Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

Quantitative chiral and achiral determination of ketamine and its metabolites by LC–MS/MS in human serum, urine and fecal samples

(2017) Mahmoud Hasan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus

(2017) Li Zhou et al.   Cell Reports

Reward and Aversion

(2016) Hailan Hu   Annual Review of Neuroscience

A thalamic input to the nucleus accumbens mediates opiate dependence

(2016) Yingjie Zhu et al.   NATURE

A basal ganglia circuit for evaluating action outcomes

(2016) Marcus Stephenson-Jones et al.   NATURE

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice

(2016) Salvatore Lecca et al.   NATURE MEDICINE

mGluR-LTD at Excitatory and Inhibitory Synapses in the Lateral Habenula Tunes Neuronal Output

(2016) Kristina Valentinova et al.   Cell Reports

Habenula Lesions Reveal that Multiple Mechanisms Underlie Dopamine Prediction Errors

(2015) Ju Tian et al.   NEURON

Arc Regulates Experience-Dependent Persistent Firing Patterns in Frontal Cortex

(2014) M. Ren et al.   JOURNAL OF NEUROSCIENCE

Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses

(2014) E. S. Gideons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment

(2014) S. J. Shabel et al.   SCIENCE

T-Type Ca2+ Channels in Normal and Abnormal Brain Functions

(2013) Eunji Cheong et al.   PHYSIOLOGICAL REVIEWS

Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism

(2013) Valentina Gigliucci et al.   PSYCHOPHARMACOLOGY

 CaMKII in Lateral Habenula Mediates Core Symptoms of Depression

(2013) K. Li et al.   SCIENCE

Fluoxetine impairs GABAergic signaling in hippocampal slices from neonatal rats

(2013) Maddalena D. Caiati et al.   Frontiers in Cellular Neuroscience

Molecular characterization of the subnuclei in rat habenula

(2012) Hidenori Aizawa et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

(2012) Kay M. Tye et al.   NATURE

Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance

(2012) Alice M Stamatakis et al.   NATURE NEUROSCIENCE

Input to the Lateral Habenula from the Basal Ganglia Is Excitatory, Aversive, and Suppressed by Serotonin

(2012) Steven J. Shabel et al.   NEURON

Synaptic potentiation onto habenula neurons in the learned helplessness model of depression

(2011) Bo Li et al.   NATURE

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Differential Regulation of the Excitability of Prefrontal Cortical Fast-Spiking Interneurons and Pyramidal Neurons by Serotonin and Fluoxetine

(2011) Ping Zhong et al.   PLoS One

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Human memory strength is predicted by theta-frequency phase-locking of single neurons

(2010) Ueli Rutishauser et al.   NATURE

Morphological and electrophysiological characteristics of neurons within identified subnuclei of the lateral habenula in rat brain slices

(2010) T. Weiss et al.   NEUROSCIENCE

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

The Rostromedial Tegmental Nucleus (RMTg), a GABAergic Afferent to Midbrain Dopamine Neurons, Encodes Aversive Stimuli and Inhibits Motor Responses

(2009) Thomas C. Jhou et al.   NEURON

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

(2007) Sungho Maeng et al.   BIOLOGICAL PSYCHIATRY