICAL PSYCHIATRY
- Mechanisms of ketamine action as an antidepressant
- (2018) P Zanos et al. MOLECULAR PSYCHIATRY
- Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice
- (2018) Nina Z. Xu et al. PSYCHOPHARMACOLOGY
- Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression
- (2018) Ella J. Daly et al. JAMA Psychiatry
- Ketamine blocks bursting in the lateral habenula to rapidly relieve depression
- (2018) Yan Yang et al. NATURE
- History of anaesthesia
- (2017) Georges Mion EUROPEAN JOURNAL OF ANAESTHESIOLOGY
- Selective Pharmacological Augmentation of Hippocampal Activity Produces a Sustained Antidepressant-Like Response without Abuse-Related or Psychotomimetic Effects
- (2017) Flavia R. Carreno et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine
- (2017) Yukihiko Shirayama et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Antidepressant Potential of ( R )-Ketamine in Rodent Models: Comparison with ( S )-Ketamine
- (2017) Kenichi Fukumoto et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit
- (2017) N Yao et al. MOLECULAR PSYCHIATRY
- Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects
- (2017) S-X Li et al. MOLECULAR PSYCHIATRY
- Identification of a novel, fast-acting GABAergic antidepressant
- (2017) K M J McMurray et al. MOLECULAR PSYCHIATRY
- Identifying fast-onset antidepressants using rodent models
- (2017) M J Ramaker et al. MOLECULAR PSYCHIATRY
- Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling
- (2017) L Cavalleri et al. MOLECULAR PSYCHIATRY
- Neuronal plasticity and neurotrophic factors in drug responses
- (2017) E Castrén et al. MOLECULAR PSYCHIATRY
- BDNF release and signaling are required for the antidepressant actions of GLYX-13
- (2017) T Kato et al. MOLECULAR PSYCHIATRY
- Zanos et al. reply
- (2017) Panos Zanos et al. NATURE
- Effects of a ketamine metabolite on synaptic NMDAR function
- (2017) Kanzo Suzuki et al. NATURE
- Targeting glutamate signalling in depression: progress and prospects
- (2017) James W. Murrough et al. NATURE REVIEWS DRUG DISCOVERY
- Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites
- (2017) Patrick J. Morris et al. ORGANIC LETTERS
- A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders
- (2017) Gerard Sanacora et al. JAMA Psychiatry
- Possible role of the gut microbiota–brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model
- (2017) Chun Yang et al. Translational Psychiatry
- Animal models to improve our understanding and treatment of suicidal behavior
- (2017) T D Gould et al. Translational Psychiatry
- Isoflurane produces antidepressant effects and induces TrkB signaling in rodents
- (2017) Hanna Antila et al. Scientific Reports
- A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression
- (2016) Jaskaran B. Singh et al. AMERICAN JOURNAL OF PSYCHIATRY
- Short-term sleep deprivation disrupts the molecular composition of ionotropic glutamate receptors in entorhinal cortex and impairs the rat spatial reference memory
- (2016) Meilan Xie et al. BEHAVIOURAL BRAIN RESEARCH
- GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice
- (2016) Lakshmi Rajagopal et al. BEHAVIOURAL BRAIN RESEARCH
- Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress–Induced Depressive Behaviors
- (2016) Ja Wook Koo et al. BIOLOGICAL PSYCHIATRY
- Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior
- (2016) Rebecca A. Brachman et al. BIOLOGICAL PSYCHIATRY
- Bidirectional Homeostatic Regulation of a Depression-Related Brain State by Gamma-Aminobutyric Acidergic Deficits and Ketamine Treatment
- (2016) Zhen Ren et al. BIOLOGICAL PSYCHIATRY
- Intravenous Esketamine in Adult Treatment-Resistant Depression: A Double-Blind, Double-Randomization, Placebo-Controlled Study
- (2016) Jaskaran B. Singh et al. BIOLOGICAL PSYCHIATRY
- Sex Differences in Effects of Ketamine on Behavior, Spine Density, and Synaptic Proteins in Socially Isolated Rats
- (2016) Ambalika Sarkar et al. BIOLOGICAL PSYCHIATRY
- Ketamine-induced inhibition of glycogen synthase kinase-3 contributes to the augmentation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor signaling
- (2016) Eléonore Beurel et al. BIPOLAR DISORDERS
- Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine
- (2016) Eric Wohleb et al. Current Neuropharmacology
- GABA interneurons mediate the rapid antidepressant-like effects of scopolamine
- (2016) Eric S. Wohleb et al. JOURNAL OF CLINICAL INVESTIGATION
- Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state
- (2016) T Fuchs et al. MOLECULAR PSYCHIATRY
- Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects
- (2016) G M I Chowdhury et al. MOLECULAR PSYCHIATRY
- NMDAR inhibition-independent antidepressant actions of ketamine metabolites
- (2016) Panos Zanos et al. NATURE
- Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
- (2016) Ronald S Duman et al. NATURE MEDICINE
- Synaptic AMPA receptor composition in development, plasticity and disease
- (2016) Jeremy M. Henley et al. NATURE REVIEWS NEUROSCIENCE
- Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study
- (2016) Gerard Sanacora et al. NEUROPSYCHOPHARMACOLOGY
- GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine
- (2016) Rong-Jian Liu et al. NEUROPSYCHOPHARMACOLOGY
- Phosphodiesterase 10A inhibition attenuates sleep deprivation-induced deficits in long-term fear memory
- (2016) Lengqiu Guo et al. NEUROSCIENCE LETTERS
- Single-dose infusion ketamine and non-ketamine N-methyl-d-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories
- (2016) T. Kishimoto et al. PSYCHOLOGICAL MEDICINE
- Rapamycin blocks the antidepressant effect of ketamine in task-dependent manner
- (2016) Kristina Holubova et al. PSYCHOPHARMACOLOGY
- Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression
- (2016) Bangkun Yang et al. PSYCHOPHARMACOLOGY
- Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine
- (2016) K. Zhang et al. Science Signaling
- What Are We Learning From Early-Phase Clinical Trials With Glutamate Targeting Medications for the Treatment of Major Depressive Disorder
- (2016) Gerard Sanacora JAMA Psychiatry
- Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine
- (2016) K. Zhang et al. Science Signaling
- Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator
- (2016) Sean C. Piantadosi et al. Frontiers in Pharmacology
- Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression
- (2015) D. Jeffrey Newport et al. AMERICAN JOURNAL OF PSYCHIATRY
- Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: Characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats
- (2015) Jeffrey Burgdorf et al. BEHAVIOURAL BRAIN RESEARCH
- Short-term sleep deprivation impairs spatial working memory and modulates expression levels of ionotropic glutamate receptor subunits in hippocampus
- (2015) Meilan Xie et al. BEHAVIOURAL BRAIN RESEARCH
- NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism
- (2015) Carly Kiselycznyk et al. BEHAVIOURAL BRAIN RESEARCH
- Sex-dependent modulation of age-related cognitive decline by the L-type calcium channel geneCacna1c(Cav1.2)
- (2015) Panos Zanos et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Ketamine-like effects of a combination of olanzapine and fluoxetine on AMPA and NMDA receptor-mediated transmission in the medial prefrontal cortex of the rat
- (2015) Carl Björkholm et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- P.2.f.021 Results of a double-blind placebo-controlled study of the antidepressant effects of the mGLU2 negative allosteric modulator RG1578
- (2015) D. Umbricht et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- PI3K/AKT/mTOR Signaling-Mediated Neuropeptide VGF in the Hippocampus of Mice Is Involved in the Rapid Onset Antidepressant-Like Effects of GLYX-13
- (2015) Yang Lu et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Evidence that Subanesthetic Doses of Ketamine Cause Sustained Disruptions of NMDA and AMPA-Mediated Frontoparietal Connectivity in Humans
- (2015) Suresh D. Muthukumaraswamy et al. JOURNAL OF NEUROSCIENCE
- Randomized Proof of Concept Trial of GLYX-13, an N-Methyl-D-Aspartate Receptor Glycine Site Partial Agonist, in Major Depressive Disorder Nonresponsive to a Previous Antidepressant Agent
- (2015) SHELDON PRESKORN et al. Journal of Psychiatric Practice
- Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons
- (2015) Kareem S El Iskandrani et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors
- (2015) Andrea Navarria et al. NEUROBIOLOGY OF DISEASE
- Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors
- (2015) Jonathan Fischell et al. NEUROPSYCHOPHARMACOLOGY
- The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus
- (2015) J. Burgdorf et al. NEUROSCIENCE
- Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
- (2015) Eleonore Beurel et al. PHARMACOLOGY & THERAPEUTICS
- Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions
- (2015) Manabu Fuchikami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Behavioral and molecular responses to electroconvulsive shock differ between genetic and environmental rat models of depression
- (2015) Jie Luo et al. PSYCHIATRY RESEARCH
- Meta-analysis of short- and mid-term efficacy of ketamine in unipolar and bipolar depression
- (2015) Bruno Romeo et al. PSYCHIATRY RESEARCH
- Single i.v. ketamine augmentation of newly initiated escitalopram for major depression: results from a randomized, placebo-controlled 4-week study
- (2015) Y.-D. Hu et al. PSYCHOLOGICAL MEDICINE
- Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression
- (2015) Ji-chun Zhang et al. PSYCHOPHARMACOLOGY
- An excitatory synapse hypothesis of depression
- (2015) Scott M. Thompson et al. TRENDS IN NEUROSCIENCES
- R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects
- (2015) C Yang et al. Translational Psychiatry
- BDNF Release Is Required for the Behavioral Actions of Ketamine
- (2015) A. E. Lepack et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- (R,S)-Ketamine Metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine Increase the Mammalian Target of Rapamycin Function
- (2014) Rajib K. Paul et al. ANESTHESIOLOGY
- Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats
- (2014) Hiroyuki Koike et al. BEHAVIOURAL BRAIN RESEARCH
- Blockade of the metabotropic glutamate (mGluR2) modulates arousal through vigilance states transitions: Evidence from sleep–wake EEG in rodents
- (2014) A. Ahnaou et al. BEHAVIOURAL BRAIN RESEARCH
- Restoring Mood Balance in Depression: Ketamine Reverses Deficit in Dopamine-Dependent Synaptic Plasticity
- (2014) Pauline Belujon et al. BIOLOGICAL PSYCHIATRY
- A Randomized Controlled Trial of Intranasal Ketamine in Major Depressive Disorder
- (2014) Kyle A.B. Lapidus et al. BIOLOGICAL PSYCHIATRY
- Effects of Striatal ΔFosB Overexpression and Ketamine on Social Defeat Stress–Induced Anhedonia in Mice
- (2014) Rachel J. Donahue et al. BIOLOGICAL PSYCHIATRY
- Acupuncture stimulation improves scopolamine-induced cognitive impairment via activation of cholinergic system and regulation of BDNF and CREB expressions in rats
- (2014) Bombi Lee et al. BMC Complementary and Alternative Medicine
- EFFECTS OF KETAMINE ON EXPLICIT AND IMPLICIT SUICIDAL COGNITION: A RANDOMIZED CONTROLLED TRIAL IN TREATMENT-RESISTANT DEPRESSION
- (2014) Rebecca B. Price et al. DEPRESSION AND ANXIETY
- Effects of aberrant gamma frequency oscillations on prepulse inhibition
- (2014) Nigel C. Jones et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Improvement in suicidal ideation after ketamine infusion: Relationship to reductions in depression and anxiety
- (2014) Elizabeth D. Ballard et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Akt Mediates GSK-3� Phosphorylation in the Rat Prefrontal Cortex during the Process of Ketamine Exerting Rapid Antidepressant Actions
- (2014) Wei Zhou et al. NEUROIMMUNOMODULATION
- Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function
- (2014) Yukitoshi Izumi et al. NEUROPHARMACOLOGY
- The Role of GluN2A and GluN2B Subunits on the Effects of NMDA Receptor Antagonists in Modeling Schizophrenia and Treating Refractory Depression
- (2014) Laura Jiménez-Sánchez et al. NEUROPSYCHOPHARMACOLOGY
- Involvement of glutamatergic and GABAergic transmission in MK-801-increased gamma band oscillation power in rat cortical electroencephalograms
- (2014) T. Hiyoshi et al. NEUROSCIENCE
- Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test
- (2014) Małgorzata Wolak et al. Pharmacological Reports
- Molecular actions and clinical pharmacogenetics of lithium therapy
- (2014) Adem Can et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Lycium barbarum Polysaccharides Prevent Memory and Neurogenesis Impairments in Scopolamine-Treated Rats
- (2014) Weiwei Chen et al. PLoS One
- Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses
- (2014) E. S. Gideons et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The STAR*D Trial: Revealing the Need for Better Treatments
- (2014) Thomas R. Insel et al. PSYCHIATRIC SERVICES
- A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials of ketamine in the rapid treatment of major depressive episodes
- (2014) A. McGirr et al. PSYCHOLOGICAL MEDICINE
- 7-Chlorokynurenic acid (7-CTKA) produces rapid antidepressant-like effects: through regulating hippocampal microRNA expressions involved in TrkB-ERK/Akt signaling pathways in mice exposed to chronic unpredictable mild stress
- (2014) Bin-Bin Liu et al. PSYCHOPHARMACOLOGY
- Serotonin-1A receptor stimulation mediates effects of a metabotropic glutamate 2/3 receptor antagonist, 2S-2-amino-2-(1S,2S-2-carboxycycloprop-1-yl)-3-(xanth-9-yl)propanoic acid (LY341495), and an N-methyl-D-aspartate receptor antagonist, ketamine, in the novelty-suppressed feeding test
- (2014) Kenichi Fukumoto et al. PSYCHOPHARMACOLOGY
- Sleep deprivation induces differential morphological changes in the hippocampus and prefrontal cortex in young and old rats
- (2014) Eva Acosta-peña et al. SYNAPSE
- Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression
- (2014) N Lally et al. Translational Psychiatry
- Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial
- (2013) James W. Murrough et al. AMERICAN JOURNAL OF PSYCHIATRY
- Human Biomarkers of Rapid Antidepressant Effects
- (2013) Carlos A. Zarate et al. BIOLOGICAL PSYCHIATRY
- Scopolamine Rapidly Increases Mammalian Target of Rapamycin Complex 1 Signaling, Synaptogenesis, and Antidepressant Behavioral Responses
- (2013) Bhavya Voleti et al. BIOLOGICAL PSYCHIATRY
- Inhibition of Glycine Transporter-I as a Novel Mechanism for the Treatment of Depression
- (2013) Chih-Chia Huang et al. BIOLOGICAL PSYCHIATRY
- Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings)
- (2013) Georges Mion et al. CNS Neuroscience & Therapeutics
- Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex
- (2013) W. Zhou et al. EUROPEAN PSYCHIATRY
- GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists
- (2013) Joseph R Moskal et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Antidepressant Augmentation Using theN-Methyl-d-Aspartate Antagonist Memantine
- (2013) Eric G. Smith et al. JOURNAL OF CLINICAL PSYCHIATRY
- Expression of m1-type muscarinic acetylcholine receptors by parvalbumin-immunoreactive neurons in the primary visual cortex: A comparative study of rat, guinea pig, ferret, macaque, and human
- (2013) Anita A. Disney et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Effects of Acute and Chronic Electroconvulsive Shocks on Glycogen Synthase Kinase 3β Level and Phosphorylation in Mice
- (2013) Koray Basar et al. JOURNAL OF ECT
- Acute Suppression of Spontaneous Neurotransmission Drives Synaptic Potentiation
- (2013) E. Nosyreva et al. JOURNAL OF NEUROSCIENCE
- Cortical Control of Affective Networks
- (2013) S. Kumar et al. JOURNAL OF NEUROSCIENCE
- Chronic Stress Induces a Selective Decrease in AMPA Receptor-Mediated Synaptic Excitation at Hippocampal Temporoammonic-CA1 Synapses
- (2013) A. J. Kallarackal et al. JOURNAL OF NEUROSCIENCE
- Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats
- (2013) Wei-Li Zhu et al. JOURNAL OF PSYCHIATRY & NEUROSCIENCE
- Rapid antidepressant effects: moving right along
- (2013) K Martinowich et al. MOLECULAR PSYCHIATRY
- Serotonin 2C receptor antagonists induce fast-onset antidepressant effects
- (2013) M D Opal et al. MOLECULAR PSYCHIATRY
- Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects
- (2013) G Sanacora et al. MOLECULAR PSYCHIATRY
- Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression
- (2013) Xiang Cai et al. NATURE NEUROSCIENCE
- The role of eEF2 pathway in learning and synaptic plasticity
- (2013) Elham Taha et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Sex differences in the antidepressant-like effects of ketamine
- (2013) Nicole Carrier et al. NEUROPHARMACOLOGY
- GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects
- (2013) Jeffrey Burgdorf et al. NEUROPSYCHOPHARMACOLOGY
- GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine
- (2013) Rong-Jian Liu et al. NEUROPSYCHOPHARMACOLOGY
- NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice
- (2013) Adam K Walker et al. NEUROPSYCHOPHARMACOLOGY
- R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine
- (2013) Ji-chun Zhang et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Antidepressant and Neurocognitive Effects of Isoflurane Anesthesia versus Electroconvulsive Therapy in Refractory Depression
- (2013) Howard R. Weeks et al. PLoS One
- Chronic scopolamine-injection-induced cognitive deficit on reward-directed instrumental learning in rat is associated with CREB signaling activity in the cerebral cortex and dorsal hippocampus
- (2013) Zhe Shi et al. PSYCHOPHARMACOLOGY
- Antidepressant effects of AMPA and ketamine combination: role of hippocampal BDNF, synapsin, and mTOR
- (2013) Luli Akinfiresoye et al. PSYCHOPHARMACOLOGY
- Knockdown of BNST GluN2B-containing NMDA receptors mimics the actions of ketamine on novelty-induced hypophagia
- (2013) K M Louderback et al. Translational Psychiatry
- Mechanisms of Gamma Oscillations
- (2012) György Buzsáki et al. Annual Review of Neuroscience
- Post-transcriptional effects and interactions between chronic mild stress and acute sleep deprivation: Regulation of translation factor and cytoplasmic polyadenylation element-binding protein phosphorylation
- (2012) Janne Grønli et al. BEHAVIOURAL BRAIN RESEARCH
- Acute and sustained effects of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test
- (2012) Michihiko Iijima et al. BEHAVIOURAL BRAIN RESEARCH
- Role of BDNF/TrkB signaling in antidepressant-like effects of a group II metabotropic glutamate receptor antagonist in animal models of depression
- (2012) Hiroyuki Koike et al. BEHAVIOURAL BRAIN RESEARCH
- Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Antidepressant Efficacy of Ketamine in Depressed Patients
- (2012) Gonzalo Laje et al. BIOLOGICAL PSYCHIATRY
- Relationship of Ketamine's Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression
- (2012) Carlos A. Zarate et al. BIOLOGICAL PSYCHIATRY
- Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial
- (2012) Carlos A. Zarate et al. BIOLOGICAL PSYCHIATRY
- Efficacy of electroconvulsive therapy in bipolar versus unipolar major depression: a meta-analysis
- (2012) Bram Dierckx et al. BIPOLAR DISORDERS
- Long-term potentiation and long-term depression: a clinical perspective
- (2012) Timothy V.P. Bliss et al. Clinics
- Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors
- (2012) Ruin Moaddel et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- A randomized add-on trial of high-dose d-cycloserine for treatment-resistant depression
- (2012) Uriel Heresco-Levy et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal
- (2012) Margaret G. Distler et al. JOURNAL OF CLINICAL INVESTIGATION
- A Randomized, Placebo-Controlled, Crossover Pilot Trial of the Oral Selective NR2B Antagonist MK-0657 in Patients With Treatment-Resistant Major Depressive Disorder
- (2012) Lobna Ibrahim et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- The BDNF Val66Met Polymorphism Impairs Synaptic Transmission and Plasticity in the Infralimbic Medial Prefrontal Cortex
- (2012) S. S. Pattwell et al. JOURNAL OF NEUROSCIENCE
- Diagnostic accuracy of serum brain derived neurotrophic factor concentration in antidepressant naïve patients with first major depression episode
- (2012) Dalibor Karlović et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Phosphorylation of Eukaryotic Elongation Factor 2 (eEF2) by Cyclin A–Cyclin-Dependent Kinase 2 Regulates Its Inhibition by eEF2 Kinase
- (2012) Asli A. Hizli et al. MOLECULAR AND CELLULAR BIOLOGY
- Decreased expression of synapse-related genes and loss of synapses in major depressive disorder
- (2012) Hyo Jung Kang et al. NATURE MEDICINE
- Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice
- (2012) Yukio Ago et al. NEUROPHARMACOLOGY
- Stress, anxiety, and dendritic spines: What are the connections?
- (2012) B. Leuner et al. NEUROSCIENCE
- Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder
- (2012) Taisuke Yoshida et al. PLoS One
- Synaptic Dysfunction in Depression: Potential Therapeutic Targets
- (2012) R. S. Duman et al. SCIENCE
- State-Dependent Increase of Cortical Gamma Activity during REM Sleep after Selective Blockade of NR2B Subunit Containing NMDA Receptors
- (2012) Bernat Kocsis SLEEP
- Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test
- (2012) Chun Yang et al. UPSALA JOURNAL OF MEDICAL SCIENCES
- Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression
- (2011) Hiroyuki Koike et al. BEHAVIOURAL BRAIN RESEARCH
- Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
- (2011) Nanxin Li et al. BIOLOGICAL PSYCHIATRY
- Differential Role of NR2A and NR2B Subunits in N-Methyl-D-Aspartate Receptor Antagonist-Induced Aberrant Cortical Gamma Oscillations
- (2011) Bernat Kocsis BIOLOGICAL PSYCHIATRY
- Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex
- (2011) Rong-Jian Liu et al. BIOLOGICAL PSYCHIATRY
- Memantine for late-life depression and apathy after a disabling medical event: a 12-week, double-blind placebo-controlled pilot study
- (2011) Eric J. Lenze et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- mTOR activation is required for the antidepressant effects of mGluR2/3 blockade
- (2011) Jason M. Dwyer et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- A complex interaction between glycine/NMDA receptors and serotonergic/noradrenergic antidepressants in the forced swim test in mice
- (2011) Ewa Poleszak et al. JOURNAL OF NEURAL TRANSMISSION
- Resilience to Chronic Stress Is Mediated by Hippocampal Brain-Derived Neurotrophic Factor
- (2011) D. Taliaz et al. JOURNAL OF NEUROSCIENCE
- Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice
- (2011) E Beurel et al. MOLECULAR PSYCHIATRY
- NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
- (2011) Anita E. Autry et al. NATURE
- Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists
- (2011) Hiroyuki Koike et al. NEUROPHARMACOLOGY
- The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf+/− heterozygous null mice
- (2011) Jesse S.O. Lindholm et al. NEUROPHARMACOLOGY
- Signaling pathways underlying the rapid antidepressant actions of ketamine
- (2011) Ronald S. Duman et al. NEUROPHARMACOLOGY
- Anxiety and depression: Mouse genetics and pharmacological approaches to the role of GABAA receptor subtypes
- (2011) Kiersten S. Smith et al. NEUROPHARMACOLOGY
- The GABA system in anxiety and depression and its therapeutic potential
- (2011) Hanns Möhler NEUROPHARMACOLOGY
- Protective Role of Ashwagandha Leaf Extract and Its Component Withanone on Scopolamine-Induced Changes in the Brain and Brain-Derived Cells
- (2011) Arpita Konar et al. PLoS One
- A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression
- (2010) Nancy Diazgranados et al. ARCHIVES OF GENERAL PSYCHIATRY
- γ-Aminobutyric Acid-Type A Receptor Deficits Cause Hypothalamic-Pituitary-Adrenal Axis Hyperactivity and Antidepressant Drug Sensitivity Reminiscent of Melancholic Forms of Depression
- (2010) Qiuying Shen et al. BIOLOGICAL PSYCHIATRY
- Replication of Scopolamine's Antidepressant Efficacy in Major Depressive Disorder: A Randomized, Placebo-Controlled Clinical Trial
- (2010) Wayne C. Drevets et al. BIOLOGICAL PSYCHIATRY
- Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder
- (2010) Nancy DiazGranados et al. JOURNAL OF CLINICAL PSYCHIATRY
- A Post Hoc Analysis of the Effect of Nightly Administration of Eszopiclone and a Selective Serotonin Reuptake Inhibitor in Patients With Insomnia and Anxious Depression
- (2010) Maurizio Fava et al. JOURNAL OF CLINICAL PSYCHIATRY
- Rapid microelectrode measurements and the origin and regulation of extracellular glutamate in rat prefrontal cortex
- (2010) Erin R. Hascup et al. JOURNAL OF NEUROCHEMISTRY
- Serum levels of brain-derived neurotrophic factor in major depressive disorder: state–trait issues, clinical features and pharmacological treatment
- (2010) M L Molendijk et al. MOLECULAR PSYCHIATRY
- Scopolamine Produces Larger Antidepressant and Antianxiety Effects in Women Than in Men
- (2010) Maura L Furey et al. NEUROPSYCHOPHARMACOLOGY
- Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models
- (2010) Heath D Schmidt et al. NEUROPSYCHOPHARMACOLOGY
- Blockade of different muscarinic receptor subtypes changes the equilibrium between excitation and inhibition in rat visual cortex
- (2010) M. Amar et al. NEUROSCIENCE
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
- (2010) N. Li et al. SCIENCE
- Serum and plasma BDNF levels in major depression: A replication study and meta-analyses
- (2010) Luisella Bocchio-Chiavetto et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Site-Specific Antidepressant Effects of Repeated Subconvulsive Electrical Stimulation: Potential Role of Brain-Derived Neurotrophic Factor
- (2009) Roman Gersner et al. BIOLOGICAL PSYCHIATRY
- Reduced parahippocampal and lateral temporal GABAA-[11C]flumazenil binding in major depression: preliminary results
- (2009) Ursula M. H. Klumpers et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- The Sigma Enigma: Can Sigma Receptors Provide a Novel Target for Disorders of Mood and Cognition?
- (2009) Stephen M. Stahl JOURNAL OF CLINICAL PSYCHIATRY
- Comments on "An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-d-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder"
- (2009) Kenji Hashimoto JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Ketamine Modulates Theta and Gamma Oscillations
- (2009) Maciej T. Lazarewicz et al. JOURNAL OF COGNITIVE NEUROSCIENCE
- In Vitro and in Vivo Properties of 3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA Receptor 5 Subtype-Selective Inverse Agonist
- (2009) J. R. Atack et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The Antidepressant Effects of Anticholinergic Drugs
- (2009) Robert H. Howland JOURNAL OF PSYCHOSOCIAL NURSING AND MENTAL HEALTH SERVICES
- Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
- (2009) Vikaas S. Sohal et al. NATURE
- Driving fast-spiking cells induces gamma rhythm and controls sensory responses
- (2009) Jessica A. Cardin et al. NATURE
- The N-methyl-d-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats
- (2009) Jeffrey Burgdorf et al. NEUROBIOLOGY OF AGING
- Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery
- (2009) D.S. Goldwater et al. NEUROSCIENCE
- Correlations and Discrepancies between Serum and Brain Tissue Levels of Neurotrophins after Electroconvulsive Treatment in Rats
- (2009) A. Sartorius et al. PHARMACOPSYCHIATRY
- mTOR signaling: At the crossroads of plasticity, memory and disease
- (2009) Charles A. Hoeffer et al. TRENDS IN NEUROSCIENCES
- Augmentation of Behavior Therapy Withd-Cycloserine for Obsessive-Compulsive Disorder
- (2008) Sabine Wilhelm et al. AMERICAN JOURNAL OF PSYCHIATRY
- Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments
- (2008) Darrick T. Balu et al. BRAIN RESEARCH
- Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis
- (2008) Sadaharu Kotani et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression
- (2008) Anton Y. Bespalov et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder
- (2008) Sheldon H. Preskorn et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling
- (2008) J M Bessa et al. MOLECULAR PSYCHIATRY
- Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD
- (2008) Sungjin Park et al. NEURON
- A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral–CA1 synapses in hippocampus
- (2008) Xiao-lei Zhang et al. NEUROPHARMACOLOGY
- A Randomized, Placebo-Controlled Study of Memantine as Adjunctive Treatment in Patients with Schizophrenia
- (2008) Jeffrey A Lieberman et al. NEUROPSYCHOPHARMACOLOGY
- Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy
- (2007) Megumi Adachi et al. BIOLOGICAL PSYCHIATRY
- Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors
- (2007) Sungho Maeng et al. BIOLOGICAL PSYCHIATRY
- Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
- (2007) Lêda S.B. Garcia et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More