Identification of approved drugs that inhibit the binding of amyloid β oligomers to ephrin type-B receptor 2

Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer's Disease

(2017) Ana María Simón et al.   JOURNAL OF ALZHEIMERS DISEASE

Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay

(2015) Emmanuel Risse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma

(2015) Mehdi Farshchian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dextran sulfate sodium inhibits amyloid-β oligomer binding to cellular prion protein

(2015) Takahiro Aimi et al.   JOURNAL OF NEUROCHEMISTRY

Stimulation of EphB2 attenuates tau phosphorylation through PI3K/Akt-mediated inactivation of glycogen synthase kinase-3β

(2015) Jun Jiang et al.   Scientific Reports

Montelukast targeting the cysteinyl leukotriene receptor 1 ameliorates Aβ1-42-induced memory impairment and neuroinflammatory and apoptotic responses in mice

(2014) Jin'e Lai et al.   NEUROPHARMACOLOGY

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

(2014) Amy K. Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease

(2013) Tae-In Kam et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective effects of EphB2 on Aβ1–42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons

(2013) Dandan Geng et al.   NEUROCHEMISTRY INTERNATIONAL

Reduction and the intracellular translocation of EphB2 in Tg2576 mice and the effects of β-amyloid

(2013) M. Qu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Human LilrB2 Is a  -Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model

(2013) T. Kim et al.   SCIENCE

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase

(2012) S D Wang et al.   ONCOGENE

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

EphBs: an integral link between synaptic function and synaptopathies

(2012) Sean I. Sheffler-Collins et al.   TRENDS IN NEUROSCIENCES

Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death

(2011) W. Kudo et al.   HUMAN MOLECULAR GENETICS

Drug discovery and development focusing on existing medicines: drug re-profiling strategy

(2011) T. Mizushima   JOURNAL OF BIOCHEMISTRY

Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation

(2011) Carmine Giorgio et al.   PLoS One

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

Transfer of bromocriptine across the blood-brain barrier in man

(2010) MOGENS LAUE FRIIS et al.   ACTA NEUROLOGICA SCANDINAVICA

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE