The Active Form of E6-associated protein (E6AP)/UBE3A Ubiquitin Ligase Is an Oligomer

Behavioral deficits in an Angelman syndrome model: Effects of genetic background and age

(2013) Hsien-Sung Huang et al.   BEHAVIOURAL BRAIN RESEARCH

c-Abl Phosphorylates E6AP and Regulates Its E3 Ubiquitin Ligase Activity

(2013) Ai-Leen Chan et al.   BIOCHEMISTRY

Tripartite Motif Ligases Catalyze Polyubiquitin Chain Formation through a Cooperative Allosteric Mechanism

(2013) Frederick C. Streich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E6AP/UBE3A Ubiquitin Ligase Harbors Two E2∼ubiquitin Binding Sites

(2013) Virginia P. Ronchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic Factors and Autism Spectrum Disorders

(2013) Bess M. Flashner et al.   NEUROMOLECULAR MEDICINE

Role of the ubiquitin ligase E6AP/UBE3A in controlling levels of the synaptic protein Arc

(2013) S. Kuhnle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

(2013) K. Zanier et al.   SCIENCE

Evolution of oligomeric state through geometric coupling of protein interfaces

(2012) T. Perica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between E6AP and E6 proteins from alpha and beta HPV types

(2012) Miranda Thomas et al.   VIROLOGY

E6*, the 50 Amino Acid Product of the Most Abundant Spliced Transcript of the E6 Oncoprotein in High-Risk Human Papillomavirus, Is a Promiscuous Folder and Binder

(2011) Angeles Heer et al.   BIOCHEMISTRY

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

(2011) Elena Maspero et al.   EMBO REPORTS

Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders

(2011) C. P. Schaaf et al.   HUMAN MOLECULAR GENETICS

E1-E2 Interactions in Ubiquitin and Nedd8 Ligation Pathways

(2011) Zeynep Tokgöz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Gene Dosage of Ube3a Results in Autism Traits and Decreased Glutamate Synaptic Transmission in Mice

(2011) S. E. P. Smith et al.   Science Translational Medicine

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

(2011) Angela M. Mabb et al.   TRENDS IN NEUROSCIENCES

FoxM1B Regulates NEDD4-1 Expression, Leading to Cellular Transformation and Full Malignant Phenotype in Immortalized Human Astrocytes

(2010) Bingbing Dai et al.   CANCER RESEARCH

Cutaneous Papillomavirus E6 Proteins Must Interact with p300 and Block p53-Mediated Apoptosis for Cellular Immortalization and Tumorigenesis

(2010) P. Muench et al.   CANCER RESEARCH

EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

(2010) Seth S. Margolis et al.   CELL

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

(2010) Paul L. Greer et al.   CELL

Angelman syndrome: advancing the research frontier of neurodevelopmental disorders

(2010) Benjamin D. Philpot et al.   Journal of Neurodevelopmental Disorders

Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a

(2010) M. Sato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Koilocytes indicate a role for human papilloma virus in breast cancer

(2009) J S Lawson et al.   BRITISH JOURNAL OF CANCER

The Ubiquitin Binding Region of the Smurf HECT Domain Facilitates Polyubiquitylation and Binding of Ubiquitylated Substrates

(2009) Abiodun A. Ogunjimi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities

(2009) Renuka K. Pandya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants of Stability for the E6 Protein of Papillomavirus Type 16

(2009) Yuqi Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

E6 Proteins from Diverse Papillomaviruses Self-Associate Both In Vitro and In Vivo

(2009) Katia Zanier et al.   JOURNAL OF MOLECULAR BIOLOGY

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

(2009) Hari B. Kamadurai et al.   MOLECULAR CELL

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

(2009) Joseph T. Glessner et al.   NATURE

Ube3a is required for experience-dependent maturation of the neocortex

(2009) Koji Yashiro et al.   NATURE NEUROSCIENCE

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin ligase E6-AP and its role in human disease

(2008) Konstantin Matentzoglu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

HPV E6, E6AP and cervical cancer

(2008) Sylvie Beaudenon et al.   BMC BIOCHEMISTRY

Catalytically Active Monomer of GlutathioneS-Transferase π and Key Residues Involved in the Electrostatic Interaction between Subunits

(2008) Yu-chu Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY