Systems biology analysis of longitudinal functional response of endothelial cells to shear stress

Spatial phenotyping of the endocardial endothelium as a function of intracardiac hemodynamic shear stress

(2017) Margaret E. McCormick et al.   JOURNAL OF BIOMECHANICS

Effects of shear stress on endothelial cells: go with the flow

(2016) D. A. Chistiakov et al.   Acta Physiologica

The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches

(2016) Rachel D. Simmons et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from PML-induced Senescence

(2016) M. Acevedo et al.   CANCER RESEARCH

miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal TransitionNovelty and Significance

(2016) Ming He et al.   CIRCULATION RESEARCH

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

(2016) Michael A. Gimbrone et al.   CIRCULATION RESEARCH

E2F1 transcription factor and its impact on growth factor and cytokine signaling

(2016) Mustafa Gokhan Ertosun et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CXCR4 signaling in health and disease

(2016) Tommaso Pozzobon et al.   IMMUNOLOGY LETTERS

Endothelial fluid shear stress sensing in vascular health and disease

(2016) Nicolas Baeyens et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies

(2016) Swastika Sur et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Deep transcriptomic profiling reveals the similarity between endothelial cells cultured under static and oscillatory shear stress conditions

(2016) Congzhen Qiao et al.   PHYSIOLOGICAL GENOMICS

Ion Channels in Endothelial Responses to Fluid Shear Stress

(2016) Kristin A. Gerhold et al.   PHYSIOLOGY

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

(2016) Solene M. Evrard et al.   Nature Communications

The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence

(2015) Monika Maleszewska et al.   ANGIOGENESIS

Modulation of p38 kinase by DUSP4 is important in regulating cardiovascular function under oxidative stress

(2015) Alma Barajas-Espinosa et al.   FREE RADICAL BIOLOGY AND MEDICINE

E2F1 Transcription Factor RegulatesO-linkedN-acetylglucosamine (O-GlcNAc) Transferase andO-GlcNAcase Expression

(2015) Senthilkumar Muthusamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis

(2015) Pierre-Damien Denechaud et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes

(2015) Wei Li et al.   Molecular Cancer

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The BioMart community portal: an innovative alternative to large, centralized data repositories

(2015) Damian Smedley et al.   NUCLEIC ACIDS RESEARCH

Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression

(2015) J Liu et al.   Cell Death & Disease

V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy

(2015) Nathalie Meo-Evoli et al.   Oncotarget

Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

(2014) Jing Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Proteome-Scale Map of the Human Interactome Network

(2014) Thomas Rolland et al.   CELL

Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1

(2014) Jing Zhou et al.   Cellular and Molecular Bioengineering

The Essential Autophagy GeneATG7Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition

(2014) Krishna K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression, Regulation and Function of Human Metallothioneins in Endothelial Cells

(2014) Iris A. Schulkens et al.   JOURNAL OF VASCULAR RESEARCH

Transcriptional regulation of graded Hedgehog signaling

(2014) Kristin N. Falkenstein et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Oxidative stress in angiogenesis and vascular disease

(2013) Y.-W. Kim et al.   BLOOD

Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

(2013) J. S. Jakobsen et al.   GENOME RESEARCH

PharmGKB summary

(2013) Ellen M. McDonagh et al.   Pharmacogenetics and Genomics

DRAM1 Regulates Autophagy Flux through Lysosomes

(2013) Xing-Ding Zhang et al.   PLoS One

OSA: a fast and accurate alignment tool for RNA-Seq

(2012) Jun Hu et al.   BIOINFORMATICS

Vascular endothelium, hemodynamics, and the pathobiology of atherosclerosis

(2012) Michael A. Gimbrone et al.   CARDIOVASCULAR PATHOLOGY

An integrated view of cyclin E function and regulation

(2012) Ka Tat Siu et al.   CELL CYCLE

ENCODE Data in the UCSC Genome Browser: year 5 update

(2012) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation

(2012) Laura Tornatore et al.   TRENDS IN CELL BIOLOGY

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

(2012) Shauna A Henley et al.   Cell Division

Adaptive response of vascular endothelial cells to an acute increase in shear stress magnitude

(2011) Ji Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

CXCL12 (SDF1 )-CXCR4/CXCR7 Pathway Inhibition: An Emerging Sensitizer for Anticancer Therapies?

(2011) D. G. Duda et al.   CLINICAL CANCER RESEARCH

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants

(2010) Krishna P. Bhabak et al.   ACCOUNTS OF CHEMICAL RESEARCH

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

(2010) Albena T. Dinkova-Kostova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

(2010) C.-W. Ni et al.   BLOOD

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression

(2010) T. Yamaguchi et al.   GENES & DEVELOPMENT

Discovery and characterization of chromatin states for systematic annotation of the human genome

(2010) Jason Ernst et al.   NATURE BIOTECHNOLOGY

ConsensusPathDB: toward a more complete picture of cell biology

(2010) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

Shear stress, SIRT1, and vascular homeostasis

(2010) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EKLF/KLF1 Controls Cell Cycle Entry via Direct Regulation of E2f2

(2009) Michael R. Tallack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

Regulation and function of JunB in cell proliferation

(2008) Marc Piechaczyk et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Transcriptional Regulation of Adipogenesis by KLF4

(2008) Kıvanç Birsoy et al.   Cell Metabolism

A comprehensive modular map of molecular interactions in RB/E2F pathway

(2008) Laurence Calzone et al.   Molecular Systems Biology