EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke

EphrinB2 activation enhances angiogenesis, reduces amyloid-β deposits and secondary damage in thalamus at the early stage after cortical infarction in hypertensive rats

(2018) Shihui Xing et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus

(2018) Jordan Koeppen et al.   JOURNAL OF NEUROSCIENCE

Targeting NMDA receptors in stroke: new hope in neuroprotection

(2018) Qiu Jing Wu et al.   Molecular Brain

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

(2017) Kenji Hanamura et al.   PLOS BIOLOGY

Synaptic Activity Protects Neurons Against Calcium-Mediated Oxidation and Contraction of Mitochondria During Excitotoxicity

(2017) Constanze Depp et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke

(2016) Philipp Barteczek et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mechanisms of ephrin–Eph signalling in development, physiology and disease

(2016) Artur Kania et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner

(2016) Lexiao Li et al.   NEUROBIOLOGY OF DISEASE

Variants of Rab GTPase–Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke

(2016) Jennifer L. Lucitti et al.   STROKE

The Cellular Mechanisms of Neuronal Swelling Underlying Cytotoxic Edema

(2015) Ravi L. Rungta et al.   CELL

Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs

(2015) Shotaro Michinaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular pathophysiology of cerebral edema

(2015) Jesse A Stokum et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

Inhibition of HIF prolyl-4-hydroxylases by FG-4497 Reduces Brain Tissue Injury and Edema Formation during Ischemic Stroke

(2014) Stefan Reischl et al.   PLoS One

EphrinB-mediated reverse signalling controls junctional integrity and pro-inflammatory differentiation of endothelial cells

(2014) Hui Liu et al.   THROMBOSIS AND HAEMOSTASIS

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Tight Junction in Blood-Brain Barrier: An Overview of Structure, Regulation, and Regulator Substances

(2012) Wei-Ye Liu et al.   CNS Neuroscience & Therapeutics

Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia

(2012) Reiner Kunze et al.   STROKE

Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia

(2011) Thorsten R. Doeppner et al.   ACTA NEUROPATHOLOGICA

Ephrinb1 and Ephrinb2 Are Associated with Interleukin-7 Receptor α and Retard Its Internalization from the Cell Surface

(2011) Hongyu Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EphB Controls NMDA Receptor Function and Synaptic Targeting in a Subunit-Specific Manner

(2011) M. J. Nolt et al.   JOURNAL OF NEUROSCIENCE

A Signaling Cascade of Nuclear Calcium-CREB-ATF3 Activated by Synaptic NMDA Receptors Defines a Gene Repression Module That Protects against Extrasynaptic NMDA Receptor-Induced Neuronal Cell Death and Ischemic Brain Damage

(2011) S.-J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Endothelial Cell EphrinB2-Dependent Activation of Monocytes in Arteriosclerosis

(2010) Jennifer Braun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Calcium-dependent mitochondrial function and dysfunction in neurons

(2010) Natalia B. Pivovarova et al.   FEBS Journal

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

(2009) Giles E. Hardingham   BIOCHEMICAL SOCIETY TRANSACTIONS

Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity

(2009) R. I. Stanika et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment

(2008) T. Korff et al.   BLOOD

Blockade of EphB2 enhances neurogenesis in the subventricular zone and improves neurological function after cerebral cortical infarction in hypertensive rats

(2008) Shihui Xing et al.   BRAIN RESEARCH

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

Expression and function of ephrin-B1 and its cognate receptor EphB2 in human atherosclerosis: from an aspect of chemotaxis

(2008) Aiji Sakamoto et al.   CLINICAL SCIENCE

Blood Brain Barrier in Hypoxic-Ischemic Conditions

(2008) C. Kaur et al.   CURRENT NEUROVASCULAR RESEARCH

Elevated Synaptic Activity Preconditions Neurons against anin VitroModel of Ischemia

(2008) Joseph S. Tauskela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes

(2008) D. Pfaff et al.   JOURNAL OF CELL SCIENCE

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE