Catalytic asymmetric synthesis of spirooxindoles: recent developments
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Title
Catalytic asymmetric synthesis of spirooxindoles: recent developments
Authors
Keywords
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Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 50, Pages 6607-6621
Publisher
Royal Society of Chemistry (RSC)
Online
2018-05-04
DOI
10.1039/c8cc02364f
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Note: Only part of the references are listed.- Enantioselective Synthesis of the Spirotropanyl Oxindole Scaffold through Bimetallic Relay Catalysis
- (2018) Zhi-Jun Jia et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Enantioselective Tandem Michael Addition of Tryptamine-Derived Oxindoles to Alkynones: Concise Synthesis of Strychnos Alkaloids
- (2018) Weigang He et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Diastereo- and Enantioselective Synthesis of Spirooxindoles with Contiguous Tetrasubstituted Stereocenters via Catalytic Coupling of Two Tertiary Radicals
- (2018) Zhi-Yong Song et al. JOURNAL OF ORGANIC CHEMISTRY
- Organocatalytic [3 + 2] cycloaddition of oxindole-based azomethine ylides with 3-nitrochromenes: a facile approach to enantioenriched polycyclic spirooxindole-chromane adducts
- (2018) Shiqi Wu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Catalytic asymmetric construction of spiropyrrolidines via 1,3-dipolar cycloaddition of azomethine ylides
- (2018) Xin Fang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Remote Asymmetric Oxa-Diels–Alder Reaction of 5-Allylic Furfurals via Dearomatizative Tetraenamine Catalysis
- (2018) Xiao-Long He et al. ORGANIC LETTERS
- Diastereo- and Enantioselective Dearomative [3 + 2] Cycloaddition Reaction of 2-Nitrobenzofurans with 3-Isothiocyanato Oxindoles
- (2018) Jian-Qiang Zhao et al. ORGANIC LETTERS
- Diastereodivergent asymmetric Michael-alkylation reactions using chiral N,N′-dioxide/metal complexes
- (2018) Yulong Kuang et al. Chemical Science
- Catalytic Kinetic Resolution of Spiro-Epoxyoxindoles with 1-Naphthols: Switchable Asymmetric Tandem Dearomatization/Oxa-Michael Reaction and Friedel–Crafts Alkylation of 1-Naphthols at the C4 Position
- (2018) Gongming Zhu et al. ACS Catalysis
- Organocatalytic Michael/cyclization cascade reactions of 3-isothiocyanato oxindoles with 3-trifluoroethylidene oxindoles: an approach for the synthesis of 3′-trifluoromethyl substituted 3,2′-pyrrolidinyl-bispirooxindoles
- (2018) Wen-Run Zhu et al. Organic Chemistry Frontiers
- Zinc-Catalyzed Enantioselective Dearomative [3+2] Cycloaddition Reaction of 3-Nitrobenzothiophenes and 3-Nitrothieno[2,3-b ]yridine with 3-Isothiocyanato Oxindoles
- (2018) Deng-Feng Yue et al. ADVANCED SYNTHESIS & CATALYSIS
- Facile Synthesis of Spirooxindoles via an Enantioselective Organocatalyzed Sequential Reaction of Oxindoles with Ynone
- (2017) Hiroaki Sasai et al. HETEROCYCLES
- Assembly of Indolenines, 3-Amino Oxindoles, and Aldehydes into Indolenine-Substituted Spiro[pyrrolidin-2,3′-oxindoles] via 1,3-Dipolar Cycloaddition with Divergent Diastereoselectivities
- (2017) Guodong Zhu et al. JOURNAL OF ORGANIC CHEMISTRY
- Asymmetric Darzens Reaction of Isatins with Diazoacetamides Catalyzed by Chiral BINOL–Titanium Complex
- (2017) Guo-Li Chai et al. JOURNAL OF ORGANIC CHEMISTRY
- L-Pyroglutamic Sulphonamide as Hydrogen-Bonding Organocatalyst: Enantioselective Diels–Alder Cyclization to Construct Carbazolespirooxindoles
- (2017) Ji-Wei Ren et al. JOURNAL OF ORGANIC CHEMISTRY
- Organocatalytic Enantioselective Michael/Cyclization Domino Reaction between 3-Amideoxindoles and α,β-Unsaturated Aldehydes: One-Pot Preparation of Chiral Spirocyclic Oxindole-γ-lactams
- (2017) Peng Yang et al. JOURNAL OF ORGANIC CHEMISTRY
- Indolylmethanols as Reactants in Catalytic Asymmetric Reactions
- (2017) Guang-Jian Mei et al. JOURNAL OF ORGANIC CHEMISTRY
- Spirooxindoles as Potential Pharmacophores
- (2017) Siva S. Panda et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Organocatalytic Access to Enantioenriched Spirooxindole-Based 4-Methyleneazetidines
