Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator

Neuroanatomic Differences Associated With Stress Susceptibility and Resilience

(2016) Christoph Anacker et al.   BIOLOGICAL PSYCHIATRY

A Pharmacogenetic ‘Restriction-of-Function’ Approach Reveals Evidence for Anxiolytic-Like Actions Mediated by α5-Containing GABAA Receptors in Mice

(2016) Lauren M Behlke et al.   NEUROPSYCHOPHARMACOLOGY

The evolution of the molecular response to stress and its relevance to trauma and stressor-related disorders

(2016) Ian P. Burges Watson et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Somatostatin, neuronal vulnerability and behavioral emotionality

(2015) L C Lin et al.   MOLECULAR PSYCHIATRY

Erratum: Corrigendum: Regulating anxiety with extrasynaptic inhibition

(2015) Paolo Botta et al.   NATURE NEUROSCIENCE

Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors

(2015) Jonathan Fischell et al.   NEUROPSYCHOPHARMACOLOGY

Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice

(2015) Gaël Quesseveur et al.   Frontiers in Cellular Neuroscience

Exploring Female Mice Interstrain Differences Relevant for Models of Depression

(2015) Daniela de Sá-Calçada et al.   Frontiers in Behavioral Neuroscience

Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: The approximated activation of receptor subtypes may explain behavioral effects

(2014) Aleksandar Lj. Obradović et al.   BRAIN RESEARCH

Sustained increase in α5GABAA receptor function impairs memory after anesthesia

(2014) Agnieszka A. Zurek et al.   JOURNAL OF CLINICAL INVESTIGATION

NMDA Receptors Are Upregulated and Trafficked to the Plasma Membrane after Sigma-1 Receptor Activation in the Rat Hippocampus

(2014) M. Pabba et al.   JOURNAL OF NEUROSCIENCE

Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings

(2014) G Northoff et al.   MOLECULAR PSYCHIATRY

Opposing Effects of Acute versus Chronic Blockade of Frontal Cortex Somatostatin-Positive Inhibitory Neurons on Behavioral Emotionality in Mice

(2014) Amelie Soumier et al.   NEUROPSYCHOPHARMACOLOGY

Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010

(2013) Alize J. Ferrari et al.   PLOS MEDICINE

The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species

(2013) Marianne L. Seney et al.   Frontiers in Psychiatry

Brain-Derived Neurotrophic Factor Signaling and Subgenual Anterior Cingulate Cortex Dysfunction in Major Depressive Disorder

(2012) Adam Tripp et al.   AMERICAN JOURNAL OF PSYCHIATRY

Relationship of Ketamine's Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression

(2012) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial

(2012) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

Chronic stress alters inhibitory networks in the medial prefrontal cortex of adult mice

(2012) Javier Gilabert-Juan et al.   Brain Structure & Function

Axo-Dendritic Overlap and Laminar Projection Can Explain Interneuron Connectivity to Pyramidal Cells

(2012) Adam M. Packer et al.   CEREBRAL CORTEX

Extrasynaptic GABAA Receptors: Their Function in the CNS and Implications for Disease

(2012) Stephen G. Brickley et al.   NEURON

Selective GABAA α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment

(2012) Ming Teng Koh et al.   NEUROPHARMACOLOGY

Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: Relevance to emotionality and sex

(2011) Jean-Philippe Guilloux et al.   JOURNAL OF NEUROSCIENCE METHODS

Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression

(2011) J-P Guilloux et al.   MOLECULAR PSYCHIATRY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Reduced somatostatin in subgenual anterior cingulate cortex in major depression

(2011) Adam Tripp et al.   NEUROBIOLOGY OF DISEASE

Altered aortic vascular reactivity in the unpredictable chronic mild stress model of depression in mice

(2011) Elsa Isingrini et al.   PHYSIOLOGY & BEHAVIOR

Social Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress

(2011) Xian-cang Ma et al.   PLoS One

Fluoxetine Effect on Aortic Nitric Oxide-Dependent Vasorelaxation in the Unpredictable Chronic Mild Stress Model of Depression in Mice

(2011) E. Isingrini et al.   PSYCHOSOMATIC MEDICINE

Resilient emotionality and molecular compensation in mice lacking the oligodendrocyte-specific gene Cnp1

(2011) N M Edgar et al.   Translational Psychiatry

Combining Antidepressant Medications: A Good Idea?

(2010) A. John Rush   AMERICAN JOURNAL OF PSYCHIATRY

γ-Aminobutyric Acid-Type A Receptor Deficits Cause Hypothalamic-Pituitary-Adrenal Axis Hyperactivity and Antidepressant Drug Sensitivity Reminiscent of Melancholic Forms of Depression

(2010) Qiuying Shen et al.   BIOLOGICAL PSYCHIATRY

The GABAergic deficit hypothesis of major depressive disorder

(2010) B Luscher et al.   MOLECULAR PSYCHIATRY

Regulation of GABAA Receptor Subunit Expression by Pharmacological Agents

(2010) M. Uusi-Oukari et al.   PHARMACOLOGICAL REVIEWS

Novel positive allosteric modulators of GABAA receptors: Do subtle differences in activity at α1 plus α5 versus α2 plus α3 subunits account for dissimilarities in behavioral effects in rats?

(2010) Miroslav M. Savić et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis

(2009) Andrea Cipriani et al.   LANCET

Prominent hippocampal CA3 gene expression profile in neurocognitive aging

(2009) Rebecca P. Haberman et al.   NEUROBIOLOGY OF AGING

Corticolimbic Transcriptome Changes are State-Dependent and Region-Specific in a Rodent Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   NEUROPSYCHOPHARMACOLOGY