Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators

AMPK as a Potential Anticancer Target - Friend or Foe?

(2015) Hsiao-Ching Chuang et al.   CURRENT PHARMACEUTICAL DESIGN

AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt–MDM2–Foxo3a Signaling Axis

(2014) Chih-Chien Chou et al.   CANCER RESEARCH

Small Molecule Adenosine 5′-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases

(2014) Sandeep Rana et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

(2014) William W Wheaton et al.   eLife

PAINS: Relevance to Tool Compound Discovery and Fragment-Based Screening

(2013) Jonathan B. Baell et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators

(2013) Li-Fang Yu et al.   ACS Medicinal Chemistry Letters

Direct AMP-activated protein kinase activators: a review of evidence from the patent literature

(2012) Fabrizio Giordanetto et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Computer-Aided Drug Design for AMP-Activated Protein Kinase Activators

(2011) Zhanli Wang et al.   Current Computer-Aided Drug Design

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

(2011) Kuen-Haur Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators

(2010) Jih-Hwa Guh et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

AMPK as a mediator of hormonal signalling

(2009) Chung Thong Lim et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Small Molecule Antagonizes Autoinhibition and Activates AMP-activated Protein Kinase in Cells

(2008) Tao Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY