Imaging of oxygen and hypoxia in cell and tissue samples

Nanoparticle-Based Fluoroionophore for Analysis of Potassium Ion Dynamics in 3D Tissue Models and In Vivo

(2018) Bernhard J. Müller et al.   ADVANCED FUNCTIONAL MATERIALS

Protection of cerebral microcirculation, mitochondrial function, and electrocortical activity by small-volume resuscitation with terlipressin in a rat model of haemorrhagic shock

(2018) K.K. Ida et al.   BRITISH JOURNAL OF ANAESTHESIA

A genetically encoded fluorescent probe for imaging of oxygenation gradients in living Drosophila

(2018) Peter V. Lidsky et al.   DEVELOPMENT

The effects of chemical fixation on the cellular nanostructure

(2017) Yue Li et al.   EXPERIMENTAL CELL RESEARCH

Optical analysis of cellular oxygen sensing

(2017) Katrin Prost-Fingerle et al.   EXPERIMENTAL CELL RESEARCH

Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research

(2017) Trenton L. Place et al.   FREE RADICAL BIOLOGY AND MEDICINE

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

(2017) Hoi-Shan Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Planar implantable sensor for in vivo measurement of cellular oxygen metabolism in brain tissue

(2017) Vassiliy Tsytsarev et al.   JOURNAL OF NEUROSCIENCE METHODS

Oxygen imaging of living cells and tissues using luminescent molecular probes

(2017) Toshitada Yoshihara et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS

Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors

(2017) James R.W. Conway et al.   METHODS

Interrogation of metabolic and oxygen states of tumors with fiber-based luminescence lifetime spectroscopy

(2017) Maria Lukina et al.   OPTICS LETTERS

Oxygen-Sensing Paint-On Bandage

(2017) Pieter G. L. Koolen et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Single-cell time-lapse imaging of intracellular O2 in response to metabolic inhibition and mitochondrial cytochrome-c release

(2017) Heiko Düssmann et al.   Cell Death & Disease

Steering surface topographies of electrospun fibers: understanding the mechanisms

(2017) Gökçe Yazgan et al.   Scientific Reports

A Genetically Encoded FRET Sensor for Hypoxia and Prolyl Hydroxylases

(2016) Suzan Youssef et al.   ACS Chemical Biology

Sulforhodamine Nanothermometer for Multiparametric Fluorescence Lifetime Imaging Microscopy

(2016) James Jenkins et al.   ANALYTICAL CHEMISTRY

Hypoxia and Mucosal Inflammation

(2016) Sean P. Colgan et al.   Annual Review of Pathology-Mechanisms of Disease

The Ca2+/Mn2+-transporting SPCA2 pump is regulated by oxygen and cell density in colon cancer cells

(2016) J. Jenkins et al.   BIOCHEMICAL JOURNAL

Cancer cell aggregate hypoxia visualized in vitro via biocompatible fiber sensors

(2016) Ruipeng Xue et al.   BIOMATERIALS

Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue

(2016) Alexander V. Zhdanov et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bioreductive fluorescent imaging agents: applications to tumour hypoxia

(2016) Robert B. P. Elmes   CHEMICAL COMMUNICATIONS

Correlative NAD(P)H-FLIM and oxygen sensing-PLIM for metabolic mapping

(2016) Sviatlana Kalinina et al.   Journal of Biophotonics

Measurement of pO2 by luminescence lifetime spectroscopy: A comparative study of the phototoxicity and sensitivity of [Ru(Phen)3 ]2+ and PdTCPP in vivo

(2016) Veronika Huntosova et al.   Journal of Biophotonics

Mitochondria-targeted theranostic nanoparticles for optical sensing of oxygen, photodynamic cancer therapy, and assessment of therapeutic efficacy

(2016) Xiao-Hui Wang et al.   MICROCHIMICA ACTA

Use of Fluorescence Lifetime Imaging Microscopy (FLIM) as a Timer of Cell Cycle S Phase

(2016) Irina A. Okkelman et al.   PLoS One

Quantitating the cell: turning images into numbers with ImageJ

(2016) Ellen T Arena et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Versatile Conjugated Polymer Nanoparticles for High-Resolution O2 Imaging in Cells and 3D Tissue Models

(2015) Ruslan I. Dmitriev et al.   ACS Nano

Oxygen-sensing scaffolds for 3-dimensional cell and tissue culture

(2015) James Jenkins et al.   Acta Biomaterialia

Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study

(2015) A. V. Zhdanov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Oxygen-Sensing Methods in Biomedicine from the Macroscale to the Microscale

(2015) Emmanuel Roussakis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tracking Cancer Metastasis In Vivo by Using an Iridium-Based Hypoxia-Activated Optical Oxygen Nanosensor

(2015) Xianchuang Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression

(2015) Alexander V. Zhdanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Luminescent sensing and imaging of oxygen: Fierce competition to the Clark electrode

(2015) Otto S. Wolfbeis   BIOESSAYS

High-resolution in vivo optical imaging of stroke injury and repair

(2015) Sava Sakadžić et al.   BRAIN RESEARCH

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Nanoparticle Probes for the Detection of Cancer Biomarkers, Cells, and Tissues by Fluorescence

(2015) Alyssa B. Chinen et al.   CHEMICAL REVIEWS

Novel uses of fluorescent proteins

(2015) Alexander S Mishin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level

(2015) R. Erapaneedi et al.   EMBO JOURNAL

High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime

(2015) Hiromi Kurokawa et al.   Scientific Reports

Quantitating intracellular oxygen tension in vivo by phosphorescence lifetime measurement

(2015) Yosuke Hirakawa et al.   Scientific Reports

Azo-Based Iridium(III) Complexes as Multicolor Phosphorescent Probes to Detect Hypoxia in 3D Multicellular Tumor Spheroids

(2015) Lingli Sun et al.   Scientific Reports

Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes

(2015) Dmitry E Andreev et al.   GENOME BIOLOGY

Intracellular probes for imaging oxygen concentration: how good are they?

(2015) Ruslan I Dmitriev et al.   Methods and Applications in Fluorescence

Ultrasmall Phosphorescent Polymer Dots for Ratiometric Oxygen Sensing and Photodynamic Cancer Therapy

(2014) Huifang Shi et al.   ADVANCED FUNCTIONAL MATERIALS

Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles

(2014) Ruslan I. Dmitriev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transient state microscopy probes patterns of altered oxygen consumption in cancer cells

(2014) Thiemo Spielmann et al.   FEBS Journal

Correlation Between Intraluminal Oxygen Gradient and Radial Partitioning of Intestinal Microbiota

(2014) Lindsey Albenberg et al.   GASTROENTEROLOGY

Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

(2014) Eric L. Campbell et al.   IMMUNITY

Peptide-Bridged Dinuclear Ru(II) Complex for Mitochondrial Targeted Monitoring of Dynamic Changes to Oxygen Concentration and ROS Generation in Live Mammalian Cells

(2014) Aaron Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modeling the dynamics of hypoxia inducible factor-1α (HIF-1α) within single cells and 3D cell culture systems

(2014) Joseph Leedale et al.   MATHEMATICAL BIOSCIENCES

Direct measurement of local oxygen concentration in the bone marrow of live animals

(2014) Joel A. Spencer et al.   NATURE

Wide-field time-correlated single-photon counting (TCSPC) lifetime microscopy with microsecond time resolution

(2014) Liisa M. Hirvonen et al.   OPTICS LETTERS

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

(2014) C. Loenarz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-invasive transdermal two-dimensional mapping of cutaneous oxygenation with a rapid-drying liquid bandage

(2014) Zongxi Li et al.   Biomedical Optics Express

Luminescent Dual Sensors Reveal Extracellular pH-Gradients and Hypoxia on Chronic Wounds That Disrupt Epidermal Repair

(2014) Stephan Schreml et al.   Theranostics

Small molecule phosphorescent probes for O2 imaging in 3D tissue models

(2014) Ruslan I. Dmitriev et al.   Biomaterials Science

Measuring Mitochondrial Oxygen Tension

(2013) Egbert G. Mik   ANESTHESIA AND ANALGESIA

Imaging challenges in biomaterials and tissue engineering

(2013) Alyssa A. Appel et al.   BIOMATERIALS

Imaging of neurosphere oxygenation with phosphorescent probes

(2013) Ruslan I. Dmitriev et al.   BIOMATERIALS

Biological detection by optical oxygen sensing

(2013) Dmitri B. Papkovsky et al.   CHEMICAL SOCIETY REVIEWS

Recent progress in the development of near-infrared fluorescent probes for bioimaging applications

(2013) Zhiqian Guo et al.   CHEMICAL SOCIETY REVIEWS

Identifying HIF Activity in Three-Dimensional Cultures of Islet-Like Clusters

(2013) Matthew L. Skiles et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

In vivo imaging of brain metabolism activity using a phosphorescent oxygen-sensitive probe

(2013) Vassiliy Tsytsarev et al.   JOURNAL OF NEUROSCIENCE METHODS

The Biomechanical Effect of Corneal Collagen Cross-Linking (CXL) With Riboflavin and UV-A is Oxygen Dependent

(2013) Olivier Richoz et al.   Translational Vision Science & Technology

A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities

(2012) Alina V. Kondrashina et al.   ADVANCED FUNCTIONAL MATERIALS

Assessment of Cellular Oxygen Gradients with a Panel of Phosphorescent Oxygen-Sensitive Probes

(2012) Ruslan I. Dmitriev et al.   ANALYTICAL CHEMISTRY

Real-time determination of intracellular oxygen in bacteria using a genetically encoded FRET-based biosensor

(2012) Janko Potzkei et al.   BMC BIOLOGY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Optical probes and techniques for O2 measurement in live cells and tissue

(2012) Ruslan I. Dmitriev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Complexes of IrIII-Octaethylporphyrin with Peptides as Probes for Sensing Cellular O2

(2012) Klaus Koren et al.   CHEMBIOCHEM

Real-time,in vivomeasurement of tissular pO2 through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy

(2012) Filippo Piffaretti et al.   JOURNAL OF BIOMEDICAL OPTICS

Frontiers in Optical Imaging of Cerebral Blood Flow and Metabolism

(2012) Anna Devor et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ultra-Small, Highly Stable, and Sensitive Dual Nanosensors for Imaging Intracellular Oxygen and pH in Cytosol

(2012) Xu-dong Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cutaneous respirometry by dynamic measurement of mitochondrial oxygen tension for monitoring mitochondrial function in vivo

(2012) Floor A. Harms et al.   MITOCHONDRION

Immunolabeling artifacts and the need for live-cell imaging

(2012) Ulrike Schnell et al.   NATURE METHODS

Frequency-multiplexed in vivo multiphoton phosphorescence lifetime microscopy

(2012) Scott S. Howard et al.   Nature Photonics

A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications

(2012) Michelle L. James et al.   PHYSIOLOGICAL REVIEWS

Intracellular O2 Sensing Probe Based on Cell-Penetrating Phosphorescent Nanoparticles

(2011) Andreas Fercher et al.   ACS Nano

Two New “Protected” Oxyphors for Biological Oximetry: Properties and Application in Tumor Imaging

(2011) Tatiana V. Esipova et al.   ANALYTICAL CHEMISTRY

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Cell-Penetrating Conjugates of Coproporphyrins with Oligoarginine Peptides: Rational Design and Application for Sensing Intracellular O2

(2011) Ruslan I. Dmitriev et al.   BIOCONJUGATE CHEMISTRY

A review of NIR dyes in cancer targeting and imaging

(2011) Shenglin Luo et al.   BIOMATERIALS

2D luminescence imaging of physiological wound oxygenation

(2011) Stephan Schreml et al.   EXPERIMENTAL DERMATOLOGY

Correlating hypoxia with insulin secretion using a fluorescent hypoxia detection system

(2011) Matthew L. Skiles et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels

(2011) Jérôme Lecoq et al.   NATURE MEDICINE

Microscopy in 3D: a biologist's toolbox

(2011) Robert S. Fischer et al.   TRENDS IN CELL BIOLOGY

Imaging of oxygen gradients in monolayer cultured cells using green fluorescent protein

(2010) Eiji Takahashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Oxygen in acute and chronic wound healing

(2010) S. Schreml et al.   BRITISH JOURNAL OF DERMATOLOGY

Phosphorescent Light–Emitting Iridium Complexes Serve as a Hypoxia-Sensing Probe for Tumor Imaging in Living Animals

(2010) Shaojuan Zhang et al.   CANCER RESEARCH

Multiple fluorescent chemical sensing and imaging

(2010) Matthias I. J. Stich et al.   CHEMICAL SOCIETY REVIEWS

Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor

(2010) Ruslan I. Dmitriev et al.   FEBS Journal

Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique

(2010) Alexander V. Zhdanov et al.   Integrative Biology

Retinal Tissue Oxygen Tension Imaging in the Rat

(2010) M. Shahidi et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue

(2010) Sava Sakadžić et al.   NATURE METHODS

Fluorescent Proteins and Their Applications in Imaging Living Cells and Tissues

(2010) Dmitriy M. Chudakov et al.   PHYSIOLOGICAL REVIEWS

Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides

(2009) Ruslan I. Dmitriev et al.   ANALYTICAL BIOCHEMISTRY

Live-cell microscopy - tips and tools

(2009) M. M. Frigault et al.   JOURNAL OF CELL SCIENCE

Mitochondrial oxygen tension within the heart

(2009) Egbert G. Mik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Design of metalloporphyrin-based dendritic nanoprobes for two-photon microscopy of oxygen

(2009) Artem Y. Lebedev et al.   JOURNAL OF PORPHYRINS AND PHTHALOCYANINES

Po2 measurements in the microcirculation using phosphorescence quenching microscopy at high magnification

(2008) Aleksander S. Golub et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

In Vivo Mitochondrial Oxygen Tension Measured by a Delayed Fluorescence Lifetime Technique

(2008) Egbert G. Mik et al.   BIOPHYSICAL JOURNAL

Oxygen Microscopy by Two-Photon-Excited Phosphorescence

(2008) Olga S. Finikova et al.   CHEMPHYSCHEM

Molecular Imaging of Hypoxia

(2008) K. A. Krohn et al.   JOURNAL OF NUCLEAR MEDICINE

Transcutaneous pO2imaging during tourniquet-induced forearm ischemia using planar optical oxygen sensors

(2008) Philipp Babilas et al.   SKIN RESEARCH AND TECHNOLOGY