Rhamnetin and Cirsiliol Induce Radiosensitization and Inhibition of Epithelial-Mesenchymal Transition (EMT) by miR-34a-mediated Suppression of Notch-1 Expression in Non-small Cell Lung Cancer Cell Lines
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Title
Rhamnetin and Cirsiliol Induce Radiosensitization and Inhibition of Epithelial-Mesenchymal Transition (EMT) by miR-34a-mediated Suppression of Notch-1 Expression in Non-small Cell Lung Cancer Cell Lines
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 288, Issue 38, Pages 27343-27357
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2013-08-01
DOI
10.1074/jbc.m113.490482
References
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Note: Only part of the references are listed.- Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells
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- (2012) Luqing Zhao et al. CARCINOGENESIS
- Notch signaling mediates TGF-β1-induced epithelial–mesenchymal transition through the induction of Snai1
- (2012) Yosuke Matsuno et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- (2012) Woo Jae Kim et al. MOLECULAR CELL
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- (2011) M. Wang et al. CANCER RESEARCH
- A Genome-Wide Search for Promoters That Respond to Increased MYCN Reveals Both New Oncogenic and Tumor Suppressor MicroRNAs Associated with Aggressive Neuroblastoma
- (2011) J. M. Shohet et al. CANCER RESEARCH
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- (2011) Pek Keng Koh et al. CANCER TREATMENT REVIEWS
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- (2010) S. Saad et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- (2010) S Eliasz et al. ONCOGENE
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- (2010) Luca Toschi et al. Targeted Oncology
- Targeting Heat Shock Protein 90 Overrides the Resistance of Lung Cancer Cells by Blocking Radiation-Induced Stabilization of Hypoxia-Inducible Factor-1α
- (2009) Woo-Young Kim et al. CANCER RESEARCH
- The miR-34 family in cancer and apoptosis
- (2009) H Hermeking CELL DEATH AND DIFFERENTIATION
- The autonomous notch signal pathway is activated by baicalin and baicalein but is suppressed by niclosamide in K562 cells
- (2009) An-Ming Wang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2009) Guowei HUANG et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
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- (2009) Britta Westhoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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