HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis
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Title
HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2016, Issue -, Pages 1-13
Publisher
Hindawi Limited
Online
2016-02-04
DOI
10.1155/2016/9012580
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Note: Only part of the references are listed.- NF-κB/RelA and Nrf2 cooperate to maintain hepatocyte integrity and to prevent development of hepatocellular adenoma
- (2016) Ulrike A. Köhler et al. JOURNAL OF HEPATOLOGY
- Inhibitory effects of Pycnogenol® on hepatitis C virus replication
- (2015) Sayeh Ezzikouri et al. ANTIVIRAL RESEARCH
- Characterization of -taxilin as a novel factor controlling the release of hepatitis C virus
- (2015) F. Elgner et al. BIOCHEMICAL JOURNAL
- Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways
- (2015) Joanna D. Wardyn et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention
- (2015) Bryan Harder et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic
- (2015) Maria A. O’Connell et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism
- (2015) Dionysios V. Chartoumpekis et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Hepatitis C virus and autophagy
- (2015) Linya Wang et al. BIOLOGICAL CHEMISTRY
- Autophagy and apoptosis in liver injury
- (2015) Kewei Wang CELL CYCLE
- p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
- (2015) Yoshinori Katsuragi et al. FEBS Journal
- p62 links autophagy and Nrf2 signaling
- (2015) Tao Jiang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular basis of the Keap1–Nrf2 system
- (2015) Takafumi Suzuki et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hepatitis C Virus Attenuates Mitochondrial Lipid β-Oxidation by Downregulating Mitochondrial Trifunctional-Protein Expression
- (2015) Yutaka Amako et al. JOURNAL OF VIROLOGY
- Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway
- (2015) Shubham Shrivastava et al. JOURNAL OF VIROLOGY
- PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins
- (2015) David G. McEwan et al. MOLECULAR CELL
- Hepatitis C virus and lipid droplets: finding a niche
- (2015) Ana Filipe et al. TRENDS IN MOLECULAR MEDICINE
- Hepatitis C virus comes for dinner: How the hepatitis C virus interferes with autophagy
- (2015) Daniela Ploen WORLD JOURNAL OF GASTROENTEROLOGY
- HCV Core Protein Uses Multiple Mechanisms to Induce Oxidative Stress in Human Hepatoma Huh7 Cells
- (2015) Alexander Ivanov et al. Viruses-Basel
- Structural and Functional Properties of the Hepatitis C Virus p7 Viroporin
- (2015) Vanesa Madan et al. Viruses-Basel
- HCV Induces the Expression of Rubicon and UVRAG to Temporally Regulate the Maturation of Autophagosomes and Viral Replication
- (2015) Linya Wang et al. PLoS Pathogens
- Differential effects of buffer pH on Ca2+-induced ROS emission with inhibited mitochondrial complexes I and III
- (2015) Daniel P. Lindsay et al. Frontiers in Physiology
- Antioxidant responses and cellular adjustments to oxidative stress
- (2015) Cristina Espinosa-Diez et al. Redox Biology
- Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression
- (2014) Ji Wang et al. Autophagy
- Oxidative stress and autophagy: the clash between damage and metabolic needs
- (2014) G Filomeni et al. CELL DEATH AND DIFFERENTIATION
- Hepatitis C Virus RNA Replication and Assembly: Living on the Fat of the Land
- (2014) David Paul et al. Cell Host & Microbe
- TIP47 is associated with the Hepatitis C virus and its interaction with Rab9 is required for release of viral particles
- (2014) Daniela Ploen et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics
- (2014) Anna-Liisa Levonen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Therapeutic targeting of GSK3β enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C
- (2014) Yongfang Jiang et al. GUT
- Glutathione peroxidase 4 is reversibly induced by HCV to control lipid peroxidation and to increase virion infectivity
- (2014) Charlène Brault et al. GUT
- Endoplasmic Reticulum Stress Links Hepatitis C Virus RNA Replication to Wild-Type PGC-1 /Liver-Specific PGC-1 Upregulation
- (2014) W. Yao et al. JOURNAL OF VIROLOGY
- Hepatitis C Virus NS5A Hijacks ARFGAP1 To Maintain a Phosphatidylinositol 4-Phosphate-Enriched Microenvironment
- (2014) H. Li et al. JOURNAL OF VIROLOGY
- Apolipoprotein E Likely Contributes to a Maturation Step of Infectious Hepatitis C Virus Particles and Interacts with Viral Envelope Glycoproteins
- (2014) J.-Y. Lee et al. JOURNAL OF VIROLOGY
- The adjuvant component α-tocopherol triggers via modulation of Nrf2 the expression and turnover of hypocretin in vitro and its implication to the development of narcolepsy
- (2014) Sanita Masoudi et al. VACCINE
- Autophagy in hepatitis C virus-host interactions: Potential roles and therapeutic targets for liver-associated diseases
- (2014) Po-Yuan Ke WORLD JOURNAL OF GASTROENTEROLOGY
- Membranous Replication Factories Induced by Plus-Strand RNA Viruses
- (2014) Inés Romero-Brey et al. Viruses-Basel
- ER stress, autophagy, and RNA viruses
- (2014) Jia-Rong Jheng et al. Frontiers in Microbiology
- The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts
- (2014) Kirsten Linhart et al. Redox Biology
- Role of NADPH Oxidases in Liver Fibrosis
- (2013) Yong-Han Paik et al. ANTIOXIDANTS & REDOX SIGNALING
- Calyxin Y induces hydrogen peroxide-dependent autophagy and apoptosis via JNK activation in human non-small cell lung cancer NCI-H460 cells
- (2013) Chao Zhang et al. CANCER LETTERS
- Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy
- (2013) Hadi Digaleh et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitochondrial reactive oxygen species as a mystery voice in hepatitis C
- (2013) Keisuke Hino et al. HEPATOLOGY RESEARCH
- Hepatitis C virus core protein induces hepatic metabolism disorders through down-regulation of the SIRT1–AMPK signaling pathway
- (2013) Jian-Wu Yu et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Diacylglycerol Acyltransferase-1 Localizes Hepatitis C Virus NS5A Protein to Lipid Droplets and Enhances NS5A Interaction with the Viral Capsid Core
- (2013) Gregory Camus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
- (2013) Yoshinobu Ichimura et al. MOLECULAR CELL
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
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- (2013) Lindsey M. Silva et al. SEMINARS IN CANCER BIOLOGY
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- (2013) Alexander Ivanov et al. Viruses-Basel
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- (2012) Isabel Pombo Grégoire et al. Autophagy
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- (2012) Shubham Shrivastava et al. JOURNAL OF VIROLOGY
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- (2012) Arwa S. Kathiria et al. PLoS One
- Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication
- (2012) Inés Romero-Brey et al. PLoS Pathogens
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- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)
- (2011) Tiziana Anelli et al. ANTIOXIDANTS & REDOX SIGNALING
- Autophagy: A novel guardian of HCV against innate immune response
- (2011) Po-Yuan Ke et al. Autophagy
- Selective autophagy mediated by autophagic adapter proteins
- (2011) Terje Johansen et al. Autophagy
- Targeting of the same proteins to multiple subcellular destinations: mechanisms and physiological implications
- (2011) Narayan G. Avadhani FEBS Journal
- Hepatitis C Virus Impairs the Induction of Cytoprotective Nrf2 Target Genes by Delocalization of Small Maf Proteins
- (2011) Monica Carvajal-Yepes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview
- (2011) Monica Marra et al. Journal of Translational Medicine
- Rab5 and Class III Phosphoinositide 3-Kinase Vps34 Are Involved in Hepatitis C Virus NS4B-Induced Autophagy
- (2011) W.-C. Su et al. JOURNAL OF VIROLOGY
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- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
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- (2011) Emmanuelle Merquiol et al. PLoS One
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- (2011) Alexander V. Ivanov et al. PLoS One
- Persistent Expression of Hepatitis C Virus Non-Structural Proteins Leads to Increased Autophagy and Mitochondrial Injury in Human Hepatoma Cells
- (2011) Victor C. Chu et al. PLoS One
- Hepatitis c virus and host cell lipids: An intimate connection
- (2011) Gualtiero Alvisi et al. RNA Biology
- Prohibitin is overexpressed in Huh-7-HCV and Huh-7.5-HCV cells harboring in vitro transcribed full-length hepatitis C virus RNA
- (2011) Shuang-Suo Dang et al. Virology Journal
- Impact of the Autophagy Machinery on Hepatitis C Virus Infection
- (2011) Marlène Dreux et al. Viruses-Basel
- IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network
- (2011) Isabel Pombo Grégoire et al. PLoS Pathogens
- Trafficking of Hepatitis C Virus Core Protein during Virus Particle Assembly
- (2011) Natalie A. Counihan et al. PLoS Pathogens
- Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
- (2010) Eisuke Itakura et al. Autophagy
- Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
- (2010) Weiliang Fan et al. Autophagy
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- (2010) Giuseppe Filomeni et al. Autophagy
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- (2010) Dale W. Hailey et al. CELL
- The cytoprotective Nrf2 transcription factor controls insulin receptor signaling in the regenerating liver
- (2010) Tobias A. Beyer et al. CELL CYCLE
- Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection
- (2010) Nabora Soledad Reyes de Mochel et al. HEPATOLOGY
- Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes
- (2010) Shubham Shrivastava et al. HEPATOLOGY
- Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway
- (2010) Ian M. Copple et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy
- (2010) Wei-Lien Yen et al. JOURNAL OF CELL BIOLOGY
- Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
- (2010) Kohichi Matsunaga et al. JOURNAL OF CELL BIOLOGY
- Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro
- (2010) Po-Yuan Ke et al. JOURNAL OF CLINICAL INVESTIGATION
- Ultrastructural and biochemical analyses of hepatitis C virus-associated host cell membranes
- (2010) P. Ferraris et al. JOURNAL OF GENERAL VIROLOGY
- In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C
- (2010) Tarik Asselah et al. JOURNAL OF PATHOLOGY
- Clinical and virological characteristics of chronic hepatitis B with concurrent hepatitis B E antigen and antibody detection
- (2010) J. Wang et al. JOURNAL OF VIRAL HEPATITIS
- Gene Expression Profiling Indicates the Roles of Host Oxidative Stress, Apoptosis, Lipid Metabolism, and Intracellular Transport Genes in the Replication of Hepatitis C Virus
- (2010) S. Blackham et al. JOURNAL OF VIROLOGY
- A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
- (2010) A. Lau et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2010) Shomit Sengupta et al. MOLECULAR CELL
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- Plasma membrane contributes to the formation of pre-autophagosomal structures
- (2010) Brinda Ravikumar et al. NATURE CELL BIOLOGY
- Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1
- (2010) Eva Herker et al. NATURE MEDICINE
- Assembly of infectious hepatitis C virus particles
- (2010) Ralf Bartenschlager et al. TRENDS IN MICROBIOLOGY
- Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection
- (2010) Carl Guévin et al. VIROLOGY
- Autophagy proteins promote hepatitis C virus replication
- (2009) Marlène Dreux et al. Autophagy
- Knockdown of autophagy-related gene decreases the production of infectious Hepatitis C virus particles
- (2009) Isei Tanida et al. Autophagy
- Superoxide is the major reactive oxygen species regulating autophagy
- (2009) Y Chen et al. CELL DEATH AND DIFFERENTIATION
- Autophagy, Immunity, and Microbial Adaptations
- (2009) Vojo Deretic et al. Cell Host & Microbe
- Insulin resistance and not steatosis is associated with modifications in oxidative stress markers in chronic hepatitis C, non-3 genotype
- (2009) Ana C. Oliveira et al. FREE RADICAL RESEARCH
- Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles
- (2009) Wagane J. A. Benga et al. HEPATOLOGY
- Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein
- (2009) Takeya Tsutsumi et al. HEPATOLOGY
- ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
- (2009) Ian G. Ganley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway
- (2009) D. Burdette et al. JOURNAL OF GENERAL VIROLOGY
- Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes
- (2009) Natalia Dionisio et al. JOURNAL OF HEPATOLOGY
- Role of Hepatitis C virus core protein in viral-induced mitochondrial dysfunction
- (2009) T. Wang et al. JOURNAL OF VIRAL HEPATITIS
- Hepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor -Dependent Manner: a New Contributor to HCV-Induced Oxidative Stress
- (2009) H. E. Boudreau et al. JOURNAL OF VIROLOGY
- The global burden of hepatitis C
- (2009) Daniel Lavanchy LIVER INTERNATIONAL
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- The autophagy machinery is required to initiate hepatitis C virus replication
- (2009) M. Dreux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-κB activation
- (2009) Shanshan Li et al. VIROLOGY
- Autophagy: A lysosomal degradation pathway with a central role in health and disease
- (2008) Eeva-Liisa Eskelinen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Impact of Oxidative Stress and Peroxisome Proliferator-Activated Receptor Coactivator-1 in Hepatic Insulin Resistance
- (2008) N. Kumashiro et al. DIABETES
- Decreased Expression of Cytochromes P450 1A2, 2E1, and 3A4 and Drug Transporters Na+-Taurocholate-Cotransporting Polypeptide, Organic Cation Transporter 1, and Organic Anion-Transporting Peptide-C Correlates with the Progression of Liver Fibrosis in Chronic Hepatitis C Patients
- (2008) K. Nakai et al. DRUG METABOLISM AND DISPOSITION
- Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response
- (2008) Donna Sir et al. HEPATOLOGY
- Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
- (2008) Elizabeth L. Axe et al. JOURNAL OF CELL BIOLOGY
- PPARα activation is essential for HCV core protein–induced hepatic steatosis and hepatocellular carcinoma in mice
- (2008) Naoki Tanaka et al. JOURNAL OF CLINICAL INVESTIGATION
- MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease
- (2008) M. Baril et al. JOURNAL OF VIROLOGY
- The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy
- (2008) Naonobu Fujita et al. MOLECULAR BIOLOGY OF THE CELL
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
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