Engineered Biosynthesis of Disaccharide-Modified Polyene Macrolides

Versatility of Enzymes Catalyzing Late Steps in Polyene 67-121C Biosynthesis

(2013) Niamh STEPHENS et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Biosynthesis and pathway engineering of antifungal polyene macrolides in actinomycetes

(2013) Dekun Kong et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

C2′-OH of Amphotericin B Plays an Important Role in Binding the Primary Sterol of Human Cells but Not Yeast Cells

(2013) Brandon C. Wilcock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica

(2012) Mi-Jin Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Streptomyces nodosusHost Strains Optimized for Polyene Glycosylation Engineering

(2012) Niamh STEPHENS et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Structure-based phylogeny of polyene macrolide antibiotic glycosyltransferases

(2012) Yanhua Sun et al.   GENE

In vivo investigation of the substrate recognition capability and activity affecting amino acid residues of glycosyltransferase FscMI in the biosynthesis of candicidin

(2012) Xuan Lei et al.   Molecular BioSystems

Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation

(2011) Aram Chang et al.   CURRENT OPINION IN BIOTECHNOLOGY

A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus

(2010) Jörg Barke et al.   BMC BIOLOGY

Redesign of Polyene Macrolide Glycosylation: Engineered Biosynthesis of 19-(O)-Perosaminyl- Amphoteronolide B

(2010) Eve Hutchinson et al.   CHEMISTRY & BIOLOGY

Synthesis and biological evaluation of amphotericin B derivatives

(2010) Astrid A. Volmer et al.   NATURAL PRODUCT REPORTS

Incomplete β-Ketone Processing as a Mechanism for Polyene Structural Variation in the FR-008/Candicidin Complex

(2008) Yongjun Zhou et al.   CHEMISTRY & BIOLOGY

Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei

(2008) Trygve Brautaset et al.   CHEMISTRY & BIOLOGY

Engineered Synthesis of 7-Oxo- and 15-Deoxy-15-Oxo-Amphotericins: Insights into Structure-Activity Relationships in Polyene Antibiotics

(2008) Patrick Power et al.   CHEMISTRY & BIOLOGY

Coordination of export and glycosylation of landomycins inStreptomyces cyanogenusS136

(2008) Iryna Ostash et al.   FEMS MICROBIOLOGY LETTERS