Seneca Valley Virus Degrades STING via PERK and ATF6-Mediated Reticulophagy

Spring Viremia of Carp Virus N Protein Negatively Regulates IFN Induction through Autophagy-Lysosome–Dependent Degradation of STING

(2023) Xue-li Wang et al.   JOURNAL OF IMMUNOLOGY

Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release

(2023) Huisheng Liu et al.   PLoS Pathogens

N protein of PEDV plays chess game with host proteins by selective autophagy

(2023) Xueying Zhai et al.   Autophagy

African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation

(2023) Mingyang Cheng et al.   JOURNAL OF VIROLOGY

Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication

(2023) Feifei Diao et al.   PLoS Pathogens

Autophagy is induced by swine acute diarrhea syndrome coronavirus through the cellular IRE1-JNK-Beclin 1 signaling pathway after an interaction of viral membrane-associated papain-like protease and GRP78

(2023) Da Shi et al.   PLoS Pathogens

Role of the cGAS/STING pathway in the control of Brucella abortus infection acquired through the respiratory route

(2023) Iván M. Alonso Paiva et al.   Frontiers in Immunology

Autophagy up-regulation upon FeHV-1 infection on permissive cells

(2023) Gianmarco Ferrara et al.   Frontiers in Veterinary Science

Modifications of the PI3K/Akt/mTOR axis during FeHV-1 infection in permissive cells

(2023) Gianmarco Ferrara et al.   Frontiers in Veterinary Science

African swine fever virus protein p17 promotes mitophagy by facilitating the interaction of SQSTM1 with TOMM70

(2023) Boli Hu et al.   Virulence

Bat STING drives IFN-beta production in anti-RNA virus innate immune response

(2023) Feiyu Fu et al.   Frontiers in Microbiology

SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

(2022) Christopher J. Neufeldt et al.   Communications Biology

The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1

(2022) Maowen Sun et al.   JOURNAL OF VIROLOGY

Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

(2022) Fei Wang et al.   MOLECULAR CELL

The canonical Wnt/β-catenin signaling pathway facilitates pseudorabies virus proliferation and enhances virus-induced autophagy

(2022) Chongyang Wang et al.   VETERINARY MICROBIOLOGY

Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C

(2022) Jianli Tang et al.   mBio

DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS‐STING‐triggered innate immune activation

(2022) Meng Lou et al.   JOURNAL OF MEDICAL VIROLOGY

The Porcine Cyclic GMP-AMP Synthase-STING Pathway Exerts an Unusual Antiviral Function Independent of Interferon and Autophagy

(2022) Sen Jiang et al.   JOURNAL OF VIROLOGY

Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses

(2022) Wenkai Zhou et al.   Science Signaling

Cellular functions of cGAS-STING signaling

(2022) Chen Chen et al.   TRENDS IN CELL BIOLOGY

African Swine Fever Virus MGF-505-7R Negatively Regulates cGAS–STING-Mediated Signaling Pathway

(2021) Dan Li et al.   JOURNAL OF IMMUNOLOGY

Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3

(2021) Wei Wen et al.   Autophagy

STING1 is essential for an RNA-virus triggered autophagy

(2021) Rui Zhang et al.   Autophagy

ER-Phagy: A New Regulator of ER Homeostasis

(2021) Ming Yang et al.   Frontiers in Cell and Developmental Biology

STING signaling activation inhibits HBV replication and attenuates the severity of liver injury and HBV-induced fibrosis

(2021) Yuqi Li et al.   Cellular & Molecular Immunology

Synergetic Contributions of Viral VP1, VP3, and 3C to Activation of the AKT-AMPK-MAPK-MTOR Signaling Pathway for Seneca Valley Virus-Induced Autophagy

(2021) Jiangwei Song et al.   JOURNAL OF VIROLOGY

Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles

(2020) Ren-Qi Yao et al.   Autophagy

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response

(2020) Dongshan Wan et al.   Frontiers in Immunology

HFE inhibits type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation

(2020) Juan Liu et al.   Autophagy

Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis

(2020) Quangang Chen et al.   Scientific Reports

Autophagy is induced and supports virus replication in Enterovirus A71-infected human primary neuronal cells

(2020) Jhao-Yin Lin et al.   Scientific Reports

MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway

(2020) Mingfu Tian et al.   Cell Reports

Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

(2020) L. G. Webb et al.   PLoS Pathogens

A 5-Year Review of Senecavirus A in China since Its Emergence in 2015

(2020) Fuxiao Liu et al.   Frontiers in Veterinary Science

Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies

(2020) Mirko Cortese et al.   Cell Host & Microbe

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

(2020) Steffen Klein et al.   Nature Communications

Porcine epidemic diarrhea virus infections induce autophagy in Vero cells via ROS-dependent endoplasmic reticulum stress through PERK and IRE1 pathways

(2020) Pei Sun et al.   VETERINARY MICROBIOLOGY

cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection

(2019) Qiang Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Experimental Seneca Valley virus infection in market-weight gilts

(2019) Alexandra Buckley et al.   VETERINARY MICROBIOLOGY

Seneca valley virus activates autophagy through the PERK and ATF6 UPR pathways

(2019) Lei Hou et al.   VIROLOGY

STING-dependent translation inhibition restricts RNA virus replication

(2018) Kate M. Franz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudorabies virus induces autophagy to enhance viral replication in mouse neuro-2a cells in vitro

(2018) Changmeng Xu et al.   VIRUS RESEARCH

Dengue virus-induced ER stress is required for autophagy activation, viral replication, and pathogenesis both in vitro and in vivo

(2018) Ying-Ray Lee et al.   Scientific Reports

Enteroviruses Remodel Autophagic Trafficking through Regulation of Host SNARE Proteins to Promote Virus Replication and Cell Exit

(2018) Abigail K. Corona et al.   Cell Reports

Dengue virus and the host innate immune response

(2018) Naoko Uno et al.   Emerging Microbes & Infections

ER homeostasis and autophagy

(2017) Matthew Smith et al.   Essays in Biochemistry

Emergence of novel Seneca Valley virus strains in China, 2017

(2017) Z. Zhu et al.   Transboundary and Emerging Diseases

Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways

(2017) Alessandra Zevini et al.   TRENDS IN IMMUNOLOGY

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

(2017) Sebastian Aguirre et al.   Nature Microbiology

Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression

(2014) Ji Wang et al.   Autophagy

Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection

(2014) Kevin Maringer et al.   CYTOKINE & GROWTH FACTOR REVIEWS

NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING

(2014) Lu Zhang et al.   IMMUNITY

Autophagy—a key player in cellular and body metabolism

(2014) Kook Hwan Kim et al.   Nature Reviews Endocrinology

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex

(2014) Xiaojuan Chen et al.   Protein & Cell

STING-dependent cytosolic DNA sensing pathways

(2013) Glen N. Barber   TRENDS IN IMMUNOLOGY

The role of autophagy during coxsackievirus infection of neural progenitor and stem cells

(2012) Jenna M. Tabor-Godwin et al.   Autophagy

STING Mediates Neuronal Innate Immune Response Following Japanese Encephalitis Virus Infection

(2012) Arshed Nazmi et al.   Scientific Reports

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Qualitative and quantitative ultrastructural analysis of the membrane rearrangements induced by coronavirus

(2010) Mustafa Ulasli et al.   CELLULAR MICROBIOLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

(2010) J. J. Woodward et al.   SCIENCE

Foot-and-mouth disease virus utilizes an autophagic pathway during viral replication

(2010) Vivian O'Donnell et al.   VIROLOGY

Enterovirus 71-induced autophagy detected in vitro and in vivo promotes viral replication

(2009) Shu-Chen Huang et al.   JOURNAL OF MEDICAL VIROLOGY

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus

(2008) L. M. Hales et al.   JOURNAL OF GENERAL VIROLOGY

Autophagosome Supports Coxsackievirus B3 Replication in Host Cells

(2008) J. Wong et al.   JOURNAL OF VIROLOGY

MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals

(2008) L. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE