The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1

African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity

(2022) Yong Ran et al.   PLoS Pathogens

African Swine Fever Virus MGF360-14L Negatively Regulates Type I Interferon Signaling by Targeting IRF3

(2022) Yang Wang et al.   Frontiers in Cellular and Infection Microbiology

African Swine Fever Virus MGF-505-7R Negatively Regulates cGAS–STING-Mediated Signaling Pathway

(2021) Dan Li et al.   JOURNAL OF IMMUNOLOGY

Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1

(2021) Zhihai Zhou et al.   Frontiers in Immunology

Potential SARS-CoV-2 Immune Correlates of Protection in Infection and Vaccine Immunization

(2021) Yongjun Sui et al.   Pathogens

SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1

(2021) Liyan Sui et al.   Frontiers in Immunology

African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling

(2021) Dan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ASFV bearing an I226R gene-deletion elicits a robust immunity in pigs to African swine fever

(2021) Yanyan Zhang et al.   JOURNAL OF VIROLOGY

African Swine Fever Virus E120R Protein Inhibits Interferon Beta Production by Interacting with IRF3 To Block Its Activation

(2021) Huisheng Liu et al.   JOURNAL OF VIROLOGY

Deletion of A137R gene from the pandemic strain of African swine fever virus is attenuated and offers protection against virulent pandemic virus

(2021) Douglas P. Gladue et al.   JOURNAL OF VIROLOGY

Adaptation of African swine fever virus to HEK293T cells

(2021) Tao Wang et al.   Transboundary and Emerging Diseases

Growth Kinetics and Protective Efficacy of Attenuated ASFV Strain Congo with Deletion of the EP402 Gene

(2021) Galina Koltsova et al.   Viruses-Basel

pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production

(2021) Jiangnan Li et al.   PLoS Pathogens

Deletion of E184L, a Putative DIVA Target from the Pandemic Strain of African Swine Fever Virus, Produces a Reduction in Virulence and Protection against Virulent Challenge

(2021) Elizabeth Ramirez-Medina et al.   JOURNAL OF VIROLOGY

A QP509L/QP383R-Deleted African Swine Fever Virus Is Highly Attenuated in Swine but Does Not Confer Protection against Parental Virