The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence
Authors
Keywords
Endothelial cell, Enhancer of zeste homolog-2 (EZH2), Fluid shear stress (FSS), Mechanotransduction, Chromatin
Journal
ANGIOGENESIS
Volume 19, Issue 1, Pages 9-24
Publisher
Springer Nature
Online
2015-09-29
DOI
10.1007/s10456-015-9485-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis
- (2015) Oncotarget
- YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK
- (2014) Ling-Chu Chang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Hemodynamic Disturbed Flow Induces Differential DNA Methylation of Endothelial Kruppel-Like Factor 4 Promoter In Vitro and In Vivo
- (2014) Yi-Zhou Jiang et al. CIRCULATION RESEARCH
- Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
- (2014) Jessilyn Dunn et al. JOURNAL OF CLINICAL INVESTIGATION
- Enhancer of zeste homolog 2 is widely expressed in T-cell neoplasms, is associated with high proliferation rate and correlates with MYC and pSTAT3 expression in a subset of cases
- (2014) Min Shi et al. LEUKEMIA & LYMPHOMA
- Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide
- (2014) Eva Madi Riising et al. MOLECULAR CELL
- Amygdalin Blocks Bladder Cancer Cell Growth In Vitro by Diminishing Cyclin A and cdk2
- (2014) Jasmina Makarević et al. PLoS One
- EZH2 Is Associated with Malignant Behavior in Pancreatic IPMN via p27Kip1 Downregulation
- (2014) Hideyuki Kuroki et al. PLoS One
- Enhancer of Zeste Homolog 2 (EZH2) Promotes Progression of Cholangiocarcinoma Cells by Regulating Cell Cycle and Apoptosis
- (2013) Shigeki Nakagawa et al. ANNALS OF SURGICAL ONCOLOGY
- Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells
- (2013) Evan S Bardot et al. EMBO JOURNAL
- Mechanosensitive microRNAs—role in endothelial responses to shear stress and redox state
- (2013) Traci Marin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mechanical regulation of epigenetics in vascular biology and pathobiology
- (2013) Li-Jing Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Large-scale gene function analysis with the PANTHER classification system
- (2013) Huaiyu Mi et al. Nature Protocols
- Ensembl 2014
- (2013) Paul Flicek et al. NUCLEIC ACIDS RESEARCH
- Epigenetic Regulation of Cell Adhesion and Communication by Enhancer of Zeste Homolog 2 in Human Endothelial Cells
- (2012) Henryk Dreger et al. HYPERTENSION
- IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner
- (2012) Monika Maleszewska et al. IMMUNOBIOLOGY
- Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes
- (2012) Sadie C. Slater et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells
- (2012) Junko Kikuchi et al. LUNG CANCER
- Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
- (2012) Cole Trapnell et al. Nature Protocols
- STRING v9.1: protein-protein interaction networks, with increased coverage and integration
- (2012) Andrea Franceschini et al. NUCLEIC ACIDS RESEARCH
- Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow
- (2012) D.-Y. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML
- (2011) J. Zhou et al. BLOOD
- Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
- (2011) Jeng-Jiann Chiu et al. PHYSIOLOGICAL REVIEWS
- Down-Regulation of miR-101 in Endothelial Cells Promotes Blood Vessel Formation through Reduced Repression of EZH2
- (2011) Michiel Smits et al. PLoS One
- REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms
- (2011) Fran Supek et al. PLoS One
- Ensembl BioMarts: a hub for data retrieval across taxonomic space
- (2011) R. J. Kinsella et al. Database-The Journal of Biological Databases and Curation
- Regulation of Tumor Angiogenesis by EZH2
- (2010) Chunhua Lu et al. CANCER CELL
- Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Krüppel-like Factor 4 (KLF4)
- (2010) Nils Ohnesorge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells
- (2010) PAUL R. CLARK et al. MICROCIRCULATION
- The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events
- (2010) Delquin Gong et al. MOLECULAR BIOLOGY OF THE CELL
- CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells
- (2010) Yongkun Wei et al. NATURE CELL BIOLOGY
- Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2
- (2010) Shuai Chen et al. NATURE CELL BIOLOGY
- Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
- (2010) Jeremy Goecks et al. GENOME BIOLOGY
- Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells
- (2009) Guadalupe Villarreal et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The value of EZH2, p27kip1, BMI-1 and MIB-1 on biopsy specimens with low-risk prostate cancer in selecting men with significant prostate cancer at prostatectomy
- (2009) Tineke Wolters et al. BJU INTERNATIONAL
- BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams
- (2008) Tim Hulsen et al. BMC GENOMICS
- Mechanotransduction in vascular physiology and atherogenesis
- (2008) Cornelia Hahn et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- STRING 8--a global view on proteins and their functional interactions in 630 organisms
- (2008) L. J. Jensen et al. NUCLEIC ACIDS RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started