A 5′ AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma

Autophagy Induced by Areca Nut Extract Contributes to Decreasing Cisplatin Toxicity in Oral Squamous Cell Carcinoma Cells: Roles of Reactive Oxygen Species/AMPK Signaling

(2017) Zhi Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prognostic significance of extracapsular spread of lymph node metastasis from oral squamous cell carcinoma in the clinically negative neck

(2017) P. Suton et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

Metformin induces cell cycle arrest at the G1 phase through E2F8 suppression in lung cancer cells

(2017) Dong Hao Jin et al.   Oncotarget

Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy

(2017) Yongbin Wang et al.   EBioMedicine

Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A

(2017) Chang-Han Chen et al.   Scientific Reports

FTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism

(2017) Li-Yuan Bai et al.   Scientific Reports

Role of autophagy-related protein expression in patients with rectal cancer treated with neoadjuvant chemoradiotherapy

(2016) Byoung Yong Shim et al.   BMC CANCER

Metformin inhibits JAK2V617F activity in MPN cells by activating AMPK and PP2A complexes containing the B56α subunit

(2016) Ichiro Kawashima et al.   EXPERIMENTAL HEMATOLOGY

Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma

(2016) KOJI HARADA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

PGC-1α, glucose metabolism and type 2 diabetes mellitus

(2016) Haijiang Wu et al.   JOURNAL OF ENDOCRINOLOGY

Global Epidemiology of Head and Neck Cancers: A Continuing Challenge

(2016) Bhawna Gupta et al.   ONCOLOGY

Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro

(2016) ZHEN-YUAN GAO et al.   Experimental and Therapeutic Medicine

Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis

(2016) Xiaofeng Qi et al.   Scientific Reports

Pharmacological exploitation of the phenothiazine antipsychotics to develop novel antitumor agents–A drug repurposing strategy

(2016) Chia-Hsien Wu et al.   Scientific Reports

Overexpression of pyruvate kinase M2 associates with aggressive clinicopathological features and unfavorable prognosis in oral squamous cell carcinoma

(2015) Yanling Wang et al.   CANCER BIOLOGY & THERAPY

Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators

(2015) Eman M. E. Dokla et al.   ChemMedChem

Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis

(2015) Hee-sun Moon et al.   MOLECULAR CARCINOGENESIS

Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism

(2015) Seung Min Jeong et al.   MOLECULES AND CELLS

Role of AMP-Activated Protein Kinase in Cancer Therapy

(2014) Gauhar Rehman et al.   ARCHIV DER PHARMAZIE

Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice

(2014) Weidong Li et al.   MOLECULAR CARCINOGENESIS

Metformin Induces Apoptosis and Cell Cycle Arrest Mediated by Oxidative Stress, AMPK and FOXO3a in MCF-7 Breast Cancer Cells

(2014) Eveline A. I. F. Queiroz et al.   PLoS One

Free Radicals in Cross Talk Between Autophagy and Apoptosis

(2013) Vitaliy O. Kaminskyy et al.   ANTIOXIDANTS & REDOX SIGNALING

Cancer as a metabolic disease: implications for novel therapeutics

(2013) T. N. Seyfried et al.   CARCINOGENESIS

Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma

(2013) L. Zheng et al.   CLINICAL CANCER RESEARCH

AMP-Activated Protein Kinase Induces p53 by Phosphorylating MDMX and Inhibiting Its Activity

(2013) G. He et al.   MOLECULAR AND CELLULAR BIOLOGY

Histological evaluation of AMPK signalling in primary breast cancer

(2009) Sirwan M Hadad et al.   BMC CANCER