Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma

Trimodal Glioblastoma Treatment Consisting of Concurrent Radiotherapy, Temozolomide, and the Novel TGF-β Receptor I Kinase Inhibitor LY2109761

(2015) Mengxian Zhang et al.   NEOPLASIA

Toll-Like Receptor-Mediated Production of IL-1Ra Is Negatively Regulated by GSK3 via the MAPK ERK1/2

(2014) K. Rehani et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma

(2012) Masaya Nagaishi et al.   BRAIN PATHOLOGY

Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition

(2012) Ulf D. Kahlert et al.   CANCER LETTERS

Molecular Pathways: Targeting the TGF-  Pathway for Cancer Therapy

(2012) A. L. Smith et al.   CLINICAL CANCER RESEARCH

STAT3 Inhibition Overcomes Temozolomide Resistance in Glioblastoma by Downregulating MGMT Expression

(2012) Shinji Kohsaka et al.   MOLECULAR CANCER THERAPEUTICS

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

(2012) Sabine Stolzenburg et al.   NUCLEIC ACIDS RESEARCH

ZEB2 Mediates Multiple Pathways Regulating Cell Proliferation, Migration, Invasion, and Apoptosis in Glioma

(2012) Songtao Qi et al.   PLoS One

Slug, Twist, and E-Cadherin as Immunohistochemical Biomarkers in Meningeal Tumors

(2012) Masaya Nagaishi et al.   PLoS One

A Simplified Approach for the Molecular Classification of Glioblastomas

(2012) Marie Le Mercier et al.   PLoS One

Cancer treatments transform residual cancer cell phenotype

(2011) William W Harless   Cancer Cell International

mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways

(2011) P. Gulhati et al.   CANCER RESEARCH

Blockade of TGF-  Signaling by the TGF R-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma

(2011) M. Zhang et al.   CANCER RESEARCH

The EMT regulator slug and lung carcinogenesis

(2011) J.-Y. Shih et al.   CARCINOGENESIS

SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells

(2011) Sung-Pil Han et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

ERK/GSK3β/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition

(2011) Devipriya Nagarajan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma

(2011) K. P. L. Bhat et al.   GENES & DEVELOPMENT

Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion

(2011) Mario A. Shields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNAI2/Slug promotes growth and invasion in human gliomas

(2010) Hong Wei Yang et al.   BMC CANCER

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks

(2010) Kouichi Tabu et al.   Molecular Cancer

TWIST1 promotes invasion through mesenchymal change in human glioblastoma

(2010) Svetlana A Mikheeva et al.   Molecular Cancer

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

(2009) Hiroaki Ikushima et al.   Cell Stem Cell

Increased Motility and Invasiveness in Tumor Cells That Survive 10 Gy Irradiation

(2009) Kaori Tsutsumi et al.   CELL STRUCTURE AND FUNCTION

EMT: When epithelial cells decide to become mesenchymal-like cells

(2009) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Adaptor Protein Crk Induces Src-Dependent Activation of p38 MAPK in Regulation of Synovial Sarcoma Cell Proliferation

(2009) T. Watanabe et al.   MOLECULAR CANCER RESEARCH

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Combination of Vascular Endothelial Growth Factor Receptor/Platelet-Derived Growth Factor Receptor Inhibition Markedly Improves Radiation Tumor Therapy

(2008) C. Timke et al.   CLINICAL CANCER RESEARCH

Transforming Growth Factor- 1 Promotes Matrix Metalloproteinase-9-Mediated Oral Cancer Invasion through Snail Expression

(2008) L. Sun et al.   MOLECULAR CANCER RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One