The Role of GluN2A and GluN2B Subunits on the Effects of NMDA Receptor Antagonists in Modeling Schizophrenia and Treating Refractory Depression

GluN2A and GluN2B NMDA Receptor Subunits Differentially Modulate Striatal Output Pathways and Contribute to Levodopa-Induced Abnormal Involuntary Movements in Dyskinetic Rats

(2013) Omar S. Mabrouk et al.   ACS Chemical Neuroscience

Late Adolescent Expression of GluN2B Transmission in the Prefrontal Cortex Is Input-Specific and Requires Postsynaptic Protein Kinase A and D1 Dopamine Receptor Signaling

(2013) Eden Flores-Barrera et al.   BIOLOGICAL PSYCHIATRY

NR2A- and NR2B-containing NMDA receptors in the prelimbic medial prefrontal cortex differentially mediate trace, delay, and contextual fear conditioning

(2013) M. R. Gilmartin et al.   LEARNING & MEMORY

NMDA Receptors Subserve Persistent Neuronal Firing during Working Memory in Dorsolateral Prefrontal Cortex

(2013) Min Wang et al.   NEURON

GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects

(2013) Jeffrey Burgdorf et al.   NEUROPSYCHOPHARMACOLOGY

GluN2B Antagonism Affects Interneurons and Leads to Immediate and Persistent Changes in Synaptic Plasticity, Oscillations and Behavior

(2013) Jesse E Hanson et al.   NEUROPSYCHOPHARMACOLOGY

A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression

(2013) Chen Zhang et al.   PSYCHOPHARMACOLOGY

Antidepressant effects of AMPA and ketamine combination: role of hippocampal BDNF, synapsin, and mTOR

(2013) Luli Akinfiresoye et al.   PSYCHOPHARMACOLOGY

A Randomized Trial of a Low-Trapping Nonselective N-Methyl-D-Aspartate Channel Blocker in Major Depression

(2012) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

(2012) Vanja Duric et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A Randomized, Placebo-Controlled, Crossover Pilot Trial of the Oral Selective NR2B Antagonist MK-0657 in Patients With Treatment-Resistant Major Depressive Disorder

(2012) Lobna Ibrahim et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

TMPRSS9 and GRIN2B Are Associated with Neuroticism: a Genome-Wide Association Study in a European Sample

(2012) Nagesh Aragam et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression

(2011) Hiroyuki Koike et al.   BEHAVIOURAL BRAIN RESEARCH

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

Differential Role of NR2A and NR2B Subunits in N-Methyl-D-Aspartate Receptor Antagonist-Induced Aberrant Cortical Gamma Oscillations

(2011) Bernat Kocsis   BIOLOGICAL PSYCHIATRY

Importance of inter-hemispheric prefrontal connection in the effects of non-competitive NMDA receptor antagonists

(2011) Xavier López-Gil et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Is the Acute NMDA Receptor Hypofunction a Valid Model of Schizophrenia?

(2011) A. Adell et al.   SCHIZOPHRENIA BULLETIN

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Reduced spatial learning in mice treated with NVP-AAM077 through down-regulating neurogenesis

(2009) Mei Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanism of differential control of NMDA receptor activity by NR2 subunits

(2009) Marc Gielen et al.   NATURE

Glutamate-based antidepressants: 20 years on

(2009) Phil Skolnick et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

(2008) Sheldon H. Preskorn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression

(2008) Anteneh M. Feyissa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

(2008) John E. Lisman et al.   TRENDS IN NEUROSCIENCES

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

(2007) Sungho Maeng et al.   BIOLOGICAL PSYCHIATRY