Glycosyltransferases: mechanisms and applications in natural product development
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Glycosyltransferases: mechanisms and applications in natural product development
Authors
Keywords
-
Journal
CHEMICAL SOCIETY REVIEWS
Volume 44, Issue 22, Pages 8350-8374
Publisher
Royal Society of Chemistry (RSC)
Online
2015-09-02
DOI
10.1039/c5cs00600g
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Synthetic Biology Approaches to Fluorinated Polyketides
- (2015) Benjamin W. Thuronyi et al. ACCOUNTS OF CHEMICAL RESEARCH
- Biosynthesis of the CarbamoylatedD-Gulosamine Moiety of Streptothricins: Involvement of a Guanidino-N-glycosyltransferase and anN-Acetyl-D-gulosamine Deacetylase
- (2015) Zhengyan Guo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2
- (2015) Heng Keat Tam et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Elicitation of secondary metabolism in actinomycetes
- (2015) Usama Ramadan Abdelmohsen et al. BIOTECHNOLOGY ADVANCES
- Atomistic insight into the catalytic mechanism of glycosyltransferases by combined quantum mechanics/molecular mechanics (QM/MM) methods
- (2015) Igor Tvaroška CARBOHYDRATE RESEARCH
- Complete switch from α-2,3- to α-2,6-regioselectivity in Pasteurella dagmatis β-d-galactoside sialyltransferase by active-site redesign
- (2015) Katharina Schmölzer et al. CHEMICAL COMMUNICATIONS
- Highly efficient one-step PCR-based mutagenesis technique for large plasmids using high-fidelity DNA polymerase
- (2015) H. Liu et al. GENETICS AND MOLECULAR RESEARCH
- Structural and Enzymatic Analysis of TarM Glycosyltransferase fromStaphylococcus aureusReveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid
- (2015) Cengiz Koç et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii
- (2015) Longhai Dai et al. PLANT AND CELL PHYSIOLOGY
- De novo production of the plant-derived alkaloid strictosidine in yeast
- (2015) Stephanie Brown et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and mechanism ofStaphylococcus aureusTarM, the wall teichoic acid α-glycosyltransferase
- (2015) Solmaz Sobhanifar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for acceptor-substrate recognition of UDP-glucose: anthocyanidin 3-O-glucosyltransferase fromClitoria ternatea
- (2015) Takeshi Hiromoto et al. PROTEIN SCIENCE
- Identification and Analysis of the Paulomycin Biosynthetic Gene Cluster and Titer Improvement of the Paulomycins in Streptomyces paulus NRRL 8115
- (2015) Jine Li et al. PLoS One
- Structures of Kibdelomycin Bound to Staphylococcus aureus GyrB and ParE Showed a Novel U-Shaped Binding Mode
- (2014) Jun Lu et al. ACS Chemical Biology
- Arixanthomycins A–C: Phylogeny-Guided Discovery of Biologically Active eDNA-Derived Pentangular Polyphenols
- (2014) Hahk-Soo Kang et al. ACS Chemical Biology
- Antibiotic Resistance Mechanisms Inform Discovery: Identification and Characterization of a Novel Amycolatopsis Strain Producing Ristocetin
- (2014) Andrew W. Truman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The astaxanthin dideoxyglycoside biosynthesis pathway in Sphingomonas sp. PB304
- (2014) Se Hyeuk Kim et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Structural Studies of the Spinosyn Forosaminyltransferase, SpnP
- (2014) Eta A. Isiorho et al. BIOCHEMISTRY
- Advances in the biotechnological glycosylation of valuable flavonoids
- (2014) Jianbo Xiao et al. BIOTECHNOLOGY ADVANCES
- Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae
- (2014) Yuriy Rebets et al. BMC GENOMICS
- Identification and functional characterization of a flax UDP-glycosyltransferase glucosylating secoisolariciresinol (SECO) into secoisolariciresinol monoglucoside (SMG) and diglucoside (SDG)
- (2014) Kaushik Ghose et al. BMC PLANT BIOLOGY
- An Iron-Containing Dodecameric Heptosyltransferase Family Modifies Bacterial Autotransporters in Pathogenesis
- (2014) Qiuhe Lu et al. Cell Host & Microbe
- Production of bioactive ginsenoside compound K in metabolically engineered yeast
- (2014) Xing Yan et al. CELL RESEARCH
- Uncovering a Glycosyltransferase Provides Insights into the Glycosylation Step during Macrolactin and Bacillaene Biosynthesis
- (2014) Wen Qin et al. CHEMBIOCHEM
- Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK-68,597 Biosynthetic Cluster
- (2014) Grace Yim et al. CHEMBIOCHEM
- A Simple Strategy for Glycosyltransferase-Catalyzed Aminosugar Nucleotide Synthesis
- (2014) Jianjun Zhang et al. CHEMBIOCHEM
- A two-step O- to C-glycosidic bond rearrangement using complementary glycosyltransferase activities
- (2014) Alexander Gutmann et al. CHEMICAL COMMUNICATIONS
- Highly efficient targeted mutagenesis in axolotl using Cas9 RNA-guided nuclease
- (2014) G. P. Flowers et al. DEVELOPMENT
- Crystal structures of sialyltransferase from Photobacterium damselae
- (2014) Nhung Huynh et al. FEBS LETTERS
- Theoretical study of enzymatic catalysis explains why the trapped covalent intermediate in the E303C mutant of glycosyltransferase GTB was not detected in the wild-type enzyme
- (2014) Adela Bobovská et al. GLYCOBIOLOGY
- Bacterial origin of a diverse family of UDP-glycosyltransferase genes in the Tetranychus urticae genome
- (2014) Seung-Joon Ahn et al. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Identification of a Novel Protein Binding Motif within the T-synthase for the Molecular Chaperone Cosmc
- (2014) Rajindra P. Aryal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structures of Complexes of a Metal-independent Glycosyltransferase GT6 fromBacteroides ovatuswith UDP-N-Acetylgalactosamine (UDP-GalNAc) and Its Hydrolysis Products
- (2014) Tram T. K. Pham et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of a NovelO-LinkedN-Acetyl-d-glucosamine (O-GlcNAc) Transferase, GtfA, Reveals Insights into the Glycosylation of Pneumococcal Serine-rich Repeat Adhesins
- (2014) Wei-Wei Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mining Soil Metagenomes to Better Understand the Evolution of Natural Product Structural Diversity: Pentangular Polyphenols as a Case Study
- (2014) Hahk-Soo Kang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular cloning and characterization of genistein 4′-O-glucoside specific glycosyltransferase from Bacopa monniera
- (2014) Ruby et al. MOLECULAR BIOLOGY REPORTS
- Exploring the Catalytic Promiscuity of a New Glycosyltransferase from Carthamus tinctorius
- (2014) Kebo Xie et al. ORGANIC LETTERS
- Echinostoma caproni(Trematoda): differentialin vivomucin expression and glycosylation in high- and low-compatible hosts
- (2014) A. Cortés et al. PARASITE IMMUNOLOGY
- Comparative analysis of Arabidopsis UGT74 glucosyltransferases reveals a special role of UGT74C1 in glucosinolate biosynthesis
- (2014) C. Douglas Grubb et al. PLANT JOURNAL
- Identification and Characterization of a New Erythromycin Biosynthetic Gene Cluster in Actinopolyspora erythraea YIM90600, a Novel Erythronolide-Producing Halophilic Actinomycete Isolated from Salt Field
- (2014) Dandan Chen et al. PLoS One
- Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16 hydroxylase from Bupleurum falcatum
- (2014) T. Moses et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for the recruitment of glycogen synthase by glycogenin
- (2014) E. Zeqiraj et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plant genome engineering in full bloom
- (2014) Jorge Lozano-Juste et al. TRENDS IN PLANT SCIENCE
- A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family
- (2014) Qing Yao et al. eLife
- Plant glyco-biotechnology on the way to synthetic biology
- (2014) Andreas Loos et al. Frontiers in Plant Science
- The structure of human α-2,6-sialyltransferase reveals the binding mode of complex glycans
- (2013) Bernd Kuhn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structure of starch synthase I from barley: insight into regulatory mechanisms of starch synthase activity
- (2013) Jose A. Cuesta-Seijo et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Leloir Glycosyltransferases and Natural Product Glycosylation: Biocatalytic Synthesis of theC-Glucoside Nothofagin, a Major Antioxidant of Redbush Herbal Tea
- (2013) Linda Bungaruang et al. ADVANCED SYNTHESIS & CATALYSIS
- Arimetamycin A: Improving Clinically Relevant Families of Natural Products through Sequence-Guided Screening of Soil Metagenomes
- (2013) Hahk-Soo Kang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Crystal Structures of Bifunctional Penicillin-Binding Protein 4 from Listeria monocytogenes
- (2013) Jae-Hee Jeong et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Engineered Biosynthesis of Disaccharide-Modified Polyene Macrolides
- (2013) Eimear De Poire et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Tracking Down Biotransformation to the Genetic Level: Identification of a Highly Flexible Glycosyltransferase from Saccharothrix espanaensis
- (2013) Tina Strobel et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Versatility of Enzymes Catalyzing Late Steps in Polyene 67-121C Biosynthesis
- (2013) Niamh STEPHENS et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Functional identification of the gene encoding the enzyme involved in mannosylation in ramoplanin biosynthesis in Actinoplanes sp.
- (2013) Jun-Sheng Chen et al. BIOTECHNOLOGY LETTERS
- Bioactivity-Guided Genome Mining Reveals the Lomaiviticin Biosynthetic Gene Cluster inSalinispora tropica
- (2013) Roland D. Kersten et al. CHEMBIOCHEM
- A Unique Amino Transfer Mechanism for Constructing the β-Amino Fatty Acid Starter Unit in the Biosynthesis of the Macrolactam Antibiotic Cremimycin
- (2013) Keita Amagai et al. CHEMBIOCHEM
- Unconventional Origin and Hybrid System for Construction of Pyrrolopyrrole Moiety in Kosinostatin Biosynthesis
- (2013) Hong-Min Ma et al. CHEMISTRY & BIOLOGY
- A QM/MM Investigation of the Catalytic Mechanism of Metal-Ion-Independent Core 2 β1,6-N-Acetylglucosaminyltransferase
- (2013) Igor Tvaroška et al. CHEMISTRY-A EUROPEAN JOURNAL
- Formation of a Covalent Glycosyl-Enzyme Species in a Retaining Glycosyltransferase
- (2013) Víctor Rojas-Cervellera et al. CHEMISTRY-A EUROPEAN JOURNAL
- New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris
- (2013) Thomas Vogl et al. CURRENT OPINION IN BIOTECHNOLOGY
- C-glycosylation of anhydrotetracycline scaffold with SsfS6 from the SF2575 biosynthetic pathway
- (2013) Li Li et al. JOURNAL OF ANTIBIOTICS
- Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-decarboxylase IdnL3
- (2013) Makoto Takaishi et al. JOURNAL OF ANTIBIOTICS
- Crystal Structures of β-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding
- (2013) Yuko Tsutsui et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enzymatic Basis forN-Glycan Sialylation
- (2013) Lu Meng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Combinatorial biosynthesis and antibacterial evaluation of glycosylated derivatives of 12-membered macrolide antibiotic YC-17
- (2013) Pramod B. Shinde et al. JOURNAL OF BIOTECHNOLOGY
- Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
- (2013) Brian O. Bachmann et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Genetic Insights into Pyralomicin Biosynthesis in Nonomuraea spiralis IMC A-0156
- (2013) Patricia M. Flatt et al. JOURNAL OF NATURAL PRODUCTS
- Crystal structure of UDP-glucose:anthocyanidin 3-O-glucosyltransferase fromClitoria ternatea
- (2013) Takeshi Hiromoto et al. JOURNAL OF SYNCHROTRON RADIATION
- Characterizing Amosamine Biosynthesis in Amicetin Reveals AmiG as a Reversible Retaining Glycosyltransferase
- (2013) Ruidong Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Glycosyltransferase Involved in Thurandacin Biosynthesis Catalyzes Both O- and S-Glycosylation
- (2013) Huan Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Substrate-Assisted and Nucleophilically Assisted Catalysis in Bovine α1,3-Galactosyltransferase. Mechanistic Implications for Retaining Glycosyltransferases
- (2013) Hansel Gómez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cloning, Characterization and Heterologous Expression of the Indolocarbazole Biosynthetic Gene Cluster from Marine-Derived Streptomyces sanyensis FMA
- (2013) Tong Li et al. Marine Drugs
- Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli
- (2013) Ming Jiang et al. METABOLIC ENGINEERING
- Metabolic engineering of Escherichia coli for production of salvianic acid A via an artificial biosynthetic pathway
- (2013) Yuan-Feng Yao et al. METABOLIC ENGINEERING
- Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides
- (2013) Zhubo Dai et al. METABOLIC ENGINEERING
- Enhancement of nystatin production by redirecting precursor fluxes after disruption of the tetramycin gene from Streptomyces ahygroscopicus
- (2013) Jun Ren et al. MICROBIOLOGICAL RESEARCH
- Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics
- (2013) Jeremy R. Lohman et al. Molecular BioSystems
- The biosynthetic gene cluster for sophorolipids: a biotechnological interesting biosurfactant produced byStarmerella bombicola
- (2013) Inge N. A. Van Bogaert et al. MOLECULAR MICROBIOLOGY
- High-level semi-synthetic production of the potent antimalarial artemisinin
- (2013) C. J. Paddon et al. NATURE
- A bacterial toxin catalyzing tyrosine glycosylation of Rho and deamidation of Gq and Gi proteins
- (2013) Thomas Jank et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The carbohydrate-active enzymes database (CAZy) in 2013
- (2013) Vincent Lombard et al. NUCLEIC ACIDS RESEARCH
- Dissecting Glycosylation Steps in Lobophorin Biosynthesis Implies an Iterative Glycosyltransferase
- (2013) Sumei Li et al. ORGANIC LETTERS
- Identification of the Grincamycin Gene Cluster Unveils Divergent Roles for GcnQ in Different Hosts, Tailoring the l-Rhodinose Moiety
- (2013) Yun Zhang et al. ORGANIC LETTERS
- Molecular Characterization of UGT94F2 and UGT86C4, Two Glycosyltransferases from Picrorhiza kurrooa: Comparative Structural Insight and Evaluation of Substrate Recognition
- (2013) Wajid Waheed Bhat et al. PLoS One
- Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis
- (2013) R. W. Gantt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structures of an archaeal oligosaccharyltransferase provide insights into the catalytic cycle of N-linked protein glycosylation
- (2013) S. Matsumoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structure of the Pseudomonas aeruginosa MurG: UDP-GlcNAc Substrate Complex
- (2013) Kieron Brown et al. PROTEIN AND PEPTIDE LETTERS
- Crystal structure of SsfS6, the putativeC-glycosyltransferase involved in SF2575 biosynthesis
- (2013) Fengbin Wang et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Sugar-coated sensor chip and nanoparticle surfaces for the in vitro enzymatic synthesis of starch-like materials
- (2013) Ellis C. O'Neill et al. Chemical Science
- Crystal structure of the C-terminal globular domain of the third paralog of the Archaeoglobus fulgidus oligosaccharyltransferases
- (2013) Shunsuke Matsumoto et al. BMC STRUCTURAL BIOLOGY
- Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis
- (2013) A. Striebeck et al. Open Biology
- A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewisx
- (2012) Go Sugiarto et al. ACS Chemical Biology
- Switching betweenO- andC-Glycosyltransferase through Exchange of Active-Site Motifs
- (2012) Alexander Gutmann et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cooperation of Two Bifunctional Enzymes in the Biosynthesis and Attachment of Deoxysugars of the Antitumor Antibiotic Mithramycin
- (2012) Guojun Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- IgG-Fc glycoengineering in non-mammalian expression hosts
- (2012) Andreas Loos et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG
- (2012) Eta A. Isiorho et al. BIOCHEMISTRY
- Crystal Structure of the C-Terminal Globular Domain of Oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 Å Resolution
- (2012) Shunsuke Matsumoto et al. BIOCHEMISTRY
- Interdomain Disulfide Bridge in the Rice Granule Bound Starch Synthase I Catalytic Domain as Elucidated by X-Ray Structure Analysis
- (2012) Mitsuru MOMMA et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Recent structures, evolution and mechanisms of glycosyltransferases
- (2012) Christelle Breton et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structure of human POFUT2: insights into thrombospondin type 1 repeat fold andO-fucosylation
- (2012) Chun-I Chen et al. EMBO JOURNAL
- The structure ofClostridium difficiletoxin A glucosyltransferase domain bound to Mn2+and UDP provides insights into glucosyltransferase activity and product release
- (2012) Nunzia D’Urzo et al. FEBS Journal
- Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin inStreptomyces nogalater
- (2012) Magnus Claesson et al. FEBS Journal
- Glycosyltransferase complexes improve glycolipid synthesis
- (2012) Waldo Spessott et al. FEBS LETTERS
- Structure-based phylogeny of polyene macrolide antibiotic glycosyltransferases
- (2012) Yanhua Sun et al. GENE
- Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan
- (2012) Robert W. Wheatley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tight Complex Formation between Cosmc Chaperone and Its Specific Client Non-native T-synthase Leads to Enzyme Activity and Client-driven Dissociation
- (2012) Rajindra P. Aryal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glycosyltransferases from Oat (Avena) Implicated in the Acylation of Avenacins
- (2012) Amorn Owatworakit et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Determinants ofClostridium difficileToxin A Glucosyltransferase Activity
- (2012) Rory N. Pruitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Mithramycin Analogue with High Antitumor Activity and Less Toxicity Generated by Combinatorial Biosynthesis
- (2012) Luz E. Núñez et al. JOURNAL OF MEDICINAL CHEMISTRY
- Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
- (2012) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Substrate-Assisted Catalytic Mechanism of O-GlcNAc Transferase Discovered by Quantum Mechanics/Molecular Mechanics Investigation
- (2012) Igor Tvaroška et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Retaining Glycosyltransferase Mechanism Studied by QM/MM Methods: Lipopolysaccharyl-α-1,4-galactosyltransferase C Transfers α-Galactose via an Oxocarbenium Ion-like Transition State
- (2012) Hansel Gómez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A structural motif is the recognition site for a new family of bacterial protein O-glycosyltransferases
- (2012) Marie-Ève Charbonneau et al. MOLECULAR MICROBIOLOGY
- Crystallographic snapshot of cellulose synthesis and membrane translocation
- (2012) Jacob L. W. Morgan et al. NATURE
- O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis
- (2012) Marianne Schimpl et al. Nature Chemical Biology
- Natural Product Disaccharide Engineering through Tandem Glycosyltransferase Catalysis Reversibility and Neoglycosylation
- (2012) Pauline Peltier-Pain et al. ORGANIC LETTERS
- The Sg-1 Glycosyltransferase Locus Regulates Structural Diversity of Triterpenoid Saponins of Soybean
- (2012) T. Sayama et al. PLANT CELL
- UDP-Glycosyltransferases from the UGT73C Subfamily in Barbarea vulgaris Catalyze Sapogenin 3-O-Glucosylation in Saponin-Mediated Insect Resistance
- (2012) J. M. Augustin et al. PLANT PHYSIOLOGY
- Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex
- (2012) Michael C. Cavalier et al. PLoS One
- Structural and mechanistic analysis of the membrane-embedded glycosyltransferase WaaA required for lipopolysaccharide synthesis
- (2012) H. Schmidt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystallographic and NMR Evidence for Flexibility in Oligosaccharyltransferases and Its Catalytic Significance
- (2012) James Nyirenda et al. STRUCTURE
- Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen
- (2012) Nethaji Thiyagarajan et al. Scientific Reports
- The Molecular Mechanism of Enzymatic Glycosyl Transfer with Retention of Configuration: Evidence for a Short-Lived Oxocarbenium-Like Species
- (2011) Albert Ardèvol et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities
- (2011) Ah Reum Han et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Glycosylation of various flavonoids by recombinant oleandomycin glycosyltransferase from Streptomyces antibioticus in batch and repeated batch modes
- (2011) Sung Hee Choi et al. BIOTECHNOLOGY LETTERS
- Specific Enzyme Complex of β-1,4-Galactosyltransferase-II and Glucuronyltransferase-P Facilitates Biosynthesis ofN-linked Human Natural Killer-1 (HNK-1) Carbohydrate
- (2011) Tetsuya Kouno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Insights into the Glycosyltransferase Activity of theActinobacillus pleuropneumoniaeHMW1C-like Protein
- (2011) Fumihiro Kawai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional Organization of GolgiN- andO-Glycosylation Pathways Involves pH-dependent Complex Formation That Is Impaired in Cancer Cells
- (2011) Antti Hassinen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure and Mechanism of the Lipooligosaccharide Sialyltransferase fromNeisseria meningitidis
- (2011) Leo Y.-C. Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Iridoid-specific Glucosyltransferase fromGardenia jasminoides
- (2011) Mai Nagatoshi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Molecular Chaperone Mediates a Two-protein Enzyme Complex and Glycosylation of Serine-rich Streptococcal Adhesins
- (2011) Ren Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of the Glycosyltransferase EryCIII in Complex with its Activating P450 Homologue EryCII
- (2011) Martin C. Moncrieffe et al. JOURNAL OF MOLECULAR BIOLOGY
- X-ray structure of a bacterial oligosaccharyltransferase
- (2011) Christian Lizak et al. NATURE
- Principles of activation and permeation in an anion-selective Cys-loop receptor
- (2011) Ryan E. Hibbs et al. NATURE
- Structure of human O-GlcNAc transferase and its complex with a peptide substrate
- (2011) Michael B. Lazarus et al. NATURE
- Sublancin is not a lantibiotic but an S-linked glycopeptide
- (2011) Trent J Oman et al. Nature Chemical Biology
- Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase
- (2011) Seung Seo Lee et al. Nature Chemical Biology
- Asymmetric Enzymatic Glycosylation of Mitoxantrone
- (2011) Maoquan Zhou et al. ORGANIC LETTERS
- An evolutionary view of functional diversity in family 1 glycosyltransferases
- (2011) Keiko Yonekura-Sakakibara et al. PLANT JOURNAL
- A genome-wide phylogenetic reconstruction of family 1 UDP-glycosyltransferases revealed the expansion of the family during the adaptation of plants to life on land
- (2011) Lorenzo Caputi et al. PLANT JOURNAL
- Structural Insights into the Mechanism of Protein O-Fucosylation
- (2011) Erandi Lira-Navarrete et al. PLoS One
- Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity
- (2011) A. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biosynthesis of the apoptolidins in Nocardiopsis sp. FU 40
- (2011) Yu Du et al. TETRAHEDRON
- Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors
- (2010) James C. Errey et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Glycosylation Steps during Spiramycin Biosynthesis in Streptomyces ambofaciens: Involvement of Three Glycosyltransferases and Their Interplay with Two Auxiliary Proteins
- (2010) H. C. Nguyen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Formation and Attachment of the Deoxysugar Moiety and Assembly of the Gene Cluster for Caprazamycin Biosynthesis
- (2010) L. Kaysser et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Engineered Biosynthesis of Gilvocarcin Analogues with Altered Deoxyhexopyranose Moieties
- (2010) Micah D. Shepherd et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- TDP-L-Megosamine Biosynthesis Pathway Elucidation and Megalomicin A Production in Escherichia coli
- (2010) M. Useglio et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Cloning and Characterization of the Ravidomycin and Chrysomycin Biosynthetic Gene Clusters
- (2010) Madan K. Kharel et al. CHEMBIOCHEM
- Analysis of the Sorangicin Gene Cluster Reinforces the Utility of a Combined Phylogenetic/Retrobiosynthetic Analysis for Deciphering Natural Product Assembly by trans-AT PKS
- (2010) Herbert Irschik et al. CHEMBIOCHEM
- Trapping and characterization of covalent intermediates of mutant retaining glycosyltransferases
- (2010) Naoto Soya et al. GLYCOBIOLOGY
- Cloning of the biosynthetic gene cluster for naphthoxanthene antibiotic FD-594 from Streptomyces sp. TA-0256
- (2010) Fumitaka Kudo et al. JOURNAL OF ANTIBIOTICS
- A Biosynthetic Pathway for BE-7585A, a 2-Thiosugar-Containing Angucycline-Type Natural Product
- (2010) Eita Sasaki et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases
- (2010) Guangyu Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Characterization of Tiacumicin B Biosynthetic Gene Cluster Affording Diversified Tiacumicin Analogues and Revealing a Tailoring Dihalogenase
- (2010) Yi Xiao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Exploring genomes for glycosyltransferases
- (2010) Sara Fasmer Hansen et al. Molecular BioSystems
- Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099
- (2010) Ying Ding et al. Molecular BioSystems
- Genomic and Coexpression Analyses Predict Multiple Genes Involved in Triterpene Saponin Biosynthesis in Medicago truncatula
- (2010) M. A. Naoumkina et al. PLANT CELL
- Functional Differentiation of the Glycosyltransferases That Contribute to the Chemical Diversity of Bioactive Flavonol Glycosides in Grapevines (Vitis vinifera)
- (2010) E. Ono et al. PLANT CELL
- Structural basis for glucose-6-phosphate activation of glycogen synthase
- (2010) Sulochanadevi Baskaran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of the ‘pristinamycin supercluster’ of Streptomyces pristinaespiralis
