Engineering a 3D hydrogel system to study optic nerve head astrocyte morphology and behavior

Glaucoma in Adults—Screening, Diagnosis, and Management

(2021) Joshua D. Stein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma

(2021) Elizabeth Kimball et al.   PLoS One

A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling

(2021) Haiyan Li et al.   EXPERIMENTAL EYE RESEARCH

Matrix stiffness changes affect astrocyte phenotype in an in vitro injury model

(2021) Yan Hu et al.   NPG Asia Materials

Dynamic self-reinforcement of gene expression determines acquisition of cellular mechanical memory

(2021) Christopher C. Price et al.   BIOPHYSICAL JOURNAL

Mechanosensitive channel inhibition attenuates TGFβ2-induced actin cytoskeletal remodeling and reactivity in mouse optic nerve head astrocytes

(2021) Alexander Kirschner et al.   EXPERIMENTAL EYE RESEARCH

Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress

(2020) Melissa L. Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pleural Effusion Aspirate for Use in 3D Lung Cancer Modeling and Chemotherapy Screening

(2019) Andrea Mazzocchi et al.   ACS Biomaterials-Science & Engineering

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte remodeling without gliosis precedes optic nerve axonopathy

(2018) Melissa L. Cooper et al.   Acta Neuropathologica Communications

Statins reduce TGF-beta2-modulation of the extracellular matrix in cultured astrocytes of the human optic nerve head

(2017) Mi-Lyang Kim et al.   EXPERIMENTAL EYE RESEARCH

Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries

(2017) Daniel Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting Transforming Growth Factor-β Signaling in Primary Open-Angle Glaucoma

(2017) Jenny Wang et al.   JOURNAL OF GLAUCOMA

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Role of astrocyte-synapse interactions in CNS disorders

(2016) Elena Blanco-Suárez et al.   JOURNAL OF PHYSIOLOGY-LONDON

Application of UVA-riboflavin crosslinking to enhance the mechanical properties of extracellular matrix derived hydrogels

(2016) Mark Ahearne et al.   Journal of the Mechanical Behavior of Biomedical Materials

A practical guide to hydrogels for cell culture

(2016) Steven R Caliari et al.   NATURE METHODS

Glia–neuron interactions in the mammalian retina

(2016) Elena Vecino et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Social and novel contexts modify hippocampal CA2 representations of space

(2016) Georgia M. Alexander et al.   Nature Communications

Astrocyte Structural and Molecular Response to Elevated Intraocular Pressure Occurs Rapidly and Precedes Axonal Tubulin Rearrangement within the Optic Nerve Head in a Rat Model

(2016) Shandiz Tehrani et al.   PLoS One

Human astrocytes develop physiological morphology and remain quiescent in a novel 3D matrix

(2015) Amanda L. Placone et al.   BIOMATERIALS

Isolation of intact astrocytes from the optic nerve head of adult mice

(2015) Hee Joo Choi et al.   EXPERIMENTAL EYE RESEARCH

Scleral cross-linking by riboflavin and blue light application in young rabbits: damage threshold and eye growth inhibition

(2015) Hans Peter Iseli et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Mechanical properties of gray and white matter brain tissue by indentation

(2015) Silvia Budday et al.   Journal of the Mechanical Behavior of Biomedical Materials

Riboflavin-induced photo-crosslinking of collagen hydrogel and its application in meniscus tissue engineering

(2015) Jiseung Heo et al.   Drug Delivery and Translational Research

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

(2015) Su-Jin Heo et al.   Scientific Reports

Mechanisms of astrocyte development and their contributions to neurodevelopmental disorders

(2014) Steven A Sloan et al.   CURRENT OPINION IN NEUROBIOLOGY

The Pathophysiology and Treatment of Glaucoma

(2014) Robert N. Weinreb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

Osteopontin Is Induced by TGF-β2 and Regulates Metabolic Cell Activity in Cultured Human Optic Nerve Head Astrocytes

(2014) Carolin Neumann et al.   PLoS One

The role of transforming growth factor β in glaucoma and the therapeutic implications

(2013) Mark A Prendes et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Lamina cribrosa thickening in early glaucoma predicted by a microstructure motivated growth and remodeling approach

(2011) Rafael Grytz et al.   MECHANICS OF MATERIALS

Pathophysiology of human glaucomatous optic nerve damage: Insights from rodent models of glaucoma

(2010) John C. Morrison et al.   EXPERIMENTAL EYE RESEARCH

Glaucomatous cupping of the lamina cribrosa: A review of the evidence for active progressive remodeling as a mechanism

(2010) J. Crawford Downs et al.   EXPERIMENTAL EYE RESEARCH

The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse

(2009) Daniel Sun et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols