Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies

Inhibition of CDC25B Phosphatase Through Disruption of Protein–Protein Interaction

(2014) George Lund et al.   ACS Chemical Biology

Discovery and characterization of novel imidazopyridine derivative CHEQ-2 as a potent CDC25 inhibitor and promising anticancer drug candidate

(2014) Yu'ning Song et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms

(2014) Annette Brenner et al.   MOLECULES

A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death

(2013) Emilie Bana et al.   MOLECULAR CARCINOGENESIS

Development of a matrix-assisted laser desorption/ionization–mass spectrometry screening test to evidence reversible and irreversible inhibitors of CDC25 phosphatases

(2012) E. Sibille et al.   ANALYTICAL BIOCHEMISTRY

Cell Cycle Control by the CDC25 Phosphatases

(2012) Bernadette Aressy et al.   Anti-Cancer Agents in Medicinal Chemistry

The Role of Cdc25A in the Regulation of Cell Proliferation and Apoptosis

(2012) Tao Shen et al.   Anti-Cancer Agents in Medicinal Chemistry

Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?

(2012) Hidemasa Goto et al.   CANCER SCIENCE

Discovery of New Inhibitors of Cdc25B Dual Specificity Phosphatases by Structure-Based Virtual Screening

(2012) Antonio Lavecchia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase

(2011) Valérie Lobjois et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation

(2011) Shunfu Piao et al.   CELL CYCLE

Ser149Is Another Potential PKA Phosphorylation Target of Cdc25B in G2/M Transition of Fertilized Mouse Eggs

(2011) Jianying Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cdc14B Promotes Progression through Mitosis by Dephosphorylating Cdc25 and Regulating Cdk1/Cyclin B Activity

(2011) Indra Tumurbaatar et al.   PLoS One

Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes

(2010) Zhihui Wang et al.   BMC CANCER

Inhibition of androgen receptor and Cdc25A phosphatase as a combination targeted therapy in molecular apocrine breast cancer

(2010) Ali Naderi et al.   CANCER LETTERS

Protein kinase A regulates resumption of meiosis by phosphorylation of Cdc25B in mammalian oocytes

(2010) Giorgia Pirino et al.   CELL CYCLE

Mitotic Phosphorylation of Cdc25B Ser321Disrupts 14-3-3 Binding to the High Affinity Ser323Site

(2010) Puji Astuti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cdc14A Phosphatase Modulates the G2/M Transition through Cdc25A and Cdc25B

(2010) María D. Vázquez-Novelle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK-mediated Phosphorylation of Cdc25C Regulates Cell Cycle Entry and G2/M DNA Damage Checkpoint

(2010) Gustavo J. Gutierrez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Reconstitution of Mitotic CDK1 Activation in Somatic Cell Extracts

(2010) Richard W. Deibler et al.   MOLECULAR CELL

Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction

(2010) Y Honaker et al.   ONCOGENE

Distinct Pools of cdc25C Are Phosphorylated on Specific TP Sites and Differentially Localized in Human Mitotic Cells

(2010) Celine Franckhauser et al.   PLoS One

G2/M accumulation in prostate cancer cell line PC-3 is induced by Cdc25 inhibitor 7-chloro-6-(2-morpholin-4-ylethylamino) quinoline-5, 8-dione (DA 3003-2)

(2010) KAORU NEMOTO   Experimental and Therapeutic Medicine

LGH00031, a novel ortho-quinonoid inhibitor of cell division cycle 25B, inhibits human cancer cells via ROS generation

(2009) Yu-bo Zhou et al.   ACTA PHARMACOLOGICA SINICA

The polo-like kinase 1 regulates CDC25B-dependent mitosis entry

(2009) Valerie Lobjois et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Stress-Activated Mitogen-Activated Protein Kinases c-Jun NH2-Terminal Kinase and p38 Target Cdc25B for Degradation

(2009) S. Uchida et al.   CANCER RESEARCH

MAPK Pathway Activation Delays G2/M Progression by Destabilizing Cdc25B

(2009) Puji Astuti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Extracellular Signal-regulated Kinase–Mitogen-activated Protein Kinase Pathway Phosphorylates and Targets Cdc25A for SCFβ-TrCP-dependent Degradation for Cell Cycle Arrest

(2009) Michitaka Isoda et al.   MOLECULAR BIOLOGY OF THE CELL

Differential phosphorylation of Cdc25C phosphatase in mitosis

(2008) Jérôme Bonnet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CDC25B Acts as a Potential Target of PRKACA in Fertilized Mouse Eggs1

(2008) Cheng Cui et al.   BIOLOGY OF REPRODUCTION

CDC25A Phosphatase: a Rate-Limiting Oncogene That Determines Genomic Stability

(2008) D. Ray et al.   CANCER RESEARCH

The cell cycle control protein cdc25C is present, and phosphorylated on serine 214 in the transition from germinal vesicle to metaphase II in human oocyte meiosis

(2007) S. Cunat et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT