4.8 Article

A Highly Diastereo- and Enantioselective Hg(II)-Catalyzed Cyclopropanation of Diazooxindoles and Alkenes

Journal

ORGANIC LETTERS
Volume 15, Issue 1, Pages 42-45

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol302998m

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Funding

  1. NSFC [21172075, 21222204]
  2. 973 program [2011CB808600]
  3. Innovation Program of SMEC [12ZZ046]

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It is reported for the first time that Hg(II) can catalyze the cyclopropanation of diazo reagents and alkenes, which contributes to the unprecedented highly diastereo- and enantioselective synthesis of spirocyclopropyloxindoles.

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