Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo

(2013) Peter F. Davies et al.   CARDIOVASCULAR RESEARCH

Sterol Regulatory Element Binding Protein 2 Activation of NLRP3 Inflammasome in Endothelium Mediates Hemodynamic-Induced Atherosclerosis Susceptibility

(2013) Han Xiao et al.   CIRCULATION

Regulation of Vascular Smooth Muscle Cell Turnover by Endothelial Cell–Secreted MicroRNA-126

(2013) Jing Zhou et al.   CIRCULATION RESEARCH

BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow

(2013) J. Zhou et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

AMPK 2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6

(2013) B. Gongol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear stress activation of nuclear receptor PXR in endothelial detoxification

(2013) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis

(2013) Dong Ju Son et al.   Nature Communications

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

(2012) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

(2012) D.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of an Endothelial–Smooth Muscle Cell Coculture Model Using Phenotype-Controlled Smooth Muscle Cells

(2011) Naoya Sakamoto et al.   ANNALS OF BIOMEDICAL ENGINEERING

Flow-Dependent Regulation of Krüppel-Like Factor 2 Is Mediated by MicroRNA-92a

(2011) Wei Wu et al.   CIRCULATION

Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress–specific manner

(2011) Kel Vin Woo et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Disturbed flow in radial-cephalic arteriovenous fistulae for haemodialysis: low and oscillating shear stress locates the sites of stenosis

(2011) B. Ene-Iordache et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

PDGF-BB and TGF-β1 on cross-talk between endothelial and smooth muscle cells in vascular remodeling induced by low shear stress

(2011) Ying-Xin Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-Atherogenic Effect of Laminar Shear Stress via Nrf2 Activation

(2010) Wakako Takabe et al.   ANTIOXIDANTS & REDOX SIGNALING

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

(2010) C.-W. Ni et al.   BLOOD

MCP-1 Contributes to Arteriovenous Fistula Failure

(2010) J. P. Juncos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteomic Analysis of Shear Stress-Mediated Protection from TNF-α in Endothelial Cells

(2010) Julie K. Freed et al.   MICROCIRCULATION

Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth

(2010) K.-C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear stress, SIRT1, and vascular homeostasis

(2010) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells

(2010) X. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

(2010) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis

(2009) Douglas Nam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Molecular Mechanisms Responsible for the Atheroprotective Effects of Laminar Shear Stress

(2009) Shi Pan   ANTIOXIDANTS & REDOX SIGNALING

Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression

(2009) Angela Young et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

(2009) W. Wang et al.   BLOOD

Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow

(2009) Anna Zampetaki et al.   CIRCULATION

Shear Stress Induces Synthetic-to-Contractile Phenotypic Modulation in Smooth Muscle Cells via Peroxisome Proliferator-Activated Receptor α/δ Activations by Prostacyclin Released by Sheared Endothelial Cells

(2009) Min-Chien Tsai et al.   CIRCULATION RESEARCH

The Subendothelial Extracellular Matrix Modulates JNK Activation by Flow

(2009) Cornelia Hahn et al.   CIRCULATION RESEARCH

Chronic Endoplasmic Reticulum Stress Activates Unfolded Protein Response in Arterial Endothelium in Regions of Susceptibility to Atherosclerosis

(2009) Mete Civelek et al.   CIRCULATION RESEARCH

Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow

(2009) L. Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GRP78 Upregulation by Atheroprone Shear Stress Via p38-, α2β1-Dependent Mechanism in Endothelial Cells

(2008) Ryan E. Feaver et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of Endothelial Nitric Oxide Synthase Activity by Proline-Rich Tyrosine Kinase 2 in Response to Fluid Shear Stress and Insulin

(2008) Beate Fisslthaler et al.   CIRCULATION RESEARCH

Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation

(2008) Yunhao Liu et al.   JOURNAL OF CELL BIOLOGY

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

(2008) Adam E. Mullick et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine