Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation
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Title
Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation
Authors
Keywords
Radiotherapy, Epithelial-mesenchymal transition, Metastasis, Cancer stem cells, Oncogenic metabolism, Tumour microenvironment, Reactive oxygen species, Radioresistance, Snail
Journal
Molecular Cancer
Volume 16, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-01-13
DOI
10.1186/s12943-016-0577-4
References
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Note: Only part of the references are listed.- LDH-A promotes malignant progression via activation of epithelial-to-mesenchymal transition and conferring stemness in muscle-invasive bladder cancer
- (2016) Fujin Jiang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines
- (2016) Daniel R. Sappington et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Surgery and radiation therapy of triple-negative breast cancers: From biology to clinics
- (2016) Jacques Bernier et al. BREAST
- Hallmarks of cancer stem cell metabolism
- (2016) Patricia Sancho et al. BRITISH JOURNAL OF CANCER
- Risk of second cancers in the era of modern radiation therapy: does the risk/benefit analysis overcome theoretical models?
- (2016) Cyrus Chargari et al. CANCER AND METASTASIS REVIEWS
- Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation
- (2016) Fei Zhao et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
- (2016) Philippe Gascard et al. GENES & DEVELOPMENT
- Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells
- (2016) Georgia-Persephoni Voulgaridou et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis
- (2016) Sonam Dhamija et al. INTERNATIONAL JOURNAL OF CANCER
- The Role of EphA4 Signaling in Radiation-Induced EMT-Like Phenotype in Colorectal Cancer Cells
- (2016) Priscila Guimarães de Marcondes et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- UVA-Irradiation Induces Melanoma Invasion via the Enhanced Warburg Effect
- (2016) York Kamenisch et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Hypoxia-inducible factor 1–mediated characteristic features of cancer cells for tumor radioresistance
- (2016) Hiroshi Harada JOURNAL OF RADIATION RESEARCH
- Bypassing Mechanisms of Mitochondria-Mediated Cancer Stem Cells Resistance to Chemo- and Radiotherapy
- (2016) Alex Lyakhovich et al. Oxidative Medicine and Cellular Longevity
- Radiation Exposure Promotes Hepatocarcinoma Cell Invasion through Epithelial Mesenchymal Transition Mediated by H2S/CSE Pathway
- (2016) Yan Pan et al. RADIATION RESEARCH
- Hypoxic control of metastasis
- (2016) E. B. Rankin et al. SCIENCE
- Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program
- (2016) Esther Aguilar et al. STEM CELLS
- The long non-coding RNA NEAT1 regulates epithelial to mesenchymal transition and radioresistance in through miR-204/ZEB1 axis in nasopharyngeal carcinoma
- (2016) Yaoyong Lu et al. TUMOR BIOLOGY
- Long non-coding RNA regulation of epithelial–mesenchymal transition in cancer metastasis
- (2016) Q Xu et al. Cell Death & Disease
- Estradiol, TGF-β1 and hypoxia promote breast cancer stemness and EMT-mediated breast cancer migration
- (2016) SEONG-JOON PARK et al. Oncology Letters
- LIG4 mediates Wnt signalling-induced radioresistance
- (2016) Sohee Jun et al. Nature Communications
- A FASN-TGF-β1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer
- (2016) Li Yang et al. Oncotarget
- Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch
- (2016) Su Yeon Lee et al. Oncotarget
- Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer
- (2016) Anatilde M. Gonzalez-Guerrico et al. Oncotarget
- MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
- (2016) Xiaoran Li et al. Oncotarget
- Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling
- (2016) Xiaoqing Wu et al. Oncotarget
- Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer
- (2016) Yang Chen et al. Oncotarget
- Plasminogen activator inhibitor-1 enhances radioresistance and aggressiveness of non-small cell lung cancer cells
- (2016) JiHoon Kang et al. Oncotarget
- DANGER is involved in high glucose-induced radioresistance through inhibiting DAPK-mediated anoikis in non-small cell lung cancer
- (2016) TaeWoo Kwon et al. Oncotarget
- Role of ADAM17 in invasion and migration of CD133-expressing liver cancer stem cells after irradiation
- (2016) SungWoo Hong et al. Oncotarget
- Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer
- (2016) Rae-Kwon Kim et al. Oncotarget
- LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells
- (2016) Zhen Wei Zou et al. Oncotarget
- FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells
- (2016) Uday B. Maachani et al. Oncotarget
- Noncoding RNAs in Tumor Epithelial-to-Mesenchymal Transition
- (2016) Ching-Wen Lin et al. Stem Cells International
- Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment
- (2016) Natacha Leroi et al. Frontiers in Pharmacology
- The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect
- (2016) Min Wang et al. PeerJ
- Smad2/3-Regulated Expression of DLX2 Is Associated with Radiation-Induced Epithelial-Mesenchymal Transition and Radioresistance of A549 and MDA-MB-231 Human Cancer Cell Lines
- (2016) Yeo-Jin Choi et al. PLoS One
- Ionizing Radiation Induces Myofibroblast Differentiation via Lactate Dehydrogenase
- (2015) Jennifer L Judge et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Silibinin attenuates ionizing radiation-induced pro-angiogenic response and EMT in prostate cancer cells
- (2015) Dhanya K. Nambiar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells
- (2015) Anant Narayan Bhatt et al. BMC CANCER
- Epithelial–mesenchymal transition induces similar metabolic alterations in two independent breast cancer cell lines
- (2015) Yuvabharath Kondaveeti et al. CANCER LETTERS
- Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo
- (2015) Mao-Bin Meng et al. CANCER LETTERS
- Metabolic reprogramming supports the invasive phenotype in malignant melanoma
- (2015) Ingrid J. Bettum et al. CANCER LETTERS
- The Warburg effect in tumor progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism
- (2015) Jianrong Lu et al. CANCER LETTERS
- Aldehyde Dehydrogenase Is Regulated by -Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells
- (2015) M. Cojoc et al. CANCER RESEARCH
- TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells
- (2015) ZhengMing Wu et al. Cell Stem Cell
- Ionizing radiation induces a motile phenotype in human carcinoma cells in vitro through hyperactivation of the TGF-beta signaling pathway
- (2015) Cedric Carl et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Targeting PI3K/Akt/mTOR signaling pathway in the treatment of prostate cancer radioresistance
- (2015) Lei Chang et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Dichloroacetate alters Warburg metabolism, inhibits cell growth, and increases the X-ray sensitivity of human A549 and H1299 NSC lung cancer cells
- (2015) Kah Tan Allen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer
- (2015) Aki Miyasaka et al. GYNECOLOGIC ONCOLOGY
- Nijmegen breakage syndrome protein 1 (NBS1) modulates hypoxia inducible factor-1α (HIF-1α) stability and promotes in vitro migration and invasion under ionizing radiation
- (2015) Yi-Chih Kuo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Dlx-2 is implicated in TGF-β- and Wnt-induced epithelial-mesenchymal, glycolytic switch, and mitochondrial repression by Snail activation
- (2015) SU YEON LEE et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans
- (2015) Lisa M. Abegglen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies
- (2015) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
- (2015) Ibtissam Marchiq et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The role of CD29-ILK-Akt signaling-mediated epithelial–mesenchymal transition of liver epithelial cells and chemoresistance and radioresistance in hepatocellular carcinoma cells
- (2015) Xiaorong Jiang et al. MEDICAL ONCOLOGY
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Radiation promotes invasiveness of non-small-cell lung cancer cells through granulocyte-colony-stimulating factor
- (2015) Y-H Cui et al. ONCOGENE
- EGFR targeted therapies and radiation: Optimizing efficacy by appropriate drug scheduling and patient selection
- (2015) Kyle C. Cuneo et al. PHARMACOLOGY & THERAPEUTICS
- Targeting the TGFβ pathway for cancer therapy
- (2015) Cindy Neuzillet et al. PHARMACOLOGY & THERAPEUTICS
- Cancer across the tree of life: cooperation and cheating in multicellularity
- (2015) C. A. Aktipis et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation
- (2015) Enhui He et al. PLoS One
- IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation
- (2015) Yuhchyau Chen et al. Radiation Oncology
- Energy Metabolism in a Matched Model of Radiation Resistance for Head and Neck Squamous Cell Cancer
- (2015) Jade Mims et al. RADIATION RESEARCH
- Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production
- (2015) Klaus Dittmann et al. RADIOTHERAPY AND ONCOLOGY
- A role for cancer stem cells in therapy resistance: Cellular and molecular mechanisms
- (2015) Monica Cojoc et al. SEMINARS IN CANCER BIOLOGY
- Dysregulated metabolism contributes to oncogenesis
- (2015) Matthew D. Hirschey et al. SEMINARS IN CANCER BIOLOGY
- Wnt/β-catenin pathway involvement in ionizing radiation-induced invasion of U87 glioblastoma cells
- (2015) Zhen Dong et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Γ-Ionizing radiation-induced activation of the EGFR–p38/ERK–STAT3/CREB-1–EMT pathway promotes the migration/invasion of non-small cell lung cancer cells and is inhibited by podophyllotoxin acetate
- (2015) Jeong Hyun Cho et al. TUMOR BIOLOGY
- The role of MALAT1/miR-1/slug axis on radioresistance in nasopharyngeal carcinoma
- (2015) Chuan Jin et al. TUMOR BIOLOGY
- Links between cancer stem cells and epithelial– mesenchymal transition
- (2015) Yaling Tang et al. OncoTargets and Therapy
- Role of matrix metalloproteinases in radiation-induced lung injury in alveolar epithelial cells of Bama minipigs
- (2015) HAIYING YUE et al. Experimental and Therapeutic Medicine
- Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma
- (2015) Chang-Lung Lee et al. Nature Communications
- Manipulation of tumor metabolism for therapeutic approaches: ovarian cancer-derived cell lines as a model system
- (2015) Kristina Goetze et al. CELLULAR ONCOLOGY
- Cancer stem cell targeted therapy: progress amid controversies
- (2015) Tao Wang et al. Oncotarget
- Hypoxia-inducible factor 1α (HIF-1α) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1α/CXCR4 pathway in non-small cell lung carcinoma cells
- (2015) Qing Gu et al. Oncotarget
- Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells
- (2015) Wei-Hsiu Liu et al. Oncotarget
- Cancer stem cell related markers of radioresistance in head and neck squamous cell carcinoma
- (2015) Ina Kurth et al. Oncotarget
- Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition
- (2015) Roberto Gomez-Casal et al. Oncotarget
- Invasive oral cancer stem cells display resistance to ionising radiation
- (2015) Emilios Gemenetzidis et al. Oncotarget
- Notch and Wnt/β-catenin signaling pathway play important roles in activating liver cancer stem cells
- (2015) Ronghua Wang et al. Oncotarget
- Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy
- (2015) Doudou Li et al. Oncotarget
- EMT, CTCs and CSCs in tumor relapse and drug-resistance
- (2015) Abhisek Mitra et al. Oncotarget
- Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells
- (2015) Maria Peiris-Pagès et al. Oncotarget
- The Notch pathway promotes the cancer stem cell characteristics of CD90+ cells in hepatocellular carcinoma
- (2015) Jing Luo et al. Oncotarget
- 5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits
- (2015) Corti Denise et al. Oncotarget
- The roles of microRNAs in the regulation of tumor metastasis
- (2015) Lei Zhou et al. Cell and Bioscience
- Cancer stem cell plasticity and tumor hierarchy
- (2015) Marina Carla Cabrera World Journal of Stem Cells
- Role of Bmi-1 in Regulation of Ionizing Irradiation-Induced Epithelial-Mesenchymal Transition and Migration of Breast Cancer Cells
- (2015) Weiwei Yuan et al. PLoS One
- Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells
- (2015) Phatchariya Phannasil et al. PLoS One
- B7H1 Expression and Epithelial-To-Mesenchymal Transition Phenotypes on Colorectal Cancer Stem-Like Cells
- (2015) Yidan Zhi et al. PLoS One
- FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2
- (2015) Yeri Lee et al. PLoS One
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Trimodal Glioblastoma Treatment Consisting of Concurrent Radiotherapy, Temozolomide, and the Novel TGF-β Receptor I Kinase Inhibitor LY2109761
- (2015) Mengxian Zhang et al. NEOPLASIA
- The metabolic cooperation between cells in solid cancer tumors
- (2014) Philippe Icard et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Cancer Stem Cells and Regulatory RNAs Crosstalk: Fostering Possibilities for Cancer Therapies
- (2014) Zhumur Ghosh et al. BIOSCIENCE
- Emerging roles of radioresistance in prostate cancer metastasis and radiation therapy
- (2014) Lei Chang et al. CANCER AND METASTASIS REVIEWS
- PAK1 Tyrosine Phosphorylation Is Required to Induce Epithelial-Mesenchymal Transition and Radioresistance in Lung Cancer Cells
- (2014) E. Kim et al. CANCER RESEARCH
- Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers
- (2014) G. N. Gan et al. CANCER RESEARCH
- Radiation promotes malignant phenotypes through SRC in breast cancer cells
- (2014) Rae-Kwon Kim et al. CANCER SCIENCE
- Radiotherapy-induced plasticity of prostate cancer mobilizes stem-like non-adherent, Erk signaling-dependent cells
- (2014) L Kyjacova et al. CELL DEATH AND DIFFERENTIATION
- Radiation-enhanced cell migration/invasion process: A review
- (2014) Coralie Moncharmont et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- The Role of Snail in EMT and Tumorigenesis
- (2014) Yifan Wang et al. CURRENT CANCER DRUG TARGETS
- Wnt meets Warburg: another piece in the puzzle?
- (2014) C. B. Thompson EMBO JOURNAL
- Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer
- (2014) K. T. Pate et al. EMBO JOURNAL
- Oral epithelial stem cells—Implications in normal development and cancer metastasis
- (2014) Silvana Papagerakis et al. EXPERIMENTAL CELL RESEARCH
- Loss of -catenin triggers oxidative stress and impairs hematopoietic regeneration
- (2014) W. Lento et al. GENES & DEVELOPMENT
- Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT-LikePhenotype and Activate Wnt/β-Catenin Pathway
- (2014) Lilian Gonçalves dos Reis Bastos et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Role of the epidermal growth factor receptor in ultraviolet radiation induction of Snail family transcription factors
- (2014) Stephanie H. Shirley et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Inhibition of TBK1 attenuates radiation-induced epithelial–mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1
- (2014) Wen Liu et al. LABORATORY INVESTIGATION
- WNT Signaling: an Emerging Mediator of Cancer Cell Metabolism?
- (2014) Victoria Sherwood MOLECULAR AND CELLULAR BIOLOGY
- TGFβ1 Protects Cells from γ-IR by Enhancing the Activity of the NHEJ Repair Pathway
- (2014) Mi-Ra Kim et al. MOLECULAR CANCER RESEARCH
- Inhibition of Monocarboxylate Transporter-1 (MCT1) by AZD3965 Enhances Radiosensitivity by Reducing Lactate Transport
- (2014) B. M. Bola et al. MOLECULAR CANCER THERAPEUTICS
- Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
- (2014) Allison S. Cleary et al. NATURE
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
- (2014) Peijing Zhang et al. NATURE CELL BIOLOGY
- Oncogenic roles of EMT-inducing transcription factors
- (2014) Alain Puisieux et al. NATURE CELL BIOLOGY
- Tackling the cancer stem cells — what challenges do they pose?
- (2014) Diwakar R. Pattabiraman et al. NATURE REVIEWS DRUG DISCOVERY
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeting glucose metabolism in chondrosarcoma cells enhances the sensitivity to doxorubicin through the inhibition of lactate dehydrogenase-A
- (2014) GUOJUN HUA et al. ONCOLOGY REPORTS
- Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition
- (2014) A. Hamabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance
- (2014) Jie Ni et al. PROSTATE
- CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells
- (2014) Amar Desai et al. RADIOTHERAPY AND ONCOLOGY
- Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
- (2014) Ubaldo E. Martinez-Outschoorn et al. SEMINARS IN CANCER BIOLOGY
- Tumor Microenvironment and Metabolic Synergy in Breast Cancers: Critical Importance of Mitochondrial Fuels and Function
- (2014) Ubaldo Martinez-Outschoorn et al. SEMINARS IN ONCOLOGY
- Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling
- (2014) X Peng et al. Cell Death & Disease
- Radiation induces senescence and a bystander effect through metabolic alterations
- (2014) E-C Liao et al. Cell Death & Disease
- Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
- (2014) D Ciavardelli et al. Cell Death & Disease
- miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13
- (2014) Peijing Zhang et al. Nature Communications
- Heterogeneous Tumor Subpopulations Cooperate to Drive Invasion
- (2014) Anna Chapman et al. Cell Reports
- The role of microRNAs in the regulation of cancer stem cells
- (2014) Ryou-u Takahashi et al. Frontiers in Genetics
- EMT or EMT-Promoting Transcription Factors, Where to Focus the Light?
- (2014) Stéphane Ansieau et al. Frontiers in Oncology
- Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment
- (2014) Martin Augsten Frontiers in Oncology
- Ionizing Radiation-Induced DNA Damage, Response, and Repair
- (2013) Wil L. Santivasi et al. ANTIOXIDANTS & REDOX SIGNALING
- CD24+ ovary cancer cells exhibit an invasive mesenchymal phenotype
- (2013) Kyu Sub Kang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The inhibition of migration and invasion of cancer cells by graphene via the impairment of mitochondrial respiration
- (2013) Hejiang Zhou et al. BIOMATERIALS
- Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
- (2013) Chenfang Dong et al. CANCER CELL
- SnapShot: Cancer Metabolism Pathways
- (2013) Lydia W.S. Finley et al. Cell Metabolism
- The Hallmarks of Cancer and the Radiation Oncologist: Updating the 5Rs of Radiobiology
- (2013) J.S. Good et al. CLINICAL ONCOLOGY
- Targeting Hypoxia for Sensitization of Tumors to Radio- and Chemotherapy
- (2013) Khaled Ghattass et al. CURRENT CANCER DRUG TARGETS
- Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition
- (2013) David Balli et al. EMBO JOURNAL
- Acquisition of epithelial–mesenchymal transition phenotype and cancer stem cell-like properties in cisplatin-resistant lung cancer cells through AKT/β-catenin/Snail signaling pathway
- (2013) Hao Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effects of ionizing radiation on mitochondria
- (2013) Winnie Wai-Ying Kam et al. FREE RADICAL BIOLOGY AND MEDICINE
- Epithelial-mesenchymal plasticity in carcinoma metastasis
- (2013) J. H. Tsai et al. GENES & DEVELOPMENT
- Rhamnetin and Cirsiliol Induce Radiosensitization and Inhibition of Epithelial-Mesenchymal Transition (EMT) by miR-34a-mediated Suppression of Notch-1 Expression in Non-small Cell Lung Cancer Cell Lines
- (2013) JiHoon Kang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Radiation and immunotherapy: a synergistic combination
- (2013) Anusha Kalbasi et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of N-acetyl-l-cysteine on adhesive strength between breast cancer cell and extracellular matrix proteins after ionizing radiation
- (2013) Huiwen Cheng et al. LIFE SCIENCES
- Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes
- (2013) Roberto Gomez-Casal et al. Molecular Cancer
- Influence of tumour micro-environment heterogeneity on therapeutic response
- (2013) Melissa R. Junttila et al. NATURE
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma
- (2013) Roshan Mahabir et al. NEURO-ONCOLOGY
- MicroRNAs and cancer stem cells: the sword and the shield
- (2013) X Sun et al. ONCOGENE
- ErbB2, FoxM1 and 14-3-3ζ prime breast cancer cells for invasion in response to ionizing radiation
- (2013) D M Kambach et al. ONCOGENE
- Immunosuppressive networks and checkpoints controlling antitumor immunity and their blockade in the development of cancer immunotherapeutics and vaccines
- (2013) A Q Butt et al. ONCOGENE
- Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells
- (2013) XIAOMING ZHAI et al. ONCOLOGY REPORTS
- Prognostic value of mitochondrial DNA content and G10398A polymorphism in non-small cell lung cancer
- (2013) HUI XU et al. ONCOLOGY REPORTS
- Mechanisms of Injury to Normal Tissue after Radiotherapy
- (2013) Justin R. Hubenak et al. PLASTIC AND RECONSTRUCTIVE SURGERY
- A Role of TGFß1 Dependent 14-3-3σ Phosphorylation at Ser69 and Ser74 in the Regulation of Gene Transcription, Stemness and Radioresistance
- (2013) Olena Zakharchenko et al. PLoS One
- Potential Role of Hedgehog Pathway in Liver Response to Radiation
- (2013) Sihyung Wang et al. PLoS One
- Radiation induces aerobic glycolysis through reactive oxygen species
- (2013) Jim Zhong et al. RADIOTHERAPY AND ONCOLOGY
- Interaction of EGFR with the tumour microenvironment: Implications for radiation treatment
- (2013) Monique M. Nijkamp et al. RADIOTHERAPY AND ONCOLOGY
- Tumors as Organs: Biologically Augmenting Radiation Therapy by Inhibiting Transforming Growth Factor β Activity in Carcinomas
- (2013) Shisuo Du et al. SEMINARS IN RADIATION ONCOLOGY
- Increased expression of DLX2 correlates with advanced stage of gastric adenocarcinoma
- (2013) Peng Tang WORLD JOURNAL OF GASTROENTEROLOGY
- Targeting cellular metabolism to improve cancer therapeutics
- (2013) Y Zhao et al. Cell Death & Disease
- Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance
- (2013) L Chang et al. Cell Death & Disease
- Effect of AKT inhibition on epithelial-mesenchymal transition and ZEB1-potentiated radiotherapy in nasopharyngeal carcinoma
- (2013) WEIGUO CHEN et al. Oncology Letters
- Ionizing radiation, ion transports, and radioresistance of cancer cells
- (2013) Stephan M. Huber et al. Frontiers in Physiology
- Immunosuppressive Microenvironment in Neuroblastoma
- (2013) Vito Pistoia et al. Frontiers in Oncology
- MicroRNAs involved in regulating epithelial–mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics
- (2012) H Xia et al. CANCER GENE THERAPY
- Cancer stem cells, the epithelial to mesenchymal transition (EMT) and radioresistance: Potential role of hypoxia
- (2012) Delphine Tamara Marie-Egyptienne et al. CANCER LETTERS
- Why does cancer therapy lack effective anti-metastasis drugs?
- (2012) Georg F. Weber CANCER LETTERS
- MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells
- (2012) W.-J. Wang et al. CANCER RESEARCH
- Wnt/Snail Signaling Regulates Cytochrome c Oxidase and Glucose Metabolism
- (2012) S. Y. Lee et al. CANCER RESEARCH
- Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β
- (2012) Matthew E. Hardee et al. CANCER RESEARCH
- Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity
- (2012) Appalaraju Jaggupilli et al. Clinical & Developmental Immunology
- Molecular Pathways: Emerging Pathways Mediating Growth, Invasion, and Metastasis of Tumors Progressing in an Irradiated Microenvironment
- (2012) F. Kuonen et al. CLINICAL CANCER RESEARCH
- Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy
- (2012) T. W. H. Meijer et al. CLINICAL CANCER RESEARCH
- Multiple Biological Activities of Lactic Acid in Cancer: Influences on Tumor Growth,Angiogenesis and Metastasis
- (2012) Suveera Dhup et al. CURRENT PHARMACEUTICAL DESIGN
- Mutant p53: one name, many proteins
- (2012) W. A. Freed-Pastor et al. GENES & DEVELOPMENT
- Links between metabolism and cancer
- (2012) C. V. Dang GENES & DEVELOPMENT
- Cancer stem cells
- (2012) Zuoren Yu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
- (2012) Toni Celià-Terrassa et al. JOURNAL OF CLINICAL INVESTIGATION
- Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy
- (2012) Kazuhiko Shien et al. LUNG CANCER
- Hypoxia Modulates A431 Cellular Pathways Association to Tumor Radioresistance and Enhanced Migration Revealed by Comprehensive Proteomic and Functional Studies
- (2012) Yan Ren et al. MOLECULAR & CELLULAR PROTEOMICS
- Epigenetic alterations involved in cancer stem cell reprogramming
- (2012) Purificación Muñoz et al. Molecular Oncology
- How cancer metabolism is tuned for proliferation and vulnerable to disruption
- (2012) Almut Schulze et al. NATURE
- Various modes of cell death induced by DNA damage
- (2012) O Surova et al. ONCOGENE
- Ionizing Radiation Induces Stemness in Cancer Cells
- (2012) Laura Ghisolfi et al. PLoS One
- Long-term recovery of irradiated prostate cancer increases cancer stem cells
- (2012) Yong Mee Cho et al. PROSTATE
- Establishment of animal model for the analysis of cancer cell metastasis during radiotherapy
- (2012) Jong Park et al. Radiation Oncology
- Cancer stem cells and epithelial–mesenchymal transition: Concepts and molecular links
- (2012) Christina Scheel et al. SEMINARS IN CANCER BIOLOGY
- Mevalonate Metabolism Regulates Basal Breast Cancer Stem Cells and Is a Potential Therapeutic Target
- (2012) Christophe Ginestier et al. STEM CELLS
- Radiation-Induced Reprogramming of Breast Cancer Cells
- (2012) Chann Lagadec et al. STEM CELLS
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells
- (2012) J Cahu et al. Cell Death & Disease
- Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels
- (2012) Hiroshi Harada et al. Nature Communications
- Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy
- (2012) Chin-Chih Lin et al. Scientific Reports
- Translating the combination of TGFβ blockade and radiotherapy into clinical development in glioblastoma
- (2012) Mengxian Zhang et al. OncoImmunology
- Radiation-Induced Increase in Cell Migration and Metastatic Potential of Cervical Cancer Cells Operates Via the K-Ras Pathway
- (2011) Wen-Hong Su et al. AMERICAN JOURNAL OF PATHOLOGY
- Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial–mesenchymal transition
- (2011) Xin Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways
- (2011) Anja C Pickhard et al. BMC CANCER
- CD133+ liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma
- (2011) Lian Shu Piao et al. CANCER LETTERS
- Dispersal Evolution in Neoplasms: The Role of Disregulated Metabolism in the Evolution of Cell Motility
- (2011) C. A. Aktipis et al. Cancer Prevention Research
- Lactate: A Metabolic Key Player in Cancer
- (2011) F. Hirschhaeuser et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
- (2011) Stephanos Pavlides et al. CELL CYCLE
- TGF 1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo
- (2011) F. Bouquet et al. CLINICAL CANCER RESEARCH
- Transcription factor Dlx2 protects from TGFβ-induced cell-cycle arrest and apoptosis
- (2011) Mahmut Yilmaz et al. EMBO JOURNAL
- ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition
- (2011) Devipriya Nagarajan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial dysfunction, a probable cause of persistent oxidative stress after exposure to ionizing radiation
- (2011) Takako Yoshida et al. FREE RADICAL RESEARCH
- SNAIL Regulates Interleukin-8 Expression, Stem Cell–Like Activity, and Tumorigenicity of Human Colorectal Carcinoma Cells
- (2011) Wei–Lun Hwang et al. GASTROENTEROLOGY
- Ionizing Radiation Promotes Migration and Invasion of Cancer Cells Through Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition
- (2011) Yong-Chun Zhou et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
- (2011) Ardian Latifi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- How Can We Overcome Tumor Hypoxia in Radiation Therapy?
- (2011) Hiroshi HARADA JOURNAL OF RADIATION RESEARCH
- Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer
- (2011) Francesca De Bacco et al. JNCI-Journal of the National Cancer Institute
- Mouse Snail Is a Target Gene for HIF
- (2011) D. Luo et al. MOLECULAR CANCER RESEARCH
- Radioresistance of glioma stem cells: Intrinsic characteristic or property of the ‘microenvironment-stem cell unit’?
- (2011) Mariella Mannino et al. Molecular Oncology
- Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9–mediated EMT
- (2011) Swapna Asuthkar et al. NEURO-ONCOLOGY
- MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis
- (2011) C H Chou et al. ONCOGENE
- Radiation induces epithelial-mesenchymal transition in colorectal cancer cells
- (2011) Aya Kawamoto ONCOLOGY REPORTS
- Epithelial to Mesenchymal Transition by TGFβ-1 Induction Increases Stemness Characteristics in Primary Non Small Cell Lung Cancer Cell Line
- (2011) Giuseppe Pirozzi et al. PLoS One
- Radiation–Induced Signaling Results in Mitochondrial Impairment in Mouse Heart at 4 Weeks after Exposure to X-Rays
- (2011) Zarko Barjaktarovic et al. PLoS One
- Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
- (2011) C. L. Chaffer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
- (2010) Y Wu et al. BRITISH JOURNAL OF CANCER
- Metastasis: cancer cell’s escape from oxidative stress
- (2010) Giovambattista Pani et al. CANCER AND METASTASIS REVIEWS
- Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized
- (2010) Elsa Quintana et al. CANCER CELL
- Bcl-XL and STAT3 mediate malignant actions of γ-irradiation in lung cancer cells
- (2010) Jin-Nyoung Ho et al. CANCER SCIENCE
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- The reverse Warburg Effect: Glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts
- (2010) Gloria Bonuccelli et al. CELL CYCLE
- Ketones and lactate “fuel” tumor growth and metastasis
- (2010) Gloria Bonuccelli et al. CELL CYCLE
- HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells
- (2010) Barbara Chiavarina et al. CELL CYCLE
- Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the “reverse Warburg effect”: A transcriptional informatics analysis with validation
- (2010) Stephanos Pavlides et al. CELL CYCLE
- CD44 Expression Predicts Local Recurrence after Radiotherapy in Larynx Cancer
- (2010) M. C. de Jong et al. CLINICAL CANCER RESEARCH
- Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance
- (2010) Zhiwei Wang et al. DRUG RESISTANCE UPDATES
- Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
- (2010) Mitomu Kioi et al. JOURNAL OF CLINICAL INVESTIGATION
- UV irradiation induces Snail expression by AP-1 dependent mechanism in human skin keratinocytes
- (2010) Yong Li et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Changes of Circulating Transforming Growth Factor-²1 Level During Radiation Therapy Are Correlated with the Prognosis of Locally Advanced Non-small Cell Lung Cancer
- (2010) Lujun Zhao et al. Journal of Thoracic Oncology
- Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
- (2010) Ming Zhou et al. Molecular Cancer
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells
- (2010) M-Q Gao et al. ONCOGENE
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Links between Innate Immunity and Normal Tissue Radiobiology
- (2010) Dörthe Schaue et al. RADIATION RESEARCH
- ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway
- (2010) Mahmoud Toulany et al. RADIOTHERAPY AND ONCOLOGY
- Pathogenetic mechanisms in radiation fibrosis
- (2010) John Yarnold et al. RADIOTHERAPY AND ONCOLOGY
- Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
- (2010) Robert B. Hamanaka et al. TRENDS IN BIOCHEMICAL SCIENCES
- Stromal Cell Expression of Caveolin-1 Predicts Outcome in Breast Cancer
- (2009) Erica K. Sloan et al. AMERICAN JOURNAL OF PATHOLOGY
- An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers
- (2009) Agnieszka K. Witkiewicz et al. AMERICAN JOURNAL OF PATHOLOGY
- Redox-Based Escape Mechanism from Death: The Cancer Lesson
- (2009) Giovambattista Pani et al. ANTIOXIDANTS & REDOX SIGNALING
- Epithelial–Mesenchymal Transition: From Molecular Mechanisms, Redox Regulation to Implications in Human Health and Disease
- (2009) Stefania Cannito et al. ANTIOXIDANTS & REDOX SIGNALING
- Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion
- (2009) Yadi Wu et al. CANCER CELL
- Long noncoding RNAs: functional surprises from the RNA world
- (2009) J. E. Wilusz et al. GENES & DEVELOPMENT
- The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells
- (2009) Stephanie L. Lomonaco et al. INTERNATIONAL JOURNAL OF CANCER
- Aldehyde Dehydrogenase 1 Is a Tumor Stem Cell-Associated Marker in Lung Cancer
- (2009) F. Jiang et al. MOLECULAR CANCER RESEARCH
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
- (2009) Ulrich Wellner et al. NATURE CELL BIOLOGY
- Cancer stem cells: mirage or reality?
- (2009) Piyush B Gupta et al. NATURE MEDICINE
- SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer
- (2009) A. E. Sayan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
- (2009) G. Bertolini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glycolytic metabolism and tumour response to fractionated irradiation
- (2009) Ulrike G.A. Sattler et al. RADIOTHERAPY AND ONCOLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells
- (2009) Nawneet K. Kurrey et al. STEM CELLS
- Notch Promotes Radioresistance of Glioma Stem Cells
- (2009) Jialiang Wang et al. STEM CELLS
- Epithelial-Mesenchymal Transition Induced by Growth Suppressor p12CDK2-AP1 Promotes Tumor Cell Local Invasion but Suppresses Distant Colony Growth
- (2008) T. Tsuji et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- The Akt/mTOR Pathway Assures the Synthesis of HIF-1α Protein in a Glucose- and Reoxygenation-dependent Manner in Irradiated Tumors
- (2008) Hiroshi Harada et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis
- (2008) M. Escriva et al. MOLECULAR AND CELLULAR BIOLOGY
- Activation of Epidermal Growth Factor Receptor and Its Downstream Signaling Pathway by Nitric Oxide in Response to Ionizing Radiation
- (2008) H.-C. Lee et al. MOLECULAR CANCER RESEARCH
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