- Home
- Publications
- Publication Search
- Publication Details
Title
Dengue Virus Non-Structural Protein 5
Authors
Keywords
-
Journal
Viruses-Basel
Volume 9, Issue 4, Pages 91
Publisher
MDPI AG
Online
2017-04-25
DOI
10.3390/v9040091
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors
- (2017) Akkaladevi Venkatesham et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design
- (2017) Fatiha Benmansour et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors
- (2017) Hong-Tao Xu et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Triphosphate Reorientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA Polymerases
- (2017) Xiaorong Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The uncoupling of catalysis and translocation in the viral RNA-dependent RNA polymerase
- (2017) Bo Shu et al. RNA Biology
- The structure of Zika virus NS5 reveals a conserved domain conformation
- (2017) Boxiao Wang et al. Nature Communications
- Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase
- (2017) Andre S. Godoy et al. Nature Communications
- Crystal structure of full-lengthZika virusNS5 protein reveals a conformation similar toJapanese encephalitis virusNS5
- (2017) Anup K. Upadhyay et al. Acta Crystallographica Section F-Structural Biology Communications
- Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor
- (2016) Delia Tarantino et al. ANTIVIRAL RESEARCH
- Zika virus: History, emergence, biology, and prospects for control
- (2016) Scott C. Weaver et al. ANTIVIRAL RESEARCH
- N6 -Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection
- (2016) Nandan S. Gokhale et al. Cell Host & Microbe
- Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses
- (2016) Laurent Chatel-Chaix et al. Cell Host & Microbe
- Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy
- (2016) Qiming Liang et al. Cell Stem Cell
- A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening
- (2016) Christian G. Noble et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design
- (2016) Fumiaki Yokokawa et al. JOURNAL OF MEDICINAL CHEMISTRY
- SUMO Modification Stabilizes Dengue Virus Nonstructural Protein 5 To Support Virus Replication
- (2016) Chan-I Su et al. JOURNAL OF VIROLOGY
- MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1
- (2016) Zheng Chen et al. JOURNAL OF VIROLOGY
- Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives
- (2016) Bruno Coutard et al. JOURNAL OF VIROLOGY
- The Many Faces of the Flavivirus NS5 Protein in Antagonism of Type I Interferon Signaling
- (2016) Sonja M. Best JOURNAL OF VIROLOGY
- Evasion of early innate immune response by 2′- O -methylation of dengue genomic RNA
- (2016) David C. Chang et al. VIROLOGY
- Flavivirus NS1: a multifaceted enigmatic viral protein
- (2016) Meghana Rastogi et al. Virology Journal
- Structures of NS5 Methyltransferase from Zika Virus
- (2016) Javier Coloma et al. Cell Reports
- The quest for host targets to combat dengue virus infections
- (2016) Eliana G Acosta et al. Current Opinion in Virology
- The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production
- (2016) Moon Y. F. Tay et al. PLoS Pathogens
- The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
- (2016) Federico A. De Maio et al. PLoS Pathogens
- Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
- (2016) Siew Pheng Lim et al. PLoS Pathogens
- Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface
- (2016) Valerie J. Klema et al. PLoS Pathogens
- Intrinsically Disordered Side of the Zika Virus Proteome
- (2016) Rajanish Giri et al. Frontiers in Cellular and Infection Microbiology
- The search for nucleoside/nucleotide analog inhibitors of dengue virus
- (2015) Yen-Liang Chen et al. ANTIVIRAL RESEARCH
- Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening
- (2015) Pornwaratt Niyomrattanakit et al. ANTIVIRAL RESEARCH
- The dengue virus NS5 protein as a target for drug discovery
- (2015) Siew Pheng Lim et al. ANTIVIRAL RESEARCH
- The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development
- (2015) Dahai Luo et al. ANTIVIRAL RESEARCH
- Secondary structure and membrane topology of dengue virus NS4B N-terminal 125 amino acids
- (2015) Yan Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression
- (2015) Kirk J. Lubick et al. Cell Host & Microbe
- Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication
- (2015) Yongqian Zhao et al. JOURNAL OF VIROLOGY
- Characterization of Dengue Virus NS4A and NS4B Protein Interaction
- (2015) Jing Zou et al. JOURNAL OF VIROLOGY
- Determinants of Dengue Virus NS4A Protein Oligomerization
- (2015) Chia Min Lee et al. JOURNAL OF VIROLOGY
- Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
- (2015) Yongqian Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for RNA replication by the hepatitis C virus polymerase
- (2015) T. C. Appleby et al. SCIENCE
- NF-κB is required for dengue virus NS5-induced RANTES expression
- (2015) Sasiprapa Khunchai et al. VIRUS RESEARCH
- Flaviviral Replication Complex: Coordination between RNA Synthesis and 5’-RNA Capping
- (2015) Valerie Klema et al. Viruses-Basel
- Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant
- (2015) Nadine A. Dalrymple et al. mBio
- Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2’-O-Methylation Mutant
- (2015) Bianca Schmid et al. PLoS Pathogens
- A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication
- (2015) Yongqian Zhao et al. PLoS Pathogens
- Structural insight and flexible features of NS5 proteins from all four serotypes of Dengue virus in solution
- (2015) Wuan Geok Saw et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase
- (2015) Matthew Brecher et al. PLoS One
- Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development
- (2014) Célia Caillet-Saguy et al. ANTIVIRAL RESEARCH
- The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral Replication
- (2014) Moon Y. F. Tay et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two Distinct Sets of NS2A Molecules Are Responsible for Dengue Virus RNA Synthesis and Virion Assembly
- (2014) Xuping Xie et al. JOURNAL OF VIROLOGY
- Perturbation in the Conserved Methyltransferase-Polymerase Interface of Flavivirus NS5 Differentially Affects Polymerase Initiation and Elongation
- (2014) Jiqin Wu et al. JOURNAL OF VIROLOGY
- The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain
- (2014) Supanee Potisopon et al. NUCLEIC ACIDS RESEARCH
- The Interface between Methyltransferase and Polymerase of NS5 Is Essential for Flavivirus Replication
- (2014) Xiao-Dan Li et al. PLoS Neglected Tropical Diseases
- Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin
- (2013) M.Y.F. Tay et al. ANTIVIRAL RESEARCH
- Ten years of dengue drug discovery: Progress and prospects
- (2013) Siew Pheng Lim et al. ANTIVIRAL RESEARCH
- A Novel Promising Therapeutic Option Against Hepatitis C Virus: An Oral Nucleotide NS5B Polymerase Inhibitor Sofosbuvir
- (2013) I. Gentile et al. CURRENT MEDICINAL CHEMISTRY
- A Crystal Structure of the Dengue Virus Non-structural Protein 5 (NS5) Polymerase Delineates Interdomain Amino Acid Residues That Enhance Its Thermostability andde NovoInitiation Activities
- (2013) Siew Pheng Lim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Localization of Dengue Virus Nonstructural Protein 5 Does Not Strictly Correlate with Efficient Viral RNA Replication and Inhibition of Type I Interferon Signaling
- (2013) A. Kumar et al. JOURNAL OF VIROLOGY
- Structures of Coxsackievirus, Rhinovirus, and Poliovirus Polymerase Elongation Complexes Solved by Engineering RNA Mediated Crystal Contacts
- (2013) Peng Gong et al. PLoS One
- Protein–protein interactions among West Nile non-structural proteins and transmembrane complex formation in mammalian cells
- (2013) Li Yu et al. VIROLOGY
- Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques
- (2013) Roland Züst et al. PLoS Pathogens
- Crystal Structure of the Full-Length Japanese Encephalitis Virus NS5 Reveals a Conserved Methyltransferase-Polymerase Interface
- (2013) Guoliang Lu et al. PLoS Pathogens
- Establishment of a robust dengue virus NS3–NS5 binding assay for identification of protein–protein interaction inhibitors
- (2012) Hirotaka Takahashi et al. ANTIVIRAL RESEARCH
- Interaction of dengue virus nonstructural protein 5 with Daxx modulates RANTES production
- (2012) Sasiprapa Khunchai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography
- (2012) Ritwika S. Basu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Innate Immunity Evasion by Dengue Virus
- (2012) Juliet Morrison et al. Viruses-Basel
- Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome
- (2012) Barbara Selisko et al. PLoS Pathogens
- Exploitation of cellular pathways by Dengue virus
- (2011) Wolfgang Fischl et al. CURRENT OPINION IN MICROBIOLOGY
- Full-length Dengue Virus RNA-dependent RNA Polymerase-RNA/DNA Complexes
- (2011) Michal R. Szymanski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The F1 Motif of Dengue Virus Polymerase NS5 Is Involved in Promoter-Dependent RNA Synthesis
- (2011) N. G. Iglesias et al. JOURNAL OF VIROLOGY
- Conventional and unconventional mechanisms for capping viral mRNA
- (2011) Etienne Decroly et al. NATURE REVIEWS MICROBIOLOGY
- Analysis of RNA Binding by the Dengue Virus NS5 RNA Capping Enzyme
- (2011) Brittney R. Henderson et al. PLoS One
- N-linked glycosylation of dengue virus NS1 protein modulates secretion, cell-surface expression, hexamer stability, and interactions with human complement
- (2011) Pawit Somnuke et al. VIROLOGY
- Inhibition of Dengue Virus by an Ester Prodrug of an Adenosine Analog
- (2010) Y.-L. Chen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus Methyltransferase
- (2010) Hongping Dong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RNA Sequences and Structures Required for the Recruitment and Activity of the Dengue Virus Polymerase
- (2010) Claudia V. Filomatori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase
- (2010) Siew Pheng Lim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel
- (2010) P. Niyomrattanakit et al. JOURNAL OF VIROLOGY
- 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
- (2010) Stephane Daffis et al. NATURE
- Biochemical and genetic characterization of dengue virus methyltransferase
- (2010) Hongping Dong et al. VIROLOGY
- N-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase
- (2009) Zheng Yin et al. JOURNAL OF MEDICINAL CHEMISTRY
- NS5 of Dengue Virus Mediates STAT2 Binding and Degradation
- (2009) J. Ashour et al. JOURNAL OF VIROLOGY
- Nucleic acid polymerases use a general acid for nucleotidyl transfer
- (2009) Christian Castro et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure
- (2009) M. Issur et al. RNA
- Flavivirus methyltransferase: A novel antiviral target
- (2008) Hongping Dong et al. ANTIVIRAL RESEARCH
- A scintillation proximity assay for dengue virus NS5 2′-O-methyltransferase—kinetic and inhibition analyses
- (2008) S LIM et al. ANTIVIRAL RESEARCH
- The flavivirus polymerase as a target for drug discovery
- (2008) Hélène Malet et al. ANTIVIRAL RESEARCH
- Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein
- (2008) Dahai Luo et al. EMBO JOURNAL
- Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
- (2008) Michela Bollati et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural and Functional Studies of the Promoter Element for Dengue Virus RNA Replication
- (2008) M. F. Lodeiro et al. JOURNAL OF VIROLOGY
- West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism
- (2008) H. Dong et al. JOURNAL OF VIROLOGY
- Genome cyclization as strategy for flavivirus RNA replication
- (2008) Sergio M. Villordo et al. VIRUS RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now