The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases

The arginylation-dependent association of calreticulin with stress granules is regulated by calcium

(2010) Marcos A. Carpio et al.   BIOCHEMICAL JOURNAL

Ubiquitin Chain Elongation Enzyme Ufd2 Regulates a Subset of Doa10 Substrates

(2010) Chang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nucleus-based Quality Control Mechanism for Cytosolic Proteins

(2010) Rupali Prasad et al.   MOLECULAR BIOLOGY OF THE CELL

Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins

(2010) Nadinath B. Nillegoda et al.   MOLECULAR BIOLOGY OF THE CELL

A Dual E3 Mechanism for Rub1 Ligation to Cdc53

(2010) Daniel C. Scott et al.   MOLECULAR CELL

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases

(2010) Woo Suk Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of substrate recognition and specificity in the N-end rule pathway

(2010) Edna Matta-Camacho et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The molecular principles of N-end rule recognition

(2010) Shashikanth M Sriram et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome

(2010) D. Zaaroor-Regev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Multitasking with ubiquitin through multivalent interactions

(2010) Fen Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

The plant N-end rule pathway: structure and functions

(2010) Emmanuelle Graciet et al.   TRENDS IN PLANT SCIENCE

Arginylation-Dependent Neural Crest Cell Migration Is Essential for Mouse Development

(2010) Satoshi Kurosaka et al.   PLoS Genetics

Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation

(2009) Ping Xu et al.   CELL

Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway

(2009) Haiqing Wang et al.   MOLECULAR CELL

ClpS is the recognition component forEscherichia colisubstrates of the N-end rule degradation pathway

(2009) Ronny Schmidt et al.   MOLECULAR MICROBIOLOGY

Origin and function of ubiquitin-like proteins

(2009) Mark Hochstrasser   NATURE

Ablation of Arginylation in the Mouse N-End Rule Pathway: Loss of Fat, Higher Metabolic Rate, Damaged Spermatogenesis, and Neurological Perturbations

(2009) Christopher S. Brower et al.   PLoS One

Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase

(2009) C.-S. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis of substrate selection by the N-end rule adaptor protein ClpS

(2009) G. Roman-Hernandez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

(2009) J. W. Heck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1

(2008) Frederik Eisele et al.   FEBS LETTERS

Discovery of Cellular Regulation by Protein Degradation

(2008) Alexander Varshavsky   JOURNAL OF BIOLOGICAL CHEMISTRY

The Substrate Recognition Domains of the N-end Rule Pathway

(2008) Takafumi Tasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway

(2008) Zanxian Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino Acids Induce Peptide Uptake via Accelerated Degradation of CUP9, the Transcriptional Repressor of the PTR2 Peptide Transporter

(2008) Zanxian Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HECT Domain of TRIP12 Ubiquitinates Substrates of the Ubiquitin Fusion Degradation Pathway

(2008) Yoon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11

(2008) C Chen et al.   ONCOGENE

Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway

(2008) C.-S. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA