Hepatitis C Virus NS5A Hijacks ARFGAP1 To Maintain a Phosphatidylinositol 4-Phosphate-Enriched Microenvironment

Role of Phosphatidylinositol 4-Phosphate (PI4P) and Its Binding Protein GOLPH3 in Hepatitis C Virus Secretion

(2012) Bryan Bishé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ARF1 and GBF1 Generate a PI4P-Enriched Environment Supportive of Hepatitis C Virus Replication

(2012) Leiliang Zhang et al.   PLoS One

Intrinsically Unstructured Domain 3 of Hepatitis C Virus NS5A Forms a “Fuzzy Complex” with VAPB-MSP Domain Which Carries ALS-Causing Mutations

(2012) Garvita Gupta et al.   PLoS One

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

(2012) Annalisa Bianco et al.   PLoS Pathogens

Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

(2011) Simon Reiss et al.   Cell Host & Microbe

Hepatitis C Virus NS5A Protein Interacts with Phosphatidylinositol 4-Kinase Type IIIα and Regulates Viral Propagation

(2011) Yun-Sook Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication

(2011) K. L. Berger et al.   JOURNAL OF VIROLOGY

ARFGAP1 promotes AP-2-dependent endocytosis

(2011) Ming Bai et al.   NATURE CELL BIOLOGY

The Role of the Phosphatidylinositol 4-Kinase PI4KA in Hepatitis C Virus-Induced Host Membrane Rearrangement

(2011) Andrew W. Tai et al.   PLoS One

RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses

(2011) D. Panda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

IL28B inhibits hepatitis C virus replication through the JAK–STAT pathway

(2010) Leiliang Zhang et al.   JOURNAL OF HEPATOLOGY

All Three Domains of the Hepatitis C Virus Nonstructural NS5A Protein Contribute to RNA Binding

(2010) T. L. Foster et al.   JOURNAL OF VIROLOGY

Role for ADP Ribosylation Factor 1 in the Regulation of Hepatitis C Virus Replication

(2010) M. Matto et al.   JOURNAL OF VIROLOGY

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

Three Homologous ArfGAPs Participate in Coat Protein I-mediated Transport

(2009) Akina Saitoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of GBF1 as a Cellular Factor Required for Hepatitis C Virus RNA Replication

(2009) L. Goueslain et al.   JOURNAL OF VIROLOGY

Golgicide A reveals essential roles for GBF1 in Golgi assembly and function

(2009) José B Sáenz et al.   Nature Chemical Biology

SAC1 lipid phosphatase and growth control of the secretory pathway

(2008) Anastasia Blagoveshchenskaya et al.   Molecular BioSystems

A role for the host coatomer and KDEL receptor in early vaccinia biogenesis

(2008) L. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

(2008) Nicole Appel et al.   PLoS Pathogens