The asymmetric synthesis of CF3-containing spiro[pyrrolidin-3,2′-oxindole] through the organocatalytic 1,3-dipolar cycloaddition reaction

Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO2 and electron-deficient alkynes

(2015) Pavel K. Mykhailiuk   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

(2014) Rishikesh Narayan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Diastereoselective Synthesis of Vicinally Bis(trifluoromethylated) Alkylboron Compounds through Successive Insertions of 2,2,2-Trifluorodiazoethane

(2014) Gary A. Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cascade Multicomponent Synthesis of Indoles, Pyrazoles, and Pyridazinones by Functionalization of Alkenes

(2014) Kiran Matcha et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Triple Relay Catalysis: Enantioselective Synthesis of Spirocyclic Indolines through a One-Pot Process Featuring an Asymmetric 6π Electrocyclization

(2014) Xiao-Ping Yin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

(2014) Javier Adrio et al.   CHEMICAL COMMUNICATIONS

Recent Progress in Direct Introduction of Fluorinated Groups on Alkenes and Alkynes by means of CH Bond Functionalization

(2014) Tatiana Besset et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Catalyzed One-Pot Denitrogenative-Dehydrogenative-Decarboxylative Coupling of β-Ketoacids with Trifluorodiazoethane: Facile Access to Trifluoromethylated Aldol Products

(2014) Heng-Ying Xiong et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Synthesis of CF3-Substituted Pyrazolines/Pyrazoles from Electron-Deficient Alkenes/Alkynes and CF3CHN2Generated in situ: Optimized Synthesis of Tris(trifluoromethyl)pyrazole

(2014) Evgeniy Y. Slobodyanyuk et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-Methylimidazole Promotes the Reaction of Homophthalic Anhydride with Imines

(2014) Jian Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

A Direct Copper-Promoted Three-Component Entry to Trifluoromethylketoximes

(2014) Shuai Wang et al.   ORGANIC LETTERS

Cu(I)-Catalyzed Highly Enantioselective [3 + 3] Cycloaddition between Two Different 1,3-Dipoles, Phthalazinium Dicyanomethanides and Iminoester-Derived Azomethine Ylides

(2014) Chunhao Yuan et al.   ORGANIC LETTERS

Et3N-Catalyzed Tandem Formal [4 + 3] Annulation/Decarboxylation/Isomerization of Methyl Coumalate with Imine Esters: Access to Functionalized Azepine Derivatives

(2014) Kang Liu et al.   ORGANIC LETTERS

Organocatalytic reactions involving nitrogen-ylides

(2014) Kun Jiang et al.   TETRAHEDRON LETTERS

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles

(2013) Liang Hong et al.   ADVANCED SYNTHESIS & CATALYSIS

Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles

(2013) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic asymmetric multicomponent cascade reaction via 1,3-proton shift and [3+2] cycloaddition: an efficient strategy for the synthesis of oxindole derivatives

(2013) Li Tian et al.   CHEMICAL COMMUNICATIONS

3-Isothiocyanato Oxindoles Serving as Powerful and Versatile Precursors to Structurally Diverse Dispirocyclic Thiopyrrolidineoxindoles through a Cascade Michael/Cyclization Process with Amino-Thiocarbamate Catalysts

(2013) Wen-Yong Han et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design, synthesis and QSAR studies of dispiroindole derivatives as new antiproliferative agents

(2013) Riham F. George et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric One-Pot Sequential Mannich/Hydroamination Reaction by Organo- and Gold Catalysts: Synthesis of Spiro[pyrrolidin-3,2′-oxindole] Derivatives

(2013) Xianjie Chen et al.   ORGANIC LETTERS

Asymmetric Catalysis for the Synthesis of Spirocyclic Compounds

(2013) Annaliese K. Franz et al.   ACS Catalysis

Diversity-oriented synthesis of spiro-oxindole-based 2,5-dihydropyrroles via three-component cycloadditions and evaluation on their cytotoxicity

(2013) Wei Tan et al.   RSC Advances

Recent Advances in Diversity Oriented Synthesis through Isatin-based Multicomponent Reactions

(2013) Yunyun Liu et al.   Asian Journal of Organic Chemistry

A Facile Parallel Synthesis of Trifluoroethyl-Substituted Alkynes

(2012) Cui-Bo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted acid-catalyzed diastereo- and enantioselective synthesis of CF3-substituted aziridines

(2012) Zhuo Chai et al.   CHEMICAL COMMUNICATIONS

The highly enantioselective addition of indoles and pyrroles to isatins-derived N-Boc ketimines catalyzed by chiral phosphoric acids

(2012) Jingchao Feng et al.   CHEMICAL COMMUNICATIONS

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Highly Efficient Enantioselective Construction of Bispirooxindoles Containing Three Stereocenters through an Organocatalytic Cascade Michael-Cyclization Reaction

(2012) Hao Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Scaffold-Inspired Enantioselective Synthesis of Biologically Important Spiro[pyrrolidin-3,2′-oxindoles] with Structural Diversity through Catalytic Isatin-Derived 1,3-Dipolar Cycloadditions

(2012) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Michael Addition/Cyclization of Isothiocyanato Oxindoles: Highly Efficient and Versatile Approach for the Synthesis of 3,2′-Pyrrolidinyl Mono- and Bi-spirooxindole Frameworks

(2012) Yi-Ming Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Zinc-Mediated Diastereoselective Synthesis of 3-Amino Oxindoles by Addition of Methyl and Terminal Alkynes to N-tert-Butanesulfinyl Ketimines

(2012) Wenjin Yan et al.   JOURNAL OF ORGANIC CHEMISTRY

A Catalytic Asymmetric Isatin-Involved Povarov Reaction: Diastereo- and Enantioselective Construction of Spiro[indolin-3,2′-quinoline] Scaffold

(2012) Feng Shi et al.   ORGANIC LETTERS

Highly Enantioselective Addition of Enals to Isatin-Derived Ketimines Catalyzed by N-Heterocyclic Carbenes: Synthesis of Spirocyclic γ-Lactams

(2012) Hui Lv et al.   ORGANIC LETTERS

Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles

(2012) Wenjin Yan et al.   ORGANIC LETTERS

Complete 2,5-Diastereocontrol in the Organocatalytic Enantioselective [3+2] Cycloaddition of Enals with Azomethine Ylides Derived from α-Iminocyanoacetates: Asymmetric Synthesis of Pyrrolidines with Four Stereocentres

(2011) Silvia Reboredo et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Trifluoroethyl-Substituted Ketones from Aldehydes and Cyclohexanones

(2011) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

(2011) Javier Adrio et al.   CHEMICAL COMMUNICATIONS

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Enantioselective methodologies for the synthesis of spiro compounds

(2011) Ramon Rios   CHEMICAL SOCIETY REVIEWS

Synthesis and QSAR study of novel cytotoxic spiro[3H-indole-3,2′(1′H)-pyrrolo[3,4-c]pyrrole]-2,3′,5′(1H,2′aH,4′H)-triones

(2011) Adel S. Girgis et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Iron-Catalyzed Preparation of Trifluoromethyl Substituted Vinyl- and Alkynylcyclopropanes

(2011) Bill Morandi et al.   ORGANIC LETTERS

Combination Catalysis in Enantioselective Trifluoromethylation

(2010) Yan Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Cobalt-Catalyzed Preparation of Trifluoromethyl-Substituted Cyclopropanes

(2010) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Cyclopropenation of Alkynes: Synthesis of Trifluoromethyl-Substituted Cyclopropenes

(2010) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide

(2010) Arumugam Thangamani   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New Chiral Ferrocenyl P,S-Ligands for Highly Diastereo-/Enantioselective Catalytic [3 + 2] Cycloaddition of Azomethine Ylides with Cyclic and Acyclic Enones

(2010) Cheng Zhang et al.   ORGANIC LETTERS

Iron-Catalyzed Cyclopropanation with Trifluoroethylamine Hydrochloride and Olefins in Aqueous Media: In Situ Generation of Trifluoromethyl Diazomethane

(2009) Bill Morandi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-Mediated Synthesis of Heterocycles

(2008) Míriam Álvarez-Corral et al.   CHEMICAL REVIEWS

Discovery of Antimycobacterial Spiro-piperidin-4-ones: An Atom Economic, Stereoselective Synthesis, and Biological Intervention

(2008) Raju Ranjith Kumar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS