Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit
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Title
Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit
Authors
Keywords
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Journal
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2017-11-21
DOI
10.1038/mp.2017.239
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Note: Only part of the references are listed.- Ketamine: translating mechanistic discoveries into the next generation of glutamate modulators for mood disorders
- (2017) C A Zarate et al. MOLECULAR PSYCHIATRY
- Ventral tegmental area: cellular heterogeneity, connectivity and behaviour
- (2017) Marisela Morales et al. NATURE REVIEWS NEUROSCIENCE
- The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder
- (2017) Chadi G Abdallah et al. NEUROPSYCHOPHARMACOLOGY
- Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress–Induced Depressive Behaviors
- (2016) Ja Wook Koo et al. BIOLOGICAL PSYCHIATRY
- Intravenous Esketamine in Adult Treatment-Resistant Depression: A Double-Blind, Double-Randomization, Placebo-Controlled Study
- (2016) Jaskaran B. Singh et al. BIOLOGICAL PSYCHIATRY
- GSK-3: A key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced AMPA to NMDA throughput
- (2016) Carlos A Zarate et al. BIPOLAR DISORDERS
- KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS
- (2016) Chadi G. Abdallah et al. DEPRESSION AND ANXIETY
- NMDAR inhibition-independent antidepressant actions of ketamine metabolites
- (2016) Panos Zanos et al. NATURE
- Temporal Dynamics of Antidepressant Ketamine Effects on Glutamine Cycling Follow Regional Fingerprints of AMPA and NMDA Receptor Densities
- (2016) Meng Li et al. NEUROPSYCHOPHARMACOLOGY
- Extensive phosphorylation of AMPA receptors in neurons
- (2016) Graham H. Diering et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression
- (2016) Bangkun Yang et al. PSYCHOPHARMACOLOGY
- Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine
- (2016) K. Zhang et al. Science Signaling
- Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine
- (2016) K. Zhang et al. Science Signaling
- How does ketamine elicit a rapid antidepressant response?
- (2015) Ege T Kavalali et al. CURRENT OPINION IN PHARMACOLOGY
- Glutamatergic and dopaminergic neurons in the mouse ventral tegmental area
- (2015) Tsuyoshi Yamaguchi et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Activation of a ventral hippocampus–medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine
- (2015) F R Carreno et al. MOLECULAR PSYCHIATRY
- Dopamine depletion of the striatum causes a cell-type specific reorganization of GluN2B- and GluN2D-containing NMDA receptors
- (2015) Xiaoqun Zhang et al. NEUROPHARMACOLOGY
- The role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in depression: Central mediators of pathophysiology and antidepressant activity?
- (2015) Florian Freudenberg et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- An excitatory synapse hypothesis of depression
- (2015) Scott M. Thompson et al. TRENDS IN NEUROSCIENCES
- Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression
- (2015) Rosemary C. Bagot et al. Nature Communications
- R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects
- (2015) C Yang et al. Translational Psychiatry
- Antidepressant mechanism of ketamine: perspective from preclinical studies
- (2015) Lisa Scheuing et al. Frontiers in Neuroscience
- (R,S)-Ketamine Metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine Increase the Mammalian Target of Rapamycin Function
- (2014) Rajib K. Paul et al. ANESTHESIOLOGY
- Restoring Mood Balance in Depression: Ketamine Reverses Deficit in Dopamine-Dependent Synaptic Plasticity
- (2014) Pauline Belujon et al. BIOLOGICAL PSYCHIATRY
- Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices
- (2014) Patrícia O. Ribeiro et al. BRAIN RESEARCH
- Allosteric modulation of GluN2C/GluN2D-containing NMDA receptors bidirectionally modulates dopamine release: implication for Parkinson's disease
- (2014) X Zhang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Impact of adolescent GluA1 AMPA receptor ablation in forebrain excitatory neurons on behavioural correlates of mood disorders
- (2014) Miriam A. Vogt et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Stress and VTA synapses: implications for addiction and depression
- (2014) Abigail M. Polter et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function
- (2014) Yukitoshi Izumi et al. NEUROPHARMACOLOGY
- Enhancing Depression Mechanisms in Midbrain Dopamine Neurons Achieves Homeostatic Resilience
- (2014) A. K. Friedman et al. SCIENCE
- Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: Relevance for mental disorders
- (2013) Dragos Inta et al. HIPPOCAMPUS
- The Neurobehavioral Pharmacology of Ketamine: Implications for Drug Abuse, Addiction, and Psychiatric Disorders
- (2013) K. A. Trujillo et al. ILAR JOURNAL
- Acute Suppression of Spontaneous Neurotransmission Drives Synaptic Potentiation
- (2013) E. Nosyreva et al. JOURNAL OF NEUROSCIENCE
- A recollection of mTOR signaling in learning and memory
- (2013) T. E. Graber et al. LEARNING & MEMORY
- Ketamine: synaptogenesis, immunomodulation and glycogen synthase kinase-3 as underlying mechanisms of its antidepressant properties
- (2013) P A Zunszain et al. MOLECULAR PSYCHIATRY
- NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
- (2013) Pierre Paoletti et al. NATURE REVIEWS NEUROSCIENCE
- The brain reward circuitry in mood disorders
- (2013) Scott J. Russo et al. NATURE REVIEWS NEUROSCIENCE
- AMPARs and Synaptic Plasticity: The Last 25 Years
- (2013) Richard L. Huganir et al. NEURON
- Long-lasting changes in hippocampal synaptic plasticity and cognition in an animal model of NMDA receptor dysfunction in psychosis
- (2013) Valentina Wiescholleck et al. NEUROPHARMACOLOGY
- R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine
- (2013) Ji-chun Zhang et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Knockdown of BNST GluN2B-containing NMDA receptors mimics the actions of ketamine on novelty-induced hypophagia
- (2013) K M Louderback et al. Translational Psychiatry
- Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants
- (2013) Caroline A. Browne et al. Frontiers in Pharmacology
- Significant increase in anxiety during aging in mGlu5 receptor knockout mice
- (2012) D. Inta et al. BEHAVIOURAL BRAIN RESEARCH
- The Stability of NR2B in the Nucleus Accumbens Controls Behavioral and Synaptic Adaptations to Chronic Stress
- (2012) Bo Jiang et al. BIOLOGICAL PSYCHIATRY
- The Action of Antidepressants on the Glutamate System: Regulation of Glutamate Release and Glutamate Receptors
- (2012) Laura Musazzi et al. BIOLOGICAL PSYCHIATRY
- Ventral Tegmental Area Glutamate Neurons: Electrophysiological Properties and Projections
- (2012) T. S. Hnasko et al. JOURNAL OF NEUROSCIENCE
- Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons
- (2012) Dipesh Chaudhury et al. NATURE
- mGlu2/3 and mGlu5 receptors: Potential targets for novel antidepressants
- (2012) Shigeyuki Chaki et al. NEUROPHARMACOLOGY
- Synaptic plasticity in depression: Molecular, cellular and functional correlates
- (2012) W.N. Marsden PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
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- (2012) Agata Chandran et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
- (2011) Anita E. Autry et al. NATURE
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- (2011) Stephan Lammel et al. NEURON
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- (2011) Karima Chergui NEUROPHARMACOLOGY
- Signaling pathways underlying the rapid antidepressant actions of ketamine
- (2011) Ronald S. Duman et al. NEUROPHARMACOLOGY
- Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage
- (2011) Loredana Stoica et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function
- (2011) G. Turrigiano Cold Spring Harbor Perspectives in Biology
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
- (2010) N. Li et al. SCIENCE
- Long-term potentiation in the nucleus accumbens requires both NR2A- and NR2B-containing N-methyl-d-aspartate receptors
- (2008) Sietske M. Schotanus et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex
- (2008) L. Sui et al. LEARNING & MEMORY
- Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System
- (2008) Stephan Lammel et al. NEURON
- Dopamine D1 receptors and group I metabotropic glutamate receptors contribute to the induction of long-term potentiation in the nucleus accumbens
- (2008) Sietske M. Schotanus et al. NEUROPHARMACOLOGY
- Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors
- (2007) Sungho Maeng et al. BIOLOGICAL PSYCHIATRY
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