HCV Causes Chronic Endoplasmic Reticulum Stress Leading to Adaptation and Interference with the Unfolded Protein Response

PERK and PKR: Old kinases learn new tricks

(2011) Jennifer F. Raven et al.   CELL CYCLE

Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1

(2010) Sampa Pal et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication

(2010) Annette von dem Bussche et al.   JOURNAL OF HEPATOLOGY

In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C

(2010) Tarik Asselah et al.   JOURNAL OF PATHOLOGY

Human Cytomegalovirus Induces the Endoplasmic Reticulum Chaperone BiP through Increased Transcription and Activation of Translation by Using the BiP Internal Ribosome Entry Site

(2010) N. J. Buchkovich et al.   JOURNAL OF VIROLOGY

Statins potentiate thein vitroanti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development

(2009) Leen Delang et al.   HEPATOLOGY

Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

(2009) Hervé Lerat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New and experimental therapies for HCV

(2009) Arema A. Pereira et al.   Nature Reviews Gastroenterology & Hepatology

Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans

(2009) C. Morck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-κB activation

(2009) Shanshan Li et al.   VIROLOGY

HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

(2009) Michael A. Joyce et al.   PLoS Pathogens

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

(2008) Donna Sir et al.   HEPATOLOGY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2

(2008) Ilya M Terenin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE