An integrated view of cyclin E function and regulation

Mcl-1 Ubiquitination and Destruction

(2015) Hiroyuki Inuzuka et al.   Oncotarget

Impact of cyclin E overexpression on Smad3 activity in breast cancer cell lines 

(2011) Anne Cooley et al.   CELL CYCLE

miR-27a regulation of SCFFbw7in cell division control and cancer

(2011) Charles Spruck   CELL CYCLE

Centrosomal localization of cyclins E and A

(2011) Gaetan Pascreau et al.   CELL CYCLE

MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression

(2011) Mikael Lerner et al.   CELL CYCLE

Hypoxia-Inducible Factor 1 Is Activated by Dysregulated Cyclin E during Mammary Epithelial Morphogenesis

(2011) T. Sengupta et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

(2011) Mardo Kõivomägi et al.   MOLECULAR CELL

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

(2011) Konstantinos J Mavrakis et al.   NATURE GENETICS

Cyclins A and E trigger DNA damage

(2010) Junko Odajima et al.   CELL CYCLE

Activation of Cdk2/Cyclin E complexes is dependent on the origin of replication licensing factor Cdc6 in mammalian cells

(2010) Cara L. Lunn et al.   CELL CYCLE

The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis

(2010) Kuppusamy Balamurugan et al.   EMBO JOURNAL

MicroRNA-223 Regulates Cyclin E Activity by Modulating Expression of F-box and WD-40 Domain Protein 7

(2010) Yanfei Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo

(2010) Laura A. Buttitta et al.   JOURNAL OF CELL BIOLOGY

The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells

(2010) Uta Kossatz et al.   JOURNAL OF CLINICAL INVESTIGATION

Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2

(2010) Shuai Chen et al.   NATURE CELL BIOLOGY

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

(2009) J. A. Pulikkan et al.   BLOOD

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

(2009) M. E. Figueroa et al.   BLOOD

Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis

(2009) Vera V. Grinkevich et al.   CANCER CELL

Phosphorylation of Mcm2 by Cdc7 Promotes Pre-replication Complex Assembly during Cell-Cycle Re-entry

(2009) Li-Chiou Chuang et al.   MOLECULAR CELL

Cdk2 suppresses cellular senescence induced by the c-myc oncogene

(2009) Stefano Campaner et al.   NATURE CELL BIOLOGY

Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

(2009) A Satyanarayana et al.   ONCOGENE

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

(2009) P. Hydbring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Feed-Forward Loop Involving Protein Kinase C  and MicroRNAs Regulates Tumor Cell Cycle

(2008) E. E.W. Cohen et al.   CANCER RESEARCH

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo

(2008) A. C. Minella et al.   GENES & DEVELOPMENT

SCFCdc4 acts antagonistically to the PGC-1  transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis

(2008) B. L. Olson et al.   GENES & DEVELOPMENT

Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase

(2008) Jonathan E. Grim et al.   JOURNAL OF CELL BIOLOGY

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates

(2008) J. D. Blethrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of CDK2 substrates in human cell lysates

(2008) Yong Chi et al.   GENOME BIOLOGY