Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles
Authors
Keywords
-
Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 355, Issue 6, Pages 1023-1052
Publisher
Wiley
Online
2013-02-23
DOI
10.1002/adsc.201200808
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Core Scaffold-Inspired Concise Synthesis of Chiral Spirooxindole-Pyranopyrimidines with Broad-Spectrum Anticancer Potency
- (2012) Xianxing Jiang et al. ADVANCED SYNTHESIS & CATALYSIS
- An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones
- (2012) Julien Dugal-Tessier et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives
- (2012) Shu-Wen Duan et al. CHEMICAL COMMUNICATIONS
- Organocatalytic stereocontrolled synthesis of 3,3′-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones
- (2012) Liang-Liang Wang et al. CHEMICAL COMMUNICATIONS
- Catalytic oxidation/C–H functionalization of N-arylpropiolamides by means of gold carbenoids: concise route to 3-acyloxindoles
- (2012) Deyun Qian et al. CHEMICAL COMMUNICATIONS
- Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones
- (2012) Renato Dalpozzo et al. CHEMICAL SOCIETY REVIEWS
- An Organocatalytic Cascade Strategy for the Enantioselective Construction of Spirocyclopentane Bioxindoles Containing Three Contiguous Stereocenters and Two Spiro Quaternary Centers
- (2012) Wangsheng Sun et al. CHEMISTRY-A EUROPEAN JOURNAL
- N-Heterocyclic Carbene-Catalyzed Homoenolate Additions with N-Aryl Ketimines as Electrophiles: Efficient Synthesis of Spirocyclic γ-Lactam Oxindoles
- (2012) Bo Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Diastereodivergent Synthesis of 3-Spirocyclopropyl-2-oxindoles through Direct Enantioselective Cyclopropanation of Oxindoles
- (2012) Xiaowei Dou et al. CHEMISTRY-A EUROPEAN JOURNAL
- Scaffold-Inspired Enantioselective Synthesis of Biologically Important Spiro[pyrrolidin-3,2′-oxindoles] with Structural Diversity through Catalytic Isatin-Derived 1,3-Dipolar Cycloadditions
- (2012) Feng Shi et al. CHEMISTRY-A EUROPEAN JOURNAL
- “Organo-Metal” Synergistic Catalysis: The 1+1>2 Effect for the Construction of Spirocyclopentene Oxindoles
- (2012) Wangsheng Sun et al. CHEMISTRY-A EUROPEAN JOURNAL
- Enantioselective Construction of Spiro[2H-pyran-3,4′-indoline] by a Systematic Michael/Reduction/Cyclization Sequence Triggered by the Asymmetric Conjugate Addition of Ketones to Isatylidenemalononitriles
- (2012) Hua Zhao et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions
- (2012) Bin Wu et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Enantioselective synthesis of 3,3′-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction
- (2012) Wen-Tao Wei et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Access to Spirocyclic Oxindoles via N-Heterocyclic Carbene-Catalyzed Reactions of Enals and Oxindole-Derived α,β-Unsaturated Imines
- (2012) Kun Jiang et al. ORGANIC LETTERS
- Assembly of Spirooxindole Derivatives Containing Four Consecutive Stereocenters via Organocatalytic Michael–Henry Cascade Reactions
- (2012) Klaus Albertshofer et al. ORGANIC LETTERS
- Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione]bisoxindoles and Dispiro[imidazolidine-2-thione]bisoxindoles
- (2012) Yan-Yan Han et al. ORGANIC LETTERS
- Highly enantioselective [4 + 2] annulations catalyzed by amino acid-based phosphines: Synthesis of functionalized cyclohexenes and 3-spirocyclohexene-2-oxindoles
- (2012) Fangrui Zhong et al. Chemical Science
- Synergistic catalysis: A powerful synthetic strategy for new reaction development
- (2012) Anna E. Allen et al. Chemical Science
- An Easy Entry to Optically Active Spiroindolinones: Chiral Brønsted Acid-Catalysed Pictet-Spengler Reactions of Isatins
- (2011) Sara Duce et al. ADVANCED SYNTHESIS & CATALYSIS
- Enantioselective Michael/Cyclization Reaction Sequence: Scaffold-Inspired Synthesis of Spirooxindoles with Multiple Stereocenters
- (2011) Yiming Cao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers
- (2011) Fangrui Zhong et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Catalytic Asymmetric [3+2] Annulation of Allylsilanes with Isatins: Synthesis of Spirooxindoles
- (2011) Nadine V. Hanhan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Dioxindole in Asymmetric Catalytic Synthesis: Routes to Enantioenriched 3-Substituted 3-Hydroxyoxindoles and the Preparation of Maremycin A
- (2011) Giulia Bergonzini et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A highly organocatalytic stereoselective double Michael reaction: efficient construction of optically enriched spirocyclic oxindoles
- (2011) Liang-Liang Wang et al. CHEMICAL COMMUNICATIONS
- Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins
- (2011) Li-Hui Sun et al. CHEMICAL COMMUNICATIONS
- Enantioselective methodologies for the synthesis of spiro compounds
- (2011) Ramon Rios CHEMICAL SOCIETY REVIEWS
- The Marriage of Organocatalysis with Metal Catalysis: Access to Multisubstituted Chiral 2,5-Dihydropyrroles by Cascade Iminium/Enamine-Metal Cooperative Catalysis
- (2011) Wangsheng Sun et al. CHEMISTRY-A EUROPEAN JOURNAL
- Core Structure-Based Design of Organocatalytic [3+2]-Cycloaddition Reactions: Highly Efficient and Stereocontrolled Syntheses of 3,3′-Pyrrolidonyl Spirooxindoles
- (2011) Bin Tan et al. CHEMISTRY-A EUROPEAN JOURNAL
- Organocatalytic Michael-Alkylation Cascade: The Enantioselective Nitrocyclopropanation of Oxindoles
- (2011) Fabio Pesciaioli et al. CHEMISTRY-A EUROPEAN JOURNAL
- Highly Efficient Hydrogen-Bonding Catalysis of the Diels–Alder Reaction of 3-Vinylindoles and Methyleneindolinones Provides Carbazolespirooxindole Skeletons
- (2011) Bin Tan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles
- (2011) Bin Tan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Asymmetric Catalysis of Diels–Alder Reactions with in Situ Generated Heterocyclicortho-Quinodimethanes
- (2011) Yankai Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Trienamines in Asymmetric Organocatalysis: Diels−Alder and Tandem Reactions
- (2011) Zhi-Jun Jia et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters
- (2011) Wen-Bing Chen et al. ORGANIC LETTERS
- Chiral Counteranion Synergistic Organocatalysis under High Temperature: Efficient Construction of Optically Pure Spiro[cyclohexanone-oxindole] Backbone
- (2011) Yu-Bao Lan et al. ORGANIC LETTERS
- Noncovalent Organocatalysis: A Powerful Tool for the Nucleophilic Epoxidation of α-Ylideneoxindoles
- (2011) Chiara Palumbo et al. ORGANIC LETTERS
- Catalytic Asymmetric Construction of Spirocyclopentaneoxindoles by a Combined Ru-Catalyzed Cross-Metathesis/Double Michael Addition Sequence
- (2011) Ying-Mei Li et al. ORGANIC LETTERS
- Tertiary Amine-Catalyzed Chemoselective and Asymmetric [3 + 2] Annulation of Morita–Baylis–Hillman Carbonates of Isatins with Propargyl Sulfones
- (2011) Jing Peng et al. ORGANIC LETTERS
- Highly Regio- and Diastereoselective Construction of Spirocyclopenteneoxindoles through Phosphine-Catalyzed [3 + 2] Annulation of Morita–Baylis–Hillman Carbonates with Isatylidene Malononitriles
- (2011) Hong-Ping Deng et al. ORGANIC LETTERS
- 1,4-Dithiane-2,5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes
- (2011) Nikla Baricordi et al. TETRAHEDRON
- Enantioselective Pictet–Spengler reactions of isatins for the synthesis of spiroindolones
- (2011) Joseph J. Badillo et al. TETRAHEDRON LETTERS
- Organocatalytic enantioselective tandem aldol-cyclization reaction of α-isothiocyanato imides and activated carbonyl compounds
- (2011) Jie Guang et al. TETRAHEDRON-ASYMMETRY
- Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions
- (2011) Shi-Lei Zhang et al. Nature Communications
- Enantioselective Synthesis of Spirocyclic Oxindole-β-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins
- (2010) Xiao-Na Wang et al. ADVANCED SYNTHESIS & CATALYSIS
- Highly organocatalytic asymmetric Michael–ketone aldol–dehydration domino reaction: straightforward approach to construct six-membered spirocyclic oxindoles
- (2010) Liang-Liang Wang et al. CHEMICAL COMMUNICATIONS
- Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction
- (2010) Xavier Companyó et al. CHEMICAL COMMUNICATIONS
- Organocatalytic Tandem Reaction to Construct Six-Membered Spirocyclic Oxindoles with Multiple Chiral Centres through a Formal [2+2+2] Annulation
- (2010) Kun Jiang et al. CHEMISTRY-A EUROPEAN JOURNAL
- An Organocatalytic [3+2] Cyclisation Strategy for the Highly Enantioselective Synthesis of Spirooxindoles
- (2010) Arnaud Voituriez et al. CHEMISTRY-A EUROPEAN JOURNAL
- Synthesis of Aziridine- and Oxirane-2-phosphonates Spiro-Fused with Oxindoles
- (2010) Tecla Gasperi et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Facile Synthesis of 3-Nitro-2-substituted Thiophenes
- (2010) Cornelius J. O’ Connor et al. JOURNAL OF ORGANIC CHEMISTRY
- A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue
- (2010) Xianxing Jiang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products
- (2010) Andrey P. Antonchick et al. Nature Chemistry
- Catalytic asymmetric 1,3-dipolar cycloaddition of N-unprotected 2-oxoindolin-3-ylidene derivatives and azomethine ylides for the construction of spirooxindole-pyrrolidines
- (2010) Tang-Lin Liu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Asymmetric Quadruple Aminocatalytic Domino Reactions to Fused Carbocycles Incorporating a Spirooxindole Motif
- (2010) Kun Jiang et al. ORGANIC LETTERS
- Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3′-oxindoline] Derivatives in High Optical Purity
- (2010) Qiang Wei et al. ORGANIC LETTERS
- Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine
- (2010) Wen-Bing Chen et al. ORGANIC LETTERS
- Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis oftrans-2,3-Dihydrobenzofurans from SalicylN-Thiophosphinyl Imines and Allylic Carbonates
- (2010) Peizhong Xie et al. ORGANIC LETTERS
- Spiroindolones, a Potent Compound Class for the Treatment of Malaria
- (2010) M. Rottmann et al. SCIENCE
- Asymmetric construction of quaternary stereocenters by direct conjugate addition of oxindoles to enone
- (2010) Wangsheng Sun et al. TETRAHEDRON-ASYMMETRY
- Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters
- (2009) Giorgio Bencivenni et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity
- (2009) Xiao-Hua Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Stereoselective Synthesis of Spirooxindoles by Palladium-Catalyzed Decarboxylative Cyclization of γ-Methylidene-δ-valerolactones with Isatins
- (2009) Ryo Shintani et al. ORGANIC LETTERS
- Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products
- (2009) Barry Trost et al. SYNTHESIS-STUTTGART
- Organocatalytic Asymmetric Diels-Alder Reactions of 3-Vinylindoles
- (2008) Claudio Gioia et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct Catalytic Asymmetric Synthesis of Cyclic Aminals from Aldehydes
- (2008) Xu Cheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Phosphine-Catalyzed [3 + 2] Annulation Reaction of Modified Allylic Compounds andN-Tosylimines
- (2008) Suqing Zheng et al. ORGANIC LETTERS
- Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
- (2008) S. Shangary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now