- (2010) Yvonne Mast et al. Microbial Biotechnology
- Molecular mechanism of elongation factor 1A inhibition by aLegionella pneumophilaglycosyltransferase
- (2009) Ramon Hurtado-Guerrero et al. BIOCHEMICAL JOURNAL
- NMR Spectroscopic Characterization of the Sialyltransferase CstII fromCampylobacter jejuni: Histidine 188 Is the General Base
- (2009) Patrick H. W. Chan et al. BIOCHEMISTRY
- Comprehensive analysis of glycosyltransferases in eukaryotic genomes for structural and functional characterization of glycans
- (2009) Kosuke Hashimoto et al. CARBOHYDRATE RESEARCH
- Cloning and Sequencing of the Biosynthetic Gene Cluster for Saquayamycin Z and Galtamycin B and the Elucidation of the Assembly of Their Saccharide Chains
- (2009) Annette Erb et al. CHEMBIOCHEM
- Chimeric Glycosyltransferases for the Generation of Hybrid Glycopeptides
- (2009) Andrew W. Truman et al. CHEMISTRY & BIOLOGY
- Engineering a Function into a Glycosyltransferase
- (2009) Christine Krauth et al. CHEMISTRY & BIOLOGY
- Single amino acid mutations ofMedicagoglycosyltransferase UGT85H2 enhance activity and impart reversibility
- (2009) Luzia V. Modolo et al. FEBS LETTERS
- Hetero-oligomeric interactions between early glycosyltransferases of the dolichol cycle
- (2009) C. Noffz et al. GLYCOBIOLOGY
- Modulation of Deoxysugar Transfer by the Elloramycin Glycosyltransferase ElmGT through Site-Directed Mutagenesis
- (2009) A. Ramos et al. JOURNAL OF BACTERIOLOGY
- Crystal Structures of Glycosyltransferase UGT78G1 Reveal the Molecular Basis for Glycosylation and Deglycosylation of (Iso)flavonoids
- (2009) Luzia V. Modolo et al. JOURNAL OF MOLECULAR BIOLOGY
- Hybrid Quantum Mechanical/Molecular Mechanical Investigation of the β-1,4-Galactosyltransferase-I Mechanism
- (2009) Martin Krupička et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Structural insight into mammalian sialyltransferases
- (2009) Francesco V Rao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Local Differentiation of Sugar Donor Specificity of Flavonoid Glycosyltransferase in Lamiales
- (2009) A. Noguchi et al. PLANT CELL
- Probing the Aglycon Promiscuity of an Engineered Glycosyltransferase
- (2008) Richard W. Gantt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The in vitro Characterization of Polyene Glycosyltransferases AmphDI and NysDI
- (2008) Changsheng Zhang et al. CHEMBIOCHEM
- Glycosylated Derivatives of Steffimycin: Insights into the Role of the Sugar Moieties for the Biological Activity
- (2008) Carlos Olano et al. CHEMBIOCHEM
- Optimizing Glycosyltransferase Specificity via “Hot Spot” Saturation Mutagenesis Presents a Catalyst for Novobiocin Glycorandomization
- (2008) Gavin J. Williams et al. CHEMISTRY & BIOLOGY
- Biochemical and Structural Insights of the Early Glycosylation Steps in Calicheamicin Biosynthesis
- (2008) Changsheng Zhang et al. CHEMISTRY & BIOLOGY
- Structural insights into mechanism and specificity of O-GlcNAc transferase
- (2008) Andrew J Clarke et al. EMBO JOURNAL
- The yeast oligosaccharyltransferase complex can be replaced by STT3 from Leishmania major
- (2008) K. Hese et al. GLYCOBIOLOGY
- A Kinetic Analysis of Regiospecific Glucosylation by Two Glycosyltransferases ofArabidopsis thaliana
- (2008) Adam M. Cartwright et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational Changes and Reaction of Clostridial Glycosylating Toxins
- (2008) Mathias O.P. Ziegler et al. JOURNAL OF MOLECULAR BIOLOGY
- Mithramycin Analogues Generated by Combinatorial Biosynthesis Show Improved Bioactivity
- (2008) Irfan Baig et al. JOURNAL OF NATURAL PRODUCTS
- Crystal structure of trioxacarcin A covalently bound to DNA
- (2008) R. Pfoh et al. NUCLEIC ACIDS RESEARCH
- Engineered biosynthesis of hybrid macrolide polyketides containing d-angolosamine and d-mycaminose moieties
- (2008) Ursula Schell et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
- Glycosyltransferases: Structures, Functions, and Mechanisms
- (2007) L.L. Lairson et al. Annual Review of Biochemistry
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started