- (2017) Giulia Rainoldi et al. MOLECULES
- Chiral squaramide-catalysed enantioselective Michael/cyclization cascade reaction of 3-hydroxyoxindoles with α,β-unsaturated N-acylated succinimides
- (2017) Sheng Ming et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Enantioselective synthesis of spiro γ-butyrolactones by N-heterocyclic carbene (NHC)-catalyzed formal [3 + 2] annulation of enals with 3-hydroxy oxindoles
- (2017) Subrata Mukherjee et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- An enantioselective synthesis of spiro-oxindole-based 3,4-dihydropyrroles via a Michael/cyclization cascade of 3-aminooxindoles with 2-enoylpyridines
- (2017) Baodong Cui et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Diastereo- and enantioselective construction of spirooxindole scaffolds through a catalytic asymmetric [3 + 3] cycloaddition
- (2017) Can Li et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Organocatalytic Enantioselective Michael–Michael–Michael–Aldol Condensation Reactions: Control of Six Stereocenters in a Quadruple-Cascade Asymmetric Synthesis of Polysubstituted Spirocyclic Oxindoles
- (2017) Prakash D. Chaudhari et al. ORGANIC LETTERS
- Enantioselective 1,3-Dipolar Cycloaddition of Methyleneindolinones with α-Diazomethylphosphonate to Access Chiral Spiro-phosphonylpyrazoline-oxindoles Catalyzed by Tertiary Amine Thiourea and 1,5-Diazabicyclo[4.3.0]non-5-ene
- (2017) Nan Huang et al. ORGANIC LETTERS
- Reversal of Selectivity in C3-Allylation and Formal [3 + 2]-Cycloaddition of Spiro-epoxyoxindole: Unified Synthesis of Spiro-furanooxindole, (±)-N-Methylcoerulescine, (±)-Physovenine, and 3a-Allylhexahydropyrrolo[2,3-b]indole
- (2017) Saumen Hajra et al. ORGANIC LETTERS
- Asymmetric [3 + 2] Cycloaddition of 3-Amino Oxindole-Based Azomethine Ylides and α,β-Enones with Divergent Diastereocontrol on the Spiro[pyrrolidine-oxindoles]
- (2017) Guodong Zhu et al. ORGANIC LETTERS
- N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate
- (2017) Xiang-Yu Chen et al. Chemical Science
- Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions
- (2017) Wei-Jie Huang et al. Organic Chemistry Frontiers
- Squaramide-catalyzed asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles with chalcones for synthesis of pyrrolidinyl spirooxindoles
- (2017) Ye Lin et al. Organic Chemistry Frontiers
- Formal [3 + 2] cycloaddition of α-unsubstituted isocyanoacetates and methyleneindolinones: enantioselective synthesis of spirooxindoles
- (2017) Xiao-Jiao Peng et al. Organic Chemistry Frontiers
- Asymmetric Synthesis of 2′-Trifluoromethylated Spiro-pyrrolidine-3,3′-oxindolesviaSquaramide-Catalyzed Umpolung and 1,3-Dipolar Cycloaddition
- (2016) Jinhuan Su et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2016) Jia-Le Wu et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2016) Hong-Wu Zhao et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2016) Muthukumar G. Sankar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Phosphine-mediated Highly Enantioselective Spirocyclization with Ketimines as Substrates
- (2016) Xiaoyu Han et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Organocatalytic Domino Oxa-Michael/1,6-Addition Reactions: Asymmetric Synthesis of Chromans Bearing Oxindole Scaffolds
- (2016) Kun Zhao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Catalyst-Controlled Switch in Chemo- and Diastereoselectivities: Annulations of Morita-Baylis-Hillman Carbonates from Isatins
- (2016) Gu Zhan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents
- (2016) Bin Yu et al. Anti-Cancer Agents in Medicinal Chemistry
- Highly diastereoselective entry into chiral spirooxindole-based 4-methyleneazetidines via formal [2+2] annulation reaction
- (2016) G. Rainoldi et al. CHEMICAL COMMUNICATIONS
- Asymmetric synthesis of 3,3′-pyrrolidinyl-dispirooxindoles via a one-pot organocatalytic Mannich/deprotection/aza-Michael sequence
- (2016) Kun Zhao et al. CHEMICAL COMMUNICATIONS
- An asymmetric assembly of spirooxindole dihydropyranones through a direct enantioselective organocatalytic vinylogous aldol-cyclization cascade reaction of 3-alkylidene oxindoles with isatins
- (2016) Jeng-Liang Han et al. CHEMICAL COMMUNICATIONS
- Organocatalytic cascade Michael/Michael reaction for the asymmetric synthesis of spirooxindoles containing five contiguous stereocenters
- (2016) Bo-Liang Zhao et al. CHEMICAL COMMUNICATIONS
- The enantioselective construction of chiral spirooxindole-based 4-thiazolidinone via asymmetric catalytic formal [3+2] annulation using a bifunctional catalyst
- (2016) Ping Cheng et al. CHEMICAL COMMUNICATIONS
- Substrate-controlled switchable asymmetric annulations to access polyheterocyclic skeletons
- (2016) Kai-Kai Wang et al. CHEMICAL COMMUNICATIONS
- Organocatalytic asymmetric [3+2] cycloaddition of N-2,2,2-trifluoroethylisatin ketimines with 3-alkenyl-5-arylfuran-2(3H)-ones
- (2016) Zhen-Hua Wang et al. CHEMICAL COMMUNICATIONS
- Catalytic asymmetric chemoselective 1,3-dipolar cycloadditions of an azomethine ylide with isatin-derived imines: diastereo- and enantioselective construction of a spiro[imidazolidine-2,3′-oxindole] framework
- (2016) Yue-Ming Wang et al. CHEMICAL COMMUNICATIONS
- The First Enantioselective Organocatalytic Synthesis of 3-Spiro-α-Alkylidene-γ-Butyrolactone Oxindoles
- (2016) Lucia Cerisoli et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Diels-Alder Cycloadditions of Trifluoromethylated Dienophiles Under Trienamine Catalysis
- (2016) Xin Yuan et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Stereoselective [3+2] Cycloadditions of Chiral Palladium-ContainingN1-1,3-Dipoles: A Divergent Approach to Enantioenriched Spirooxindoles
- (2016) Tian-Ren Li et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantioselective Cascade Reaction of α-Cyano Ketones and Isatylidene Malononitriles: Asymmetric Construction of Spiro[4H-pyran-oxindoles]
- (2016) Jin Xie et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- A Brønsted Acid-Primary Amine as a Synergistic Catalyst for Stereoselective Asymmetric Diels-Alder Reactions
- (2016) Dhevalapally B. Ramachary et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Nitroso Aldol Intramolecular Transesterification Cyclization Domino Reaction for Highly Effective Construction of Chiral Spirooxindoles
- (2016) Shan-Ping Ji et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Organocatalytic Asymmetric Michael/Cyclization Cascade Reaction of 3-Isothiocyanato Oxindoles with Maleimides for the Efficient Construction of Pyrrolidonyl Spirooxindoles
- (2016) Lei Liu et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Water-Promoted Regiospecific Azidolysis and Copper-Catalyzed Azide–Alkyne Cycloaddition: One-Pot Synthesis of 3-Hydroxy-1-alkyl-3-[(4-aryl/alkyl-1H-1,2,3-triazol-1-yl)methyl]indolin-2-ones
- (2016) Kapil Kumar et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Construction of Spirocyclic Oxindoles via Tandem Michael/Michael Reactions Catalyzed by Multifunctional Quaternary Phosphonium Salt
- (2016) Jiaxing Zhang et al. JOURNAL OF ORGANIC CHEMISTRY
- Organocatalytic Asymmetric Biginelli-like Reaction Involving Isatin
- (2016) Mattia Stucchi et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Construction of Tetrahydroquinolin-5-one-Based Spirooxindole Scaffold via an Organocatalytic Asymmetric Multicomponent [3 + 3] Cyclization
- (2016) Qiu-Ning Zhu et al. JOURNAL OF ORGANIC CHEMISTRY
- 1-Hydroxybenzotriazole-Assisted, N-Heterocyclic Carbene Catalyzed β-Functionalization of Saturated Carboxylic Esters: Access to Spirooxindole Lactones
- (2016) Jianfeng Xu et al. JOURNAL OF ORGANIC CHEMISTRY
- Organocatalytic One-Pot Asymmetric Synthesis of Thiolated Spiro-γ-lactam Oxindoles Bearing Three Stereocenters
- (2016) Xin Huang et al. JOURNAL OF ORGANIC CHEMISTRY
- Catalytic formal cycloadditions between anhydrides and ketones: excellent enantio and diastereocontrol, controllable decarboxylation and the formation of adjacent quaternary stereocentres
- (2016) Claudio Cornaggia et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- The organocatalytic asymmetric Neber reaction for the enantioselective synthesis of spirooxindole 2H-azirines
- (2016) Jian-Qiang Zhao et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Catalytic enantioselective cascade Michael/cyclization reaction of 3-isothiocyanato oxindoles with exocyclic α,β-unsaturated ketones en route to 3,2′-pyrrolidinyl bispirooxindoles
- (2016) Satavisha Kayal et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Organocatalyzed enantioselective Michael addition/cyclization cascade reaction of 3-isothiocyanato oxindoles with arylidene malonates
- (2016) Raghunath Chowdhury et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- N-Heterocyclic carbene-catalyzed [4 + 2] cyclization of α,β-unsaturated carboxylic acids bearing γ-H with isatins: an enantioselective synthesis of spirocyclic oxindole–dihydropyranones
- (2016) Ling Zhu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Highly enantioselective synthesis of spirocyclopropyloxindoles via a Rh(ii)-catalyzed asymmetric cyclopropanation reaction
- (2016) Yongjian Chi et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Stereoselective synthesis of spirooxindole derivatives using an organocatalyzed tandem Michael–Michael reaction
- (2016) Huicai Huang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Enantioselective synthesis of spiro[indoline-3,4′-pyrano[2,3-c]pyrazole] derivatives via an organocatalytic asymmetric Michael/cyclization cascade reaction
- (2016) Jin Xie et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Catalytic asymmetric hetero-Diels–Alder reactions of enones with isatins to access functionalized spirooxindole tetrahydropyrans: scope, derivatization, and discovery of bioactives
- (2016) Hai-Lei Cui et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Synthesis of Chiral Spiro-Aziridine Oxindoles via Aza-Corey–Chaykovsky Reaction of Isatin Derived N-tert-Butanesulfinyl Ketimines
- (2016) Saumen Hajra et al. ORGANIC LETTERS
- N-Heterocyclic Carbene Catalyzed [4 + 2] Annulation Reactions with in Situ Generated Heterocyclic ortho-Quinodimethanes
- (2016) Jianfeng Xu et al. ORGANIC LETTERS
- Meeting Organocatalysis with Drug Discovery: Asymmetric Synthesis of 3,3′-Spirooxindoles Fused with Tetrahydrothiopyrans as Novel p53-MDM2 Inhibitors
- (2016) Shengzheng Wang et al. ORGANIC LETTERS
- α-Regioselective Asymmetric [3 + 2] Annulations of Morita–Baylis–Hillman Carbonates with Cyclic 1-Azadienes and Mechanism Elucidation
- (2016) Kai-Kai Wang et al. ORGANIC LETTERS
- Enantioselective Synthesis of Dihydrospiro[indoline-3,4′-pyrano[2,3-c]pyrazole] Derivatives via Michael/Hemiketalization Reaction
- (2016) Nandarapu Kumarswamyreddy et al. ORGANIC LETTERS
- Thiourea–Quaternary Ammonium Salt Catalyzed Asymmetric 1, 3-Dipolar Cycloaddition of Imino Esters To Construct Spiro[pyrrolidin-3,3′-oxindoles]
- (2016) Jia-Xing Zhang et al. ORGANIC LETTERS
- PyBidine–Ni(OAc)2-Catalyzed Michael/Aldol Reaction of Methyleneindolinones and Thiosalicylaldehydes for Stereochemically Divergent Thiochromanyl-spirooxindoles
- (2016) Takayoshi Arai et al. ORGANIC LETTERS
- Organocatalytic asymmetric synthesis of trans -configured trispirooxindoles through a cascade Michael-cyclization reaction
- (2016) Chaoling Wu et al. TETRAHEDRON LETTERS
- Nickel(ii)-catalyzed enantioselective cyclopropanation of 3-alkenyl-oxindoles with phenyliodonium ylide via free carbene
- (2016) Jing Guo et al. Chemical Science
- Origin of Stereoselectivity in Cooperative Asymmetric Catalysis Involving N-Heterocyclic Carbenes and Lewis Acids toward the Synthesis of Spirooxindole Lactone
- (2016) Yernaidu Reddi et al. ACS Catalysis
- Enantioselective construction of novel chiral spirooxindoles incorporating a thiazole nucleus
- (2016) L.-Y. Cui et al. RSC Advances
- Construction of highly enantioselective spiro-oxindole derivatives with fused chromene via organocascade catalysis
- (2016) Prathibha Kumari et al. RSC Advances
- Enantioselective Synthesis of Spirooxindole Enols: Regioselective and Asymmetric [3+2] Cyclization of 3-Isothiocyanato Oxindoles with Dibenzylidene Ketones
- (2016) Dan Du et al. ChemistryOpen
- Therapeutic Potential of Spirooxindoles as Antiviral Agents
- (2016) Na Ye et al. ACS Infectious Diseases
- N-Heterocyclic carbene-catalyzed [4 + 2] annulation of α,β-unsaturated carboxylic acids: enantioselective synthesis of dihydropyridinones and spirocyclic oxindolodihydropyridinones
- (2016) Wen-Qiang Jia et al. Organic Chemistry Frontiers
- Recent Advances in Green Synthesis of 3,3′-Spirooxindoles via Isatin-based One-pot Multicomponent Cascade Reactions in Aqueous Medium
- (2016) Li-Jun Yan et al. ChemistrySelect
- Asymmetric Catalytic Cascade Reactions for Constructing Diverse Scaffolds and Complex Molecules
- (2015) Yao Wang et al. ACCOUNTS OF CHEMICAL RESEARCH
- Organocatalytic Enantioselective Synthesis of Polysubstituted Spirooxindoles using a Tandem Michael-Michael Reaction
- (2015) Santhi Abbaraju et al. ADVANCED SYNTHESIS & CATALYSIS
- Recent Advances of α-Isothiocyanato Compounds in the Catalytic Asymmetric Reaction
- (2015) Wen-Yong Han et al. ADVANCED SYNTHESIS & CATALYSIS
- Enantioselective Vinylogous Michael/Cyclization Cascade Reaction of Acyclic β,γ-Unsaturated Amides with Isatylidene Malononitriles: Asymmetric Construction of Spirocyclic Oxindoles
- (2015) Tian-Ze Li et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2015) Hong-Wu Zhao et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2015) Quantao Sun et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2015) Qiang-Sheng Sun et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2015) Ming-Yue Wu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2015) Haifeng Zheng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2015) Dan Du et al. ChemCatChem
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- (2015) Xiaohu Zhao et al. CHEMICAL COMMUNICATIONS
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- (2015) Guodong Zhu et al. CHEMICAL COMMUNICATIONS
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- (2015) Mingxia Ma et al. CHEMICAL COMMUNICATIONS
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- (2015) Magda Monari et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2015) Yuanwei Xie et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2015) Dong-Yang Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2015) Yangyan Li et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2015) Bin Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2015) Bin Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2015) Jin-Tang Cheng et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Hong-Wu Zhao et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Yang Wang et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Chengkai Yin et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Yonglei Que et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Delu Jiang et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Jianfeng Zheng et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Lin Chen et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2015) Yong You et al. JOURNAL OF ORGANIC CHEMISTRY
- Diastereo- and Enantioselective Construction of 3,3′-Pyrrolidinyldispirooxindole Framework via Catalytic Asymmetric 1,3-Dipolar Cycloadditions
- (2015) Wei Dai et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective [4 + 1] Annulation Reactions of α-Substituted Ammonium Ylides To Construct Spirocyclic Oxindoles
- (2015) Peng-Fei Zheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular diversity of spirooxindoles. Synthesis and biological activity
- (2015) Tetyana L. Pavlovska et al. MOLECULAR DIVERSITY
- N-heterocyclic carbene-catalyzed [4 + 2] cyclization of 2-bromo-2-enal with 3-alkylenyloxindoles: efficient assembly of spirocarbocyclic oxindole
- (2015) Yuanwei Xie et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters
- (2015) Yong-Yuan Gui et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Catalytic Asymmetric [3 + 2] Cyclization Reactions of 3-Isothiocyanato Oxindoles and Alkynyl Ketones Via an in Situ Generated Magnesium Catalyst
- (2015) Linqing Wang et al. ORGANIC LETTERS
- Zn-Catalyzed Diastereo- and Enantioselective Cascade Reaction of 3-Isothiocyanato Oxindoles and 3-Nitroindoles: Stereocontrolled Syntheses of Polycyclic Spirooxindoles
- (2015) Jian-Qiang Zhao et al. ORGANIC LETTERS
- Asymmetric Michael/Cyclization Cascade Reaction of 3-Isothiocyanato Oxindoles and 3-Nitroindoles with Amino-Thiocarbamate Catalysts: Enantioselective Synthesis of Polycyclic Spirooxindoles
- (2015) Jian-Qiang Zhao et al. ORGANIC LETTERS
- Catalytic Aldol–Cyclization Cascade of 3-Isothiocyanato Oxindoles with α-Ketophosphonates for the Enantioselective Synthesis of β-Amino-α-hydroxyphosphonates
- (2015) Satavisha Kayal et al. ORGANIC LETTERS
- Highly Enantioselective [3 + 2]-Annulation of Isatin-Derived Morita–Baylis–Hillman Adducts with Cyclic Sulfonimines
- (2015) Feng Wei et al. ORGANIC LETTERS
- Recent Advances in Chiral Phosphoric Acid Catalyzed Asymmetric Reactions for the Synthesis of Enantiopure Indole Derivatives
- (2015) Hua Wu et al. SYNTHESIS-STUTTGART
- Quinine-catalyzed asymmetric domino Mannich-cyclization reactions of 3-isothiocyanato oxindoles with imines for the synthesis of spirocyclic oxindoles
- (2015) Mei Bai et al. TETRAHEDRON
- Highly Enantioselective Control of Dynamic Cascade Transformations by Dual Catalysis: Asymmetric Synthesis of Polysubstituted Spirocyclic Oxindoles
- (2015) Samson Afewerki et al. ACS Catalysis
- Organocatalytic Enantioselective Cascade Aza-Michael/Michael Addition Sequence for Asymmetric Synthesis of Chiral Spiro[pyrrolidine-3,3′-oxindole]s
- (2015) Bo-Liang Zhao et al. Asian Journal of Organic Chemistry
- Reaction-Based Mechanistic Investigations of Asymmetric Hetero-Diels-Alder Reactions of Enones with Isatins Catalyzed by Amine-Based Three-Component Catalyst Systems
- (2015) Hai-Lei Cui et al. Asian Journal of Organic Chemistry
- Catalytic asymmetric synthesis of polysubstituted spirocyclopropyl oxindoles: organocatalysis versus transition metal catalysis
- (2015) Zhong-Yan Cao et al. Organic Chemistry Frontiers
- Synthesis of Spiro[chroman/tetrahydrothiophene-3,3′-oxindole] ScaffoldsviaHeteroatom-Michael-Michael Reactions: Easily Controlled EnantioselectivityviaBifunctional Catalysts
- (2014) Youming Huang et al. ADVANCED SYNTHESIS & CATALYSIS
- Phosphine-Catalyzed Asymmetric Formal [4+2] Tandem Cyclization of Activated Dienes with Isatylidenemalononitriles: Enantioselective Synthesis of Multistereogenic Spirocyclic Oxindoles
- (2014) Fang-Le Hu et al. ADVANCED SYNTHESIS & CATALYSIS
- PyBidine-Cu(OTf)2-Catalyzed Asymmetric [3+2] Cycloaddition with Imino Esters: Harmony of Cu-Lewis Acid and Imidazolidine-NH Hydrogen Bonding in Concerto Catalysis
- (2014) Takayoshi Arai et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Triple Relay Catalysis: Enantioselective Synthesis of Spirocyclic Indolines through a One-Pot Process Featuring an Asymmetric 6π Electrocyclization
- (2014) Xiao-Ping Yin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Catalytic Asymmetric Tamura Cycloadditions
- (2014) Francesco Manoni et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Asymmetric Organocatalytic Direct C(sp2)H/C(sp3)H Oxidative Cross-Coupling by Chiral Iodine Reagents
- (2014) Hua Wu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A catalytic asymmetric hetero-Diels–Alder reaction of olefinic azlactones and isatins: facile access to chiral spirooxindole dihydropyranones
- (2014) Tai-Ping Gao et al. CHEMICAL COMMUNICATIONS
- An organocatalytic domino Michael-alkylation reaction: highly enantioselective construction of spiro-cyclopentanoneoxindoles and tetronic acid scaffolds
- (2014) Jing Zhou et al. CHEMICAL COMMUNICATIONS
- A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles
- (2014) Hao Cai et al. CHEMICAL COMMUNICATIONS
- Phosphine-catalyzed asymmetric [4+1] annulation of activated α,β-unsaturated ketones with Morita–Baylis–Hillman carbonates: enantioselective synthesis of spirooxindoles containing two adjacent quaternary stereocenters
- (2014) Fang-Le Hu et al. CHEMICAL COMMUNICATIONS
- Direct enantioselective vinylogous aldol–cyclization cascade reaction of allyl pyrazoleamides with isatins: asymmetric construction of spirocyclic oxindole–dihydropyranones
- (2014) Tian-Ze Li et al. CHEMICAL COMMUNICATIONS
- Highly diastereo- and enantioselective construction of a spiro[cyclopenta[b]indole-1,3′-oxindole] scaffold via catalytic asymmetric formal [3+2] cycloadditions
- (2014) Wei Tan et al. CHEMICAL COMMUNICATIONS
- Organocatalytic Asymmetric Epoxidation and Aziridination of Olefins and Their Synthetic Applications
- (2014) Yingguang Zhu et al. CHEMICAL REVIEWS
- Catalytic Asymmetric Construction of 3,3′-Spirooxindoles Fused with Seven-Membered Rings by Enantioselective Tandem Reactions
- (2014) Yang Wang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantioselective Cascade Michael Addition/Cyclization Reactions of 3-Nitro-2H-Chromenes with 3-Isothiocyanato Oxindoles: Efficient Synthesis of Functionalized Polycyclic Spirooxindoles
- (2014) Fen Tan et al. CHEMISTRY-A EUROPEAN JOURNAL
- Novel Organocatalytic Activation of Unmodified Morita-Baylis-Hillman Alcohols for the Synthesis of Bicyclic α-Alkylidene-Ketones
- (2014) Julian Stiller et al. CHEMISTRY-A EUROPEAN JOURNAL
- Catalytic Asymmetric Formal [3+3] Cycloaddition of an Azomethine Ylide with 3-Indolylmethanol: Enantioselective Construction of a Six-Membered Piperidine Framework
- (2014) Feng Shi et al. CHEMISTRY-A EUROPEAN JOURNAL
- Diastereo- and Enantioselective Construction of a Bispirooxindole Scaffold Containing a Tetrahydro-β-carboline Moiety through an Organocatalytic Asymmetric Cascade Reaction
- (2014) Wei Dai et al. CHEMISTRY-A EUROPEAN JOURNAL
- Facile Synthesis of Chiral Spirooxindole-Based Isotetronic Acids and 5-1H-Pyrrol-2-ones through Cascade Reactions with Bifunctional Organocatalysts
- (2014) Wengang Guo et al. CHEMISTRY-A EUROPEAN JOURNAL
- Asymmetric Tandem 1,5-Hydride Shift/Ring Closure for the Synthesis of Chiral Spirooxindole Tetrahydroquinolines
- (2014) Weidi Cao et al. CHEMISTRY-A EUROPEAN JOURNAL
- Organocatalytic Asymmetric Cascade Reactions of 7-Vinylindoles: Diastereo- and Enantioselective Synthesis of C7-Functionalized Indoles
- (2014) Feng Shi et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Enantioselective Construction of Spirocyclopentaneoxindoles Containing Four Consecutive Stereocenters through an Organocatalytic Iminium-Enamine Cascade Reaction
- (2014) Liang-Zhong Ding et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Catalytic Asymmetric Michael Addition/Cyclization Cascade Reaction of 3-Isothiocyanatooxindoles with Nitro Olefins
- (2014) Satavisha Kayal et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Highly Enantioselective Construction of Polycyclic Spirooxindoles by Organocatalytic 1,3-Dipolar Cycloaddition of 2-Cyclohexenone Catalyzed by Proline-Sulfonamide
- (2014) Jun-An Xiao et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective Construction of Spiro[indoline-3,2′-pyrrole] Framework via Catalytic Asymmetric 1,3-Dipolar Cycloadditions Using Allenes as Equivalents of Alkynes
- (2014) Cong-Shuai Wang et al. JOURNAL OF ORGANIC CHEMISTRY
- Enantio- and Diastereoselective Synthesis of Spiro-epoxyoxindoles
- (2014) Amina Boucherif et al. JOURNAL OF ORGANIC CHEMISTRY
- Organocatalytic enantioselective construction of multi-functionalized spiro oxindole dienes
- (2014) Xiao-Fei Huang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Catalytic functionalization of tertiary alcohols to fully substituted carbon centres
- (2014) Long Chen et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Palladium-Catalyzed Asymmetric Cycloadditions of Vinylcyclopropanes and in Situ Formed Unsaturated Imines: Construction of Structurally and Optically Enriched Spiroindolenines
- (2014) Ze-Shui Liu et al. ORGANIC LETTERS
- Chiral Spirooxindole–Butenolide Synthesis through Asymmetric N-Heterocyclic Carbene-Catalyzed Formal (3 + 2) Annulation of 3-Bromoenals and Isatins
- (2014) Chenguang Zheng et al. ORGANIC LETTERS
- Hydrogen-Bond-Directed Formal [5 + 1] Annulations of Oxindoles with Ester-Linked Bisenones: Facile Access to Chiral Spirooxindole δ-Lactones
- (2014) Shuai Zhao et al. ORGANIC LETTERS
- Bifunctional N-Heterocyclic Carbene-Catalyzed Highly Enantioselective Synthesis of Spirocyclic Oxindolo-β-lactams
- (2014) Han-Ming Zhang et al. ORGANIC LETTERS
- An Organocatalytic Michael–Michael Cascade for the Enantioselective Construction of Spirocyclopentane Bioxindoles: Control of Four Contiguous Stereocenters
- (2014) Wangsheng Sun et al. ORGANIC LETTERS
- Asymmetric Synthesis of 3,3′-Spirooxindoles Fused with Cyclobutanes through Organocatalytic Formal [2 + 2] Cycloadditions under H-Bond-Directing Dienamine Activation
- (2014) Liang-Wen Qi et al. ORGANIC LETTERS
- Asymmetric Synthesis of Spiro-epoxyoxindoles by the Catalytic Darzens Reaction of Isatins with Phenacyl Bromides
- (2014) Yulong Kuang et al. ORGANIC LETTERS
- Recent advances in the synthesis of biologically active spirooxindoles
- (2014) Maria M.M. Santos TETRAHEDRON
- Quinine-catalyzed asymmetric domino Michael-cyclization reaction for the synthesis of spirocyclic oxindoles bearing two spiro quaternary centers and three consecutive stereocenters
- (2014) Bao-Dong Cui et al. TETRAHEDRON
- Imine and iminium precursors as versatile intermediates in enantioselective organocatalysis
- (2014) Antti O. Kataja et al. TETRAHEDRON
- Organocatalytic [4+2] addition reactions via tetraenamine intermediate
- (2014) Julian Stiller et al. Chemical Science
- Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies
- (2014) Daojuan Cheng et al. ACS Catalysis
- Trienamine catalysis with linear deconjugated 3,5-dienones
- (2014) Peng-Qiao Chen et al. Organic Chemistry Frontiers
- Chiral N,N′-dioxide ligands: synthesis, coordination chemistry and asymmetric catalysis
- (2014) Xiaohua Liu et al. Organic Chemistry Frontiers
- Catalytic Asymmetric 1,3-Dipolar Cycloadditions of Alkynes with Isatin-Derived Azomethine Ylides: Enantioselective Synthesis of Spiro[indoline-3,2′-pyrrole] Derivatives
- (2013) Feng Shi et al. ADVANCED SYNTHESIS & CATALYSIS
- Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles
- (2013) Liang Hong et al. ADVANCED SYNTHESIS & CATALYSIS
- Magnesium(ii)-catalyzed asymmetric hetero-Diels–Alder reaction of Brassard's dienes with isatins
- (2013) Jianfeng Zheng et al. CHEMICAL COMMUNICATIONS
- Enantioselective Synthesis of Spirooxindoles via Direct Catalytic Asymmetric Aldol-Type Reaction of Isothiocyanato Oxindoles
- (2013) Shigeki Matsunaga et al. HETEROCYCLES
- Recent Progress on Routes to Spirooxindole Systems Derived from Isatin
- (2013) Min Xia et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Highly Stereoselective Olefin Cyclopropanation of Diazooxindoles Catalyzed by a C2-Symmetric Spiroketal Bisphosphine/Au(I) Complex
- (2013) Zhong-Yan Cao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis of β-lactams by transition metal promoted Staudinger reactions: alternative synthetic approaches from transition metal enhanced organocatalysis to in situ, highly reactive intermediate synthesis and catalytic tandem reactions
- (2013) Robert Tuba ORGANIC & BIOMOLECULAR CHEMISTRY
- Asymmetric synthesis of drug-like spiro[chroman-3,3′-indolin]-2′-ones through aminal-catalysis
- (2013) Dhevalapally B. Ramachary et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks
- (2012) Girija S. Singh et al. CHEMICAL REVIEWS
- Strategies for the enantioselective synthesis of spirooxindoles
- (2012) Nicolas R. Ball-Jones et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A Highly Diastereo- and Enantioselective Hg(II)-Catalyzed Cyclopropanation of Diazooxindoles and Alkenes
- (2012) Zhong-Yan Cao et al. ORGANIC LETTERS
- A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2′-quinoline] Scaffold
- (2012) Feng Shi et al. ORGANIC LETTERS
- ChiralN,N′-Dioxides: New Ligands and Organocatalysts for Catalytic Asymmetric Reactions
- (2011) XiaoHua Liu et al. ACCOUNTS OF CHEMICAL RESEARCH
- Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters
- (2011) Wen-Bing Chen et al. ORGANIC LETTERS
- Synthesis of 3-substituted indoles via reactive alkylideneindolenine intermediates
- (2009) Alessandro Palmieri et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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