Activation of multiple Eph receptors on neuronal membranes correlates with the onset of optic neuropathy

Solving neurodegeneration: common mechanisms and strategies for new treatments

(2022) Lauren K. Wareham et al.   Molecular Neurodegeneration

Engineering a 3D hydrogel system to study optic nerve head astrocyte morphology and behavior

(2022) Ana N. Strat et al.   EXPERIMENTAL EYE RESEARCH

Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system

(2022) Noemie Vilallongue et al.   Nature Communications

Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction

(2021) Ana Belen Lopez‐Rodriguez et al.   Alzheimers & Dementia

Longitudinal Morphological and Functional Assessment of RGC Neurodegeneration After Optic Nerve Crush in Mouse

(2020) Liang Li et al.   Frontiers in Cellular Neuroscience

Optic neuropathy: A 15-year retrospective observational study

(2020) José Miguel Alves et al.   Multiple Sclerosis and Related Disorders

EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke

(2019) Anne-Sophie Ernst et al.   Acta Neuropathologica Communications

Role of forward and reverse signaling in Eph receptor and ephrin mediated cell segregation

(2019) Zhonglin Wu et al.   EXPERIMENTAL CELL RESEARCH

EphB3 signaling induces cortical endothelial cell death and disrupts the blood–brain barrier after traumatic brain injury

(2018) Poincyane Assis-Nascimento et al.   Cell Death & Disease

EphrinB/EphB forward signaling in Müller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model

(2018) Shu-Ting Liu et al.   Acta Neuropathologica Communications

Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma

(2017) Pete A. Williams et al.   Frontiers in Neuroscience

Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury

(2016) Angeliki M. Nikolakopoulou et al.   ASN Neuro

Virally delivered, constitutively active NFκB improves survival of injured retinal ganglion cells

(2016) Galina Dvoriantchikova et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mechanisms of ephrin–Eph signalling in development, physiology and disease

(2016) Artur Kania et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

EphB3 signaling propagates synaptic dysfunction in the traumatic injured brain

(2016) Enmanuel J. Perez et al.   NEUROBIOLOGY OF DISEASE

Changes in ganglion cells during retinal degeneration

(2016) Susmita Saha et al.   NEUROSCIENCE

Identification of approved drugs that inhibit the binding of amyloid β oligomers to ephrin type-B receptor 2

(2016) Koichiro Suzuki et al.   FEBS Open Bio

Aqueous humor phospholipids of DBA/2J and DBA/2J-Gpnmb+/SjJ mice

(2015) Haiyan Wang et al.   BIOCHIMIE

GluA2 Trafficking Is Involved in Apoptosis of Retinal Ganglion Cells Induced by Activation of EphB/EphrinB Reverse Signaling in a Rat Chronic Ocular Hypertension Model

(2015) L.-D. Dong et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Ephrin-B3 recruits PSD-95 to synapses

(2015) Erkang Fei et al.   NATURE NEUROSCIENCE

Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3

(2015) Martin Hruska et al.   NATURE NEUROSCIENCE

UniPR129 is a competitive small molecule Eph-ephrin antagonist blockingin vitroangiogenesis at low micromolar concentrations

(2014) I Hassan-Mohamed et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Ephrin receptor EphA4 restricts axonal sprouting and enhances branching in the injured mouse optic nerve

(2014) Sandrine Joly et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Current concepts in the diagnosis, pathogenesis and management of nonarteritic anterior ischaemic optic neuropathy

(2014) N R Miller et al.   EYE

EphA4 Activation of c-Abl Mediates Synaptic Loss and LTP Blockade Caused by Amyloid-β Oligomers

(2014) Lina M. Vargas et al.   PLoS One

Abundant Expression of Guidance and Synaptogenic Molecules in the Injured Spinal Cord

(2014) Anne Jacobi et al.   PLoS One

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

(2014) Amy K. Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different roles of axon guidance cues and patterned spontaneous activity in establishing receptive fields in the mouse superior colliculus

(2014) Mingna Liu et al.   Frontiers in Neural Circuits

Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke

(2013) Robin Lemmens et al.   HUMAN MOLECULAR GENETICS

A proteomics view of the molecular mechanisms and biomarkers of glaucomatous neurodegeneration

(2013) Gülgün Tezel   PROGRESS IN RETINAL AND EYE RESEARCH

Regulation of ephrin-A expression in compressed retinocollicular maps

(2012) Tizeta Tadesse et al.   Developmental Neurobiology

EphA Signaling Promotes Actin-based Dendritic Spine Remodeling through Slingshot Phosphatase

(2012) Lei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression and Activation of EphA4 in the Human Brain After Traumatic Injury

(2012) Tony Frugier et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Eph receptors at synapses: Implications in neurodegenerative diseases

(2011) Yu Chen et al.   CELLULAR SIGNALLING

Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection

(2011) George Chenaux et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Eph receptors and ephrins in neuron-astrocyte communication at synapses

(2011) Keith K. Murai et al.   GLIA

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

The three new pathways leading to Alzheimer's disease

(2011) K. Morgan   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

EphA4 Blockers Promote Axonal Regeneration and Functional Recovery Following Spinal Cord Injury in Mice

(2011) Yona Goldshmit et al.   PLoS One

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis

(2010) Georg Martiny-Baron et al.   ANGIOGENESIS

Architecture of Eph receptor clusters

(2010) J. P. Himanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visual Map Development: Bidirectional Signaling, Bifunctional Guidance Molecules, and Competition

(2010) D. A. Feldheim et al.   Cold Spring Harbor Perspectives in Biology

Network analysis of human glaucomatous optic nerve head astrocytes

(2009) Tatiana Nikolskaya et al.   BMC Medical Genomics

Synaptic activity prompts γ-secretase–mediated cleavage of EphA4 and dendritic spine formation

(2009) Eiji Inoue et al.   JOURNAL OF CELL BIOLOGY

Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport

(2009) M. A. Carmona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The molecular phylogeny of eph receptors and ephrin ligands

(2008) Dan O Mellott et al.   BMC CELL BIOLOGY

Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors

(2008) Thomas J Lukas et al.   GENOME BIOLOGY