Tools for translation: non-viral materials for therapeutic mRNA delivery
Published 2017 View Full Article
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Title
Tools for translation: non-viral materials for therapeutic mRNA delivery
Authors
Keywords
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Journal
Nature Reviews Materials
Volume 2, Issue 10, Pages 17056
Publisher
Springer Nature
Online
2017-09-12
DOI
10.1038/natrevmats.2017.56
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Note: Only part of the references are listed.- Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides
- (2017) Manuela Chiper et al. JOURNAL OF CONTROLLED RELEASE
- A Targeted and Stable Polymeric Nanoformulation Enhances Systemic Delivery of mRNA to Tumors
- (2017) Qixian Chen et al. MOLECULAR THERAPY
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
- (2017) X. Luo et al. Nanoscale
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination
- (2017) Norbert Pardi et al. NATURE
- Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals
- (2017) Colin J. McKinlay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic delivery of factor IX messenger RNA for protein replacement therapy
- (2017) Suvasini Ramaswamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modified mRNA for BMP-2 in Combination with Biomaterials Serves as a Transcript-Activated Matrix for Effectively Inducing Osteogenic Pathways in Stem Cells
- (2017) Elizabeth R. Balmayor et al. STEM CELLS AND DEVELOPMENT
- Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
- (2017) Norbert Pardi et al. Nature Communications
- CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells
- (2017) Levi J. Rupp et al. Scientific Reports
- siRNA Delivery Strategies: A Comprehensive Review of Recent Developments
- (2017) Katyayani Tatiparti et al. Nanomaterials
- The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery
- (2016) Xinwei Cheng et al. ADVANCED DRUG DELIVERY REVIEWS
- Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
- (2016) Owen S. Fenton et al. ADVANCED MATERIALS
- A Single Methylene Group in Oligoalkylamine-Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery
- (2016) Anita Jarzębińska et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA
- (2016) Jason B. Miller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety
- (2016) Satoshi Uchida et al. BIOMATERIALS
- CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells
- (2016) Xiaojuan Liu et al. CELL RESEARCH
- Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition
- (2016) Jiangtao Ren et al. CLINICAL CANCER RESEARCH
- Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
- (2016) F DeRosa et al. GENE THERAPY
- Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?
- (2016) Marina Cavazzana et al. HUMAN GENE THERAPY
- Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration
- (2016) Zohreh Sadat Badieyan et al. JOURNAL OF CONTROLLED RELEASE
- Enhanced intranasal delivery of mRNA vaccine by overcoming the nasal epithelial barrier via intra- and paracellular pathways
- (2016) Man Li et al. JOURNAL OF CONTROLLED RELEASE
- Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells
- (2016) Hye Yeon Choi et al. JOURNAL OF CONTROLLED RELEASE
- Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles
- (2016) Chin-Yu Lin et al. JOURNAL OF CONTROLLED RELEASE
- Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo
- (2016) Yizhou Dong et al. NANO LETTERS
- Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
- (2016) Matthias A. Oberli et al. NANO LETTERS
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Generation of knockout mice by Cpf1-mediated gene targeting
- (2016) Yongsub Kim et al. NATURE BIOTECHNOLOGY
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- Epigenetic mechanisms in neurogenesis
- (2016) Bing Yao et al. NATURE REVIEWS NEUROSCIENCE
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment
- (2016) Hailati Aini et al. Scientific Reports
- Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon
- (2016) Katrijn Broos et al. Molecular Therapy-Nucleic Acids
- Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
- (2015) Bernd Zetsche et al. CELL
- Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles
- (2015) Miyuki Baba et al. JOURNAL OF CONTROLLED RELEASE
- N 1 -methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
- (2015) Oliwia Andries et al. JOURNAL OF CONTROLLED RELEASE
- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
- (2015) Norbert Pardi et al. JOURNAL OF CONTROLLED RELEASE
- Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
- (2015) Andreas Thess et al. MOLECULAR THERAPY
- An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo
- (2015) Bin Li et al. NANO LETTERS
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
- (2015) Anders Wittrup et al. NATURE BIOTECHNOLOGY
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- (2015) Akitsugu Matsui et al. Scientific Reports
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- (2015) E. Hattinger et al. Journal of Immunology Research
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- (2015) Masakazu Hashimoto et al. Scientific Reports
- Antibody-modified T cells: CARs take the front seat for hematologic malignancies
- (2014) M. V. Maus et al. BLOOD
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines
- (2014) Raquel P Deering et al. Expert Opinion on Drug Delivery
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- (2014) Patrick Midoux et al. Expert Review of Vaccines
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- (2014) Hyeshik Chang et al. MOLECULAR CELL
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- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
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- (2014) Ugur Sahin et al. NATURE REVIEWS DRUG DISCOVERY
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- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
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- (2014) Bettina L. Lee et al. TRENDS IN CELL BIOLOGY
- Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
- (2014) Kathryn A. Whitehead et al. Nature Communications
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- (2013) David M. Barrett et al. HUMAN GENE THERAPY
- Adoptive T Cell Transfer for Cancer Immunotherapy in the Era of Synthetic Biology
- (2013) Michael Kalos et al. IMMUNITY
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- (2013) Meenakshi Hegde et al. MOLECULAR THERAPY
- Single-cell mRNA transfection studies: Delivery, kinetics and statistics by numbers
- (2013) Carolin Leonhardt et al. Nanomedicine-Nanotechnology Biology and Medicine
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
- (2013) Lior Zangi et al. NATURE BIOTECHNOLOGY
- Efficient genome editing in zebrafish using a CRISPR-Cas system
- (2013) Woong Y Hwang et al. NATURE BIOTECHNOLOGY
- Reprogramming human fibroblasts to pluripotency using modified mRNA
- (2013) Pankaj K Mandal et al. Nature Protocols
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Toxicity profiling of several common RNAi-based nanomedicines: a comparative study
- (2013) Dalit Landesman-Milo et al. Drug Delivery and Translational Research
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis, Characterization, and Evaluation of Ionizable Lysine-Based Lipids for siRNA Delivery
- (2012) Colin L. Walsh et al. BIOCONJUGATE CHEMISTRY
- Virus-mediated gene delivery for human gene therapy
- (2012) Mauro Giacca et al. JOURNAL OF CONTROLLED RELEASE
- CD64 Expression Distinguishes Monocyte-Derived and Conventional Dendritic Cells and Reveals Their Distinct Role during Intramuscular Immunization
- (2012) C. Langlet et al. JOURNAL OF IMMUNOLOGY
- Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin
- (2012) Katalin Karikó et al. MOLECULAR THERAPY
- RNA-guided genetic silencing systems in bacteria and archaea
- (2012) Blake Wiedenheft et al. NATURE
- Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection
- (2012) Benjamin Petsch et al. NATURE BIOTECHNOLOGY
- Developing mRNA-vaccine technologies
- (2012) Thomas Schlake et al. RNA Biology
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells
- (2011) David M. Barrett et al. HUMAN GENE THERAPY
- Immune Signaling by RIG-I-like Receptors
- (2011) Yueh-Ming Loo et al. IMMUNITY
- Design of multifunctional non-viral gene vectors to overcome physiological barriers: Dilemmas and strategies
- (2011) Tao Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nanoparticle PEGylation for imaging and therapy
- (2011) Jesse V Jokerst et al. Nanomedicine
- Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
- (2011) Federico Perche et al. Nanomedicine-Nanotechnology Biology and Medicine
- Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
- (2011) Michael S D Kormann et al. NATURE BIOTECHNOLOGY
- Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
- (2011) Katalin Karikó et al. NUCLEIC ACIDS RESEARCH
- Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway
- (2011) Christina Lorenz et al. RNA Biology
- Targeted Genome Editing Across Species Using ZFNs and TALENs
- (2011) Andrew J. Wood et al. SCIENCE
- Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database
- (2011) George A. Khoury et al. Scientific Reports
- A Role for Codon Order in Translation Dynamics
- (2010) Gina Cannarozzi et al. CELL
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- mRNA transfection of cervical carcinoma and mesenchymal stem cells mediated by cationic carriers
- (2010) Joanna Rejman et al. JOURNAL OF CONTROLLED RELEASE
- Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
- (2010) Bart R. Anderson et al. NUCLEIC ACIDS RESEARCH
- The Many Pathways of RNA Degradation
- (2009) Jonathan Houseley et al. CELL
- Progress and prospects: immune responses to viral vectors
- (2009) S Nayak et al. GENE THERAPY
- Immunize and disappear—Safety-optimized mRNA vaccination with a panel of 29 allergens
- (2009) Elisabeth Roesler et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model
- (2008) S H Yoon et al. CANCER GENE THERAPY
- Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells
- (2008) L. V. Sharova et al. DNA RESEARCH
- Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles
- (2008) Frank Alexis et al. MOLECULAR PHARMACEUTICS
- Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
- (2008) Katalin Karikó et al. MOLECULAR THERAPY
- Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
- (2008) Yannick Doyon et al. NATURE BIOTECHNOLOGY
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