Effects of shear stress on endothelial cells: go with the flow

Endothelial PECAM-1 and its function in vascular physiology and atherogenic pathology

(2016) Dimitry A. Chistiakov et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

The role of miR-126 in embryonic angiogenesis, adult vascular homeostasis, and vascular repair and its alterations in atherosclerotic disease

(2016) Dimitry A. Chistiakov et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Vascular smooth muscle cell in atherosclerosis

(2015) D. A. Chistiakov et al.   Acta Physiologica

Association of aortic stiffness and wave reflections with coronary flow reserve in women without obstructive coronary artery disease: An ancillary study from the National Heart, Lung, and Blood Institute–sponsored Women’s Ischemia Syndrome Evaluation (WISE)

(2015) Wilmer W. Nichols et al.   AMERICAN HEART JOURNAL

Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells

(2015) Sara Baratchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA Mediation of Endothelial Inflammatory Response to Smooth Muscle Cells and Its Inhibition by Atheroprotective Shear StressNovelty and Significance

(2015) Li-Jing Chen et al.   CIRCULATION RESEARCH

Lower Extremity Manifestations of Peripheral Artery Disease: The Pathophysiologic and Functional Implications of Leg Ischemia

(2015) M. M. McDermott   CIRCULATION RESEARCH

Evidence for functional and dynamic microcompartmentation of Cav-1/TRPV4/KCa in caveolae of endothelial cells

(2015) Sybelle Goedicke-Fritz et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Rab7a and Rab27b control secretion of endothelial microRNA through extracellular vesicles

(2015) Nicolas Jaé et al.   FEBS LETTERS

Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex

(2015) Brian G. Coon et al.   JOURNAL OF CELL BIOLOGY

Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function

(2015) Kyung-Sun Heo et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular Endothelium: Functioning in Norm, Changes in Atherosclerosis and Current Dietary Approaches to Improve Endothelial Function

(2015) Dimitry Chistiakov et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

miRNAs in atherosclerotic plaque initiation, progression, and rupture

(2015) Ioannis Andreou et al.   TRENDS IN MOLECULAR MEDICINE

Markers of arterial stiffness in peripheral arterial disease

(2015) Marc Husmann et al.   Vasa-European Journal of Vascular Medicine

Endothelial Barrier and Its Abnormalities in Cardiovascular Disease

(2015) Dimitry A. Chistiakov et al.   Frontiers in Physiology

Autophagy Regulates Vascular Endothelial Cell eNOS and ET-1 Expression Induced by Laminar Shear Stress in an Ex Vivo Perfused System

(2014) Fengxia Guo et al.   ANNALS OF BIOMEDICAL ENGINEERING

Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

(2014) Jing Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanoresponsive Networks Controlling Vascular Inflammation

(2014) Matthew T. Bryan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prevention of Abdominal Aortic Aneurysm by Anti-MicroRNA-712 or Anti-MicroRNA-205 in Angiotensin II-Infused Mice

(2014) C. W. Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Flow-Sensitive microRNAs in Endothelial Dysfunction and Atherosclerosis

(2014) Sandeep Kumar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Early origins of adult disease: Low birth weight and vascular remodeling

(2014) Silvia Visentin et al.   ATHEROSCLEROSIS

Histone deacetylase 5 interacts with Krüppel-like factor 2 and inhibits its transcriptional activity in endothelium

(2014) Il-Sun Kwon et al.   CARDIOVASCULAR RESEARCH

Fluid Mechanical Forces and Endothelial Mitochondria: A Bioengineering Perspective

(2014) Christopher G. Scheitlin et al.   Cellular and Molecular Bioengineering

Thioredoxin-Interacting Protein Is a Biomechanical Regulator of Src Activity

(2014) Oded N. Spindel et al.   CIRCULATION RESEARCH

MiR-92a

(2014) Menno P.J. de Winther et al.   CIRCULATION RESEARCH

TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel

(2014) Juan Du et al.   FASEB JOURNAL

Loss of Syndecan-1 Induces a Pro-inflammatory Phenotype in Endothelial Cells with a Dysregulated Response to Atheroprotective Flow

(2014) Peter L. Voyvodic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unspliced X-box-binding Protein 1 (XBP1) Protects Endothelial Cells from Oxidative Stress through Interaction with Histone Deacetylase 3

(2014) Daniel Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shear Stress and Atherosclerosis

(2014) Kyung-Sun Heo et al.   MOLECULES AND CELLS

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

(2014) Andreas Schober et al.   NATURE MEDICINE

Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease

(2014) M. Reinhard et al.   NEUROLOGY

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PECAM-1 and caveolae form the mechanosensing complex necessary for NOX2 activation and angiogenic signaling with stopped flow in pulmonary endothelium

(2013) John Noel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Endothelial Insulin-Like Growth Factor-1 Modulates Proliferation and Phenotype of Smooth Muscle Cells Induced by Low Shear Stress

(2013) Lu Wang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mechanotransduction in the Endothelium: Role of Membrane Proteins and Reactive Oxygen Species in Sensing, Transduction, and Transmission of the Signal with Altered Blood Flow

(2013) Shampa Chatterjee et al.   ANTIOXIDANTS & REDOX SIGNALING

The Role of Platelet-Endothelial Cell Adhesion Molecule-1 in Atheroma Formation Varies Depending on the Site-Specific Hemodynamic Environment

(2013) Matthew Harrison et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo

(2013) Peter F. Davies et al.   CARDIOVASCULAR RESEARCH

MicroRNAs in flow-dependent vascular remodelling

(2013) Peter Neth et al.   CARDIOVASCULAR RESEARCH

MicroRNA-663 Regulates Human Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Neointimal Formation

(2013) Pan Li et al.   CIRCULATION RESEARCH

De-SUMOylation Enzyme of Sentrin/SUMO-Specific Protease 2 Regulates Disturbed Flow–Induced SUMOylation of ERK5 and p53 that Leads to Endothelial Dysfunction and Atherosclerosis

(2013) Kyung-Sun Heo et al.   CIRCULATION RESEARCH

Regulation of Vascular Smooth Muscle Cell Turnover by Endothelial Cell–Secreted MicroRNA-126

(2013) Jing Zhou et al.   CIRCULATION RESEARCH

Inhibition of MicroRNA-92a Prevents Endothelial Dysfunction and Atherosclerosis in Mice

(2013) Xavier Loyer et al.   CIRCULATION RESEARCH

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress

(2013) Yunhao Liu et al.   JOURNAL OF CELL BIOLOGY

Biomechanical regulation of vascular smooth muscle cell functions: from in vitro to in vivo understanding

(2013) J. Qiu et al.   Journal of the Royal Society Interface

Prostacyclin and PPARα Agonists Control Vascular Smooth Muscle Cell Apoptosis and Phenotypic Switch through Distinct 14-3-3 Isoforms

(2013) Yen-Chung Chen et al.   PLoS One

High Glucose Attenuates Shear-Induced Changes in Endothelial Hydraulic Conductivity by Degrading the Glycocalyx

(2013) Sandra V. Lopez-Quintero et al.   PLoS One

Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells

(2013) Ryan E. Feaver et al.   Nature Communications

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis

(2013) Dong Ju Son et al.   Nature Communications

Flow mechanotransduction regulates traction forces, intercellular forces, and adherens junctions

(2012) Lucas H. Ting et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Site-Specific MicroRNA-92a Regulation of Krüppel-Like Factors 4 and 2 in Atherosusceptible Endothelium

(2012) Yun Fang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids

(2012) Taras Afonyushkin et al.   ATHEROSCLEROSIS

Inhibition of miR-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury

(2012) Claudio Iaconetti et al.   BASIC RESEARCH IN CARDIOLOGY

Laminar shear stress enhances endothelial cell survival through a NADPH oxidase 2-dependent mechanism

(2012) Hyeona Jeon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE−/− mice

(2012) Gillian Douglas et al.   CARDIOVASCULAR RESEARCH

Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions

(2012) J. J. Wentzel et al.   CARDIOVASCULAR RESEARCH

Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation

(2012) Lin Li et al.   CELLULAR SIGNALLING

Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

(2012) Xiucui Ma et al.   CIRCULATION

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

Thioredoxin Interacting Protein Promotes Endothelial Cell Inflammation in Response to Disturbed Flow by Increasing Leukocyte Adhesion and Repressing Kruppel-Like Factor 2

(2012) Xiao-Qun Wang et al.   CIRCULATION RESEARCH

TRPV4 and the Regulation of Vascular Tone

(2012) Jessica A. Filosa et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages

(2012) Maliheh Nazari-Jahantigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Partial ligation-induced carotid artery occlusion induces leukocyte recruitment and lipid accumulation—A shear stress model of atherosclerosis

(2012) Hilda Merino et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow

(2012) Arif Yurdagul et al.   MOLECULAR BIOLOGY OF THE CELL

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Involvement of large conductance Ca2+-activated K+ channel in laminar shear stress-induced inhibition of vascular smooth muscle cell proliferation

(2012) Xiaoling Jia et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

(2012) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

(2012) D.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells

(2011) Chih-Wen Ni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS

(2011) Shampa Chatterjee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endothelial dysfunction as a cellular mechanism for vascular failure

(2011) Tetsuaki Hirase et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Development of an Endothelial–Smooth Muscle Cell Coculture Model Using Phenotype-Controlled Smooth Muscle Cells

(2011) Naoya Sakamoto et al.   ANNALS OF BIOMEDICAL ENGINEERING

Fluid Flow Mechanotransduction in Vascular Smooth Muscle Cells and Fibroblasts

(2011) Zhong-Dong Shi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Hemodynamic Activation of β-Catenin and T-Cell-Specific Transcription Factor Signaling in Vascular Endothelium Regulates Fibronectin Expression

(2011) Bradley D. Gelfand et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanotransduction of Flow-Induced Shear Stress by Endothelial Glycocalyx Fibers is Torque Determined

(2011) Xiao Liu et al.   ASAIO JOURNAL

Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells

(2011) Claudia Goettsch et al.   BASIC RESEARCH IN CARDIOLOGY

Loss of Methyl-CpG–Binding Domain Protein 2 Enhances Endothelial Angiogenesis and Protects Mice Against Hind-Limb Ischemic Injury

(2011) Xiaoquan Rao et al.   CIRCULATION

Flow-Dependent Regulation of Krüppel-Like Factor 2 Is Mediated by MicroRNA-92a

(2011) Wei Wu et al.   CIRCULATION

Coronary Artery Wall Shear Stress Is Associated With Progression and Transformation of Atherosclerotic Plaque and Arterial Remodeling in Patients With Coronary Artery Disease

(2011) Habib Samady et al.   CIRCULATION

Disturbed-Flow-Mediated Vascular Reactive Oxygen Species Induce Endothelial Dysfunction

(2011) Kyung-Sun Heo et al.   CIRCULATION JOURNAL

Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the Nox4 promoter

(2011) Srikanth Pendyala et al.   FREE RADICAL BIOLOGY AND MEDICINE

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

(2011) Kyung-Sun Heo et al.   JOURNAL OF CELL BIOLOGY

Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress

(2011) Stephen J. White et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Occludin: One Protein, Many Forms

(2011) P. M. Cummins   MOLECULAR AND CELLULAR BIOLOGY

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PDGF-BB and TGF-β1 on cross-talk between endothelial and smooth muscle cells in vascular remodeling induced by low shear stress

(2011) Ying-Xin Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High shear stress induces a strain increase in human coronary plaques over a 6-month period

(2011) Frank J.H. Gijsen et al.   EuroIntervention

Regulation of blood flow in the microcirculation: role of conducted vasodilation

(2010) P. Bagher et al.   Acta Physiologica

Anti-Atherogenic Effect of Laminar Shear Stress via Nrf2 Activation

(2010) Wakako Takabe et al.   ANTIOXIDANTS & REDOX SIGNALING

PKC  decreases eNOS protein stability via inhibitory phosphorylation of ERK5

(2010) P. Nigro et al.   BLOOD

Atheroprone Hemodynamics Regulate Fibronectin Deposition to Create Positive Feedback That Sustains Endothelial Inflammation

(2010) Ryan E. Feaver et al.   CIRCULATION RESEARCH

The switchable integrin adhesome

(2010) R. Zaidel-Bar et al.   JOURNAL OF CELL SCIENCE

MCP-1 Contributes to Arteriovenous Fistula Failure

(2010) J. P. Juncos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Responses of Endothelial Cells from Different Vessels to Inflammatory Cytokines and Shear Stress: Evidence for the Pliability of Endothelial Phenotype

(2010) N. Thin Luu et al.   JOURNAL OF VASCULAR RESEARCH

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Shear Stress Modulation of Smooth Muscle Cell Marker Genes in 2-D and 3-D Depends on Mechanotransduction by Heparan Sulfate Proteoglycans and ERK1/2

(2010) Zhong-Dong Shi et al.   PLoS One

Shear stress, SIRT1, and vascular homeostasis

(2010) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells

(2010) W. J. Rhee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

(2010) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

Focal adhesion kinase modulates activation of NF-κB by flow in endothelial cells

(2009) Tobias Petzold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis

(2009) Douglas Nam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Long-Term Cyclic Strain Downregulates Endothelial Nox4

(2009) Claudia Goettsch et al.   ANTIOXIDANTS & REDOX SIGNALING

Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression

(2009) Angela Young et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

(2009) Mustafa Zakkar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells

(2009) Claudia Goettsch et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

(2009) W. Wang et al.   BLOOD

Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow

(2009) Anna Zampetaki et al.   CIRCULATION

Shear Stress Induces Synthetic-to-Contractile Phenotypic Modulation in Smooth Muscle Cells via Peroxisome Proliferator-Activated Receptor α/δ Activations by Prostacyclin Released by Sheared Endothelial Cells

(2009) Min-Chien Tsai et al.   CIRCULATION RESEARCH

Activation and Signaling by the AMP-Activated Protein Kinase in Endothelial Cells

(2009) Beate Fisslthaler et al.   CIRCULATION RESEARCH

The Subendothelial Extracellular Matrix Modulates JNK Activation by Flow

(2009) Cornelia Hahn et al.   CIRCULATION RESEARCH

AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633

(2009) Zhen Chen et al.   CIRCULATION RESEARCH

Induction of the Cytoprotective Enzyme Heme Oxygenase-1 by Statins Is Enhanced in Vascular Endothelium Exposed to Laminar Shear Stress and Impaired by Disturbed Flow

(2009) Faisal Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atherosclerotic Plaque Surface Morphology in the Carotid Bifurcation Assessed With Multidetector Computed Tomography Angiography

(2009) Thomas T. de Weert et al.   STROKE

Strain distribution over plaques in human coronary arteries relates to shear stress

(2008) Frank J. H. Gijsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns

(2008) James A. Thomas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vascular endothelial responses to altered shear stress: Pathologic implications for atherosclerosis

(2008) Jeng-Jiann Chiu et al.   ANNALS OF MEDICINE

Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor–Deficient Mice

(2008) Reema Goel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial Cell PECAM-1 Promotes Atherosclerotic Lesions in Areas of Disturbed Flow in ApoE-Deficient Mice

(2008) Brian L. Harry et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells

(2008) Joost O. Fledderus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress

(2008) Tatyana Milovanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lung Ischemia: A Model for Endothelial Mechanotransduction

(2008) Shampa Chatterjee et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Inhibition of Endothelial Nitric Oxide Synthase Activity by Proline-Rich Tyrosine Kinase 2 in Response to Fluid Shear Stress and Insulin

(2008) Beate Fisslthaler et al.   CIRCULATION RESEARCH

Extracellular Signal-Regulated Kinase 5 SUMOylation Antagonizes Shear Stress–Induced Antiinflammatory Response and Endothelial Nitric Oxide Synthase Expression in Endothelial Cells

(2008) Chang-Hoon Woo et al.   CIRCULATION RESEARCH

Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis

(2008) Mustafa Zakkar et al.   CIRCULATION RESEARCH

Activation of p300 Histone Acetyltransferase Activity Is an Early Endothelial Response to Laminar Shear Stress and Is Essential for Stimulation of Endothelial Nitric-oxide Synthase mRNA Transcription

(2008) Wei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KLF2-dependent, Shear Stress-induced Expression of CD59

(2008) Anne R. Kinderlerer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation

(2008) Yunhao Liu et al.   JOURNAL OF CELL BIOLOGY

Inflammatory responses of endothelial cells experiencing reduction in flow after conditioning by shear stress

(2008) Nick M. Matharu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Localized Elevation of Shear Stress Is Related to Coronary Plaque Rupture

(2008) Yusaku Fukumoto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effects of cyclic strain on endothelial cell apoptosis and tubulogenesis are dependent on ROS production via NAD(P)H subunit p22phox

(2008) Baijun Kou et al.   MICROVASCULAR RESEARCH

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine

Nitric Oxide Modulates Chromatin Folding in Human Endothelial Cells via Protein Phosphatase 2A Activation and Class II Histone Deacetylases Nuclear Shuttling

(2007) Barbara Illi et al.   CIRCULATION RESEARCH