The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

Development of viable TAP-tagged dengue virus for investigation of host–virus interactions in viral replication

(2016) Teera Poyomtip et al.   JOURNAL OF GENERAL VIROLOGY

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

(2016) Stanley Chun-Wei Lee et al.   NATURE MEDICINE

The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing

(2015) Wenyu Lin et al.   JOURNAL OF HEPATOLOGY

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway

(2015) Chuanlong Zhu et al.   JOURNAL OF VIROLOGY

Zika virus: following the path of dengue and chikungunya?

(2015) Didier Musso et al.   LANCET

Functional Splicing Network Reveals Extensive Regulatory Potential of the Core Spliceosomal Machinery

(2015) Panagiotis Papasaikas et al.   MOLECULAR CELL

Acute Effects of Light on Alternative Splicing in Light-Grown Plants

(2015) Estefania Mancini et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses

(2015) Claire A. Schreiber et al.   PLoS Pathogens

The global landscape of intron retentions in lung adenocarcinoma

(2014) Qu Zhang et al.   BMC Medical Genomics

Widespread intron retention in mammals functionally tunes transcriptomes

(2014) Ulrich Braunschweig et al.   GENOME RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

High-Throughput Quantitative Proteomic Analysis of Dengue Virus Type 2 Infected A549 Cells

(2014) Han-Chen Chiu et al.   PLoS One

Cytoplasmic Viral RNA-Dependent RNA Polymerase Disrupts the Intracellular Splicing Machinery by Entering the Nucleus and Interfering with Prp8

(2014) Yen-Chin Liu et al.   PLoS Pathogens

Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin

(2013) M.Y.F. Tay et al.   ANTIVIRAL RESEARCH

Serotype-specific Differences in Dengue Virus Non-structural Protein 5 Nuclear Localization

(2013) Holger Hannemann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Localization of Dengue Virus Nonstructural Protein 5 Does Not Strictly Correlate with Efficient Viral RNA Replication and Inhibition of Type I Interferon Signaling

(2013) A. Kumar et al.   JOURNAL OF VIROLOGY

Elucidating Novel Hepatitis C Virus–Host Interactions Using Combined Mass Spectrometry and Functional Genomics Approaches

(2013) Marie-Anne Germain et al.   MOLECULAR & CELLULAR PROTEOMICS

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

Poliovirus 2A Protease Triggers a Selective Nucleo-Cytoplasmic Redistribution of Splicing Factors to Regulate Alternative Pre-mRNA Splicing

(2013) Enrique Álvarez et al.   PLoS One

Poliovirus infection induces the co-localization of cellular protein SRp20 with TIA-1, a cytoplasmic stress granule protein

(2013) Kerry D. Fitzgerald et al.   VIRUS RESEARCH

RNA sequencing of cancer reveals novel splicing alterations

(2013) Jeyanthy Eswaran et al.   Scientific Reports

Host Cell Transcriptome Profile during Wild-Type and Attenuated Dengue Virus Infection

(2013) October M. Sessions et al.   PLoS Neglected Tropical Diseases

Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

(2013) Juliet Morrison et al.   PLoS Pathogens

The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII 

(2012) A. L. Greninger et al.   JOURNAL OF VIROLOGY

Innate Immunity Evasion by Dengue Virus

(2012) Juliet Morrison et al.   Viruses-Basel

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion

(2012) Cyrille Girard et al.   Nature Communications

2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase

(2012) Hongping Dong et al.   PLoS Pathogens

Exploitation of cellular pathways by Dengue virus

(2011) Wolfgang Fischl et al.   CURRENT OPINION IN MICROBIOLOGY

Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

(2011) A. Corrionero et al.   GENES & DEVELOPMENT

A functional genomic screen reveals novel host genes that mediate interferon-alpha’s effects against hepatitis C virus

(2011) Hong Zhao et al.   JOURNAL OF HEPATOLOGY

Uncoupling cis-Acting RNA Elements from Coding Sequences Revealed a Requirement of the N-Terminal Region of Dengue Virus Capsid Protein in Virus Particle Formation

(2011) M. M. Samsa et al.   JOURNAL OF VIROLOGY

Identification of RNA Helicase A as a Cellular Factor That Interacts with Influenza A Virus NS1 Protein and Its Role in the Virus Life Cycle

(2011) L. Lin et al.   JOURNAL OF VIROLOGY

A Physical Interaction Network of Dengue Virus and Human Proteins

(2011) Sudip Khadka et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteomic Analysis of Virus-Host Interactions in an Infectious Context Using Recombinant Viruses

(2011) Anastassia V. Komarova et al.   MOLECULAR & CELLULAR PROTEOMICS

Novel splice variants of human IKKε negatively regulate IKKε-induced IRF3 and NF-kB activation

(2010) Anja Koop et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Herpes simplex virus-1 induces expression of a novel MxA isoform that enhances viral replication

(2010) Chia-Chi Ku et al.   IMMUNOLOGY AND CELL BIOLOGY

RNA Sequences and Structures Required for the Recruitment and Activity of the Dengue Virus Polymerase

(2010) Claudia V. Filomatori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purification and characterization of HIV–human protein complexes

(2010) Stefanie Jäger et al.   METHODS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Dengue Virus NS5 Inhibits Interferon‐α Signaling by Blocking Signal Transducer and Activator of Transcription 2 Phosphorylation

(2009) Michela Mazzon et al.   JOURNAL OF INFECTIOUS DISEASES

NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

(2009) J. Ashour et al.   JOURNAL OF VIROLOGY

Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

(2009) Marcelo M. Samsa et al.   PLoS Pathogens

Mutagenesis of the Dengue Virus Type 2 NS5 Methyltransferase Domain

(2008) Helga Kroschewski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling☆

(2008) Sonya P. Lad et al.   MOLECULAR IMMUNOLOGY