Therapeutic targeting of GSK3β enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C

Nuclear factor erythroid 2-like 2 (Nrf2) expression in end-stage liver disease

(2012) Mateusz Kurzawski et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/ -TrCP Axis

(2012) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes

(2011) Milad S. Bitar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age-related changes of Nrf2 and phosphorylated GSK-3β in a mouse model of accelerated aging (SAMP8)

(2011) Koji Tomobe et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Lithium in the treatment of neutropenia

(2011) Mario Petrini et al.   CURRENT OPINION IN HEMATOLOGY

Src Subfamily Kinases Regulate Nuclear Export and Degradation of Transcription Factor Nrf2 to Switch Off Nrf2-mediated Antioxidant Activation of Cytoprotective Gene Expression

(2011) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Impairs the Induction of Cytoprotective Nrf2 Target Genes by Delocalization of Small Maf Proteins

(2011) Monica Carvajal-Yepes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Hepatitis C Virus Proteins Activate NRF2/ARE Pathway by Distinct ROS-Dependent and Independent Mechanisms in HUH7 Cells

(2011) Alexander V. Ivanov et al.   PLoS One

TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells

(2010) Charalambos Michaeloudes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway

(2010) Hee Yeon Kay et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection

(2010) Nabora Soledad Reyes de Mochel et al.   HEPATOLOGY

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway

(2009) D. Burdette et al.   JOURNAL OF GENERAL VIROLOGY

The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection

(2009) Sandra Espada et al.   JOURNAL OF NEUROCHEMISTRY

Hepatitis C Virus Infection: Molecular Pathways to Steatosis, Insulin Resistance and Oxidative Stress

(2009) Sophie Clément et al.   Viruses-Basel

Glycogen Synthase Kinase 3β: A Novel Marker and Modulator of Inflammatory Injury in Chronic Renal Allograft Disease

(2008) R. Gong et al.   AMERICAN JOURNAL OF TRANSPLANTATION

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal celldeath

(2008) Ana I. Rojo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Hepatitis C Virus–Induced Reactive Oxygen Species Raise Hepatic Iron Level in Mice by Reducing Hepcidin Transcription

(2007) Sohji Nishina et al.   GASTROENTEROLOGY