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Title
Regulating the human HECT E3 ligases
Authors
Keywords
-
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-06-01
DOI
10.1007/s00018-018-2848-2
References
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- (2018) Sonja Lorenz BIOLOGICAL CHEMISTRY
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- (2017) Zan Chen et al. MOLECULAR CELL
- The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness
- (2017) Amrita Singh Chandhoke et al. Oncotarget
- A conformational switch regulates the ubiquitin ligase HUWE1
- (2017) Bodo Sander et al. eLife
- The Nedd8 Non-covalent Binding Region in the Smurf HECT Domain is Critical to its Ubiquitn Ligase Function
- (2017) Shan He et al. Scientific Reports
- Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation
- (2016) Jingyi Shu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- E2 enzymes: more than just middle men
- (2016) Mikaela D Stewart et al. CELL RESEARCH
- Ubiquitin modifications
- (2016) Kirby N Swatek et al. CELL RESEARCH
- Functional and pathological relevance of HERC family proteins: a decade later
- (2016) Susana Sánchez-Tena et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Itch promotes the neddylation of JunB and regulates JunB-dependent transcription
- (2016) Haiwen Li et al. CELLULAR SIGNALLING
- Trip12 is an E3 ubiquitin ligase for USP7/HAUSP involved in the DNA damage response
- (2016) Xiaoliang Liu et al. FEBS LETTERS
- ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding
- (2016) Ziying Han et al. JOURNAL OF VIROLOGY
- System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes
- (2016) Wei Zhang et al. MOLECULAR CELL
- Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53
- (2016) Denise Martinez-Zapien et al. NATURE
- Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity
- (2016) Nicolas Huguenin-Dezot et al. Cell Reports
- Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin
- (2016) Eunju Im et al. Open Biology
- Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential
- (2016) Miranda Thomas et al. PLoS Pathogens
- An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A
- (2015) Jason J. Yi et al. CELL
- The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial–mesenchymal transition in a sumoylation-regulated manner
- (2015) A S Chandhoke et al. CELL DEATH AND DIFFERENTIATION
- Expanding the ubiquitin code through post-translational modification
- (2015) L. Herhaus et al. EMBO REPORTS
- Ubiquitin-specific protease 7 accelerates p14ARFdegradation by deubiquitinating thyroid hormone receptor-interacting protein 12 and promotes hepatocellular carcinoma progression
- (2015) Jia-Bin Cai et al. HEPATOLOGY
- Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation
- (2015) Christopher Riling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism
- (2015) Stefan G. Kathman et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Protein neddylation: beyond cullin–RING ligases
- (2015) Radoslav I. Enchev et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death
- (2015) C K Lee et al. ONCOGENE
- Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination
- (2015) Franziska Mortensen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy
- (2015) Ketaki Ganti et al. Viruses-Basel
- Identification and Characterization of Small Molecule Human Papillomavirus E6 Inhibitors
- (2014) Kimberly A. Malecka et al. ACS Chemical Biology
- Neutron-Encoded Mass Signatures for Quantitative Top-Down Proteomics
- (2014) Timothy W. Rhoads et al. ANALYTICAL CHEMISTRY
- Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8
- (2014) Daniel C. Scott et al. CELL
- Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses
- (2014) Z. Han et al. JOURNAL OF VIROLOGY
- Autoregulation of the 26S proteasome by in situ ubiquitination
- (2014) Andrew D. Jacobson et al. MOLECULAR BIOLOGY OF THE CELL
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- The contribution of de novo coding mutations to autism spectrum disorder
- (2014) Ivan Iossifov et al. NATURE
- Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity
- (2014) A. Persaud et al. Science Signaling
- Structural Basis of the Activation and Degradation Mechanisms of the E3 Ubiquitin Ligase Nedd4L
- (2014) Albert Escobedo et al. STRUCTURE
- The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis
- (2014) Ping Xie et al. Nature Communications
- c-Abl Phosphorylates E6AP and Regulates Its E3 Ubiquitin Ligase Activity
- (2013) Ai-Leen Chan et al. BIOCHEMISTRY
- RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
- (2013) Meredith B. Metzger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mammalian HECT ubiquitin-protein ligases: Biological and pathophysiological aspects
- (2013) Martin Scheffner et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Building and remodelling Cullin-RING E3 ubiquitin ligases
- (2013) John R Lydeard et al. EMBO REPORTS
- Development of inhibitors in the ubiquitination cascade
- (2013) Wei Zhang et al. FEBS LETTERS
- The Active Form of E6-associated protein (E6AP)/UBE3A Ubiquitin Ligase Is an Oligomer
- (2013) Virginia P. Ronchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins
- (2013) K. Zanier et al. SCIENCE
- Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
- (2013) Hari B Kamadurai et al. eLife
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
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- (2012) Jason Howitt et al. JOURNAL OF CELL BIOLOGY
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- (2012) B. Todorovic et al. JOURNAL OF VIROLOGY
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- (2012) Diede Oudshoorn et al. PLoS One
- Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions
- (2012) D. Y.-w. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2012) Eric Aragón et al. STRUCTURE
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- (2011) Ian Walsh et al. BIOINFORMATICS
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- (2011) Hyung Cheol Kim et al. EMBO REPORTS
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- (2011) Maoyuan Tian et al. FEBS LETTERS
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- (2011) Simone Kühnle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A
- (2011) Alexander Lemak et al. JOURNAL OF BIOMOLECULAR NMR
- Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD
- (2011) V. Tomaic et al. JOURNAL OF VIROLOGY
- Cdh1 Is a HECT of an Activator
- (2011) Luying Jia et al. MOLECULAR CELL
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- (2011) Lixin Wan et al. MOLECULAR CELL
- WWP2 is an E3 ubiquitin ligase for PTEN
- (2011) Subbareddy Maddika et al. NATURE CELL BIOLOGY
- Interferon-Stimulated Gene 15 and the Protein ISGylation System
- (2010) Dongxian Zhang et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses
- (2010) Delin Chen et al. NATURE
- The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases
- (2010) Cheol-Sang Hwang et al. NATURE CELL BIOLOGY
- Regulation of the RSP5 Ubiquitin Ligase by an Intrinsic Ubiquitin-binding Site
- (2009) Michael E. French et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Ubiquitin Binding Region of the Smurf HECT Domain Facilitates Polyubiquitylation and Binding of Ubiquitylated Substrates
- (2009) Abiodun A. Ogunjimi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity
- (2009) H. C. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
- (2009) Hari B. Kamadurai et al. MOLECULAR CELL
- Itch self-polyubiquitylation occurs through lysine-63 linkages
- (2008) Flavia Scialpi et al. BIOCHEMICAL PHARMACOLOGY
- HPV E6, E6AP and cervical cancer
- (2008) Sylvie Beaudenon et al. BMC BIOCHEMISTRY
- The ubiquitin system, disease, and drug discovery
- (2008) Matthew D Petroski BMC BIOCHEMISTRY
- Tenets of PTEN Tumor Suppression
- (2008) Leonardo Salmena et al. CELL
- ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response
- (2008) Oxana A. Malakhova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity
- (2008) A. Okumura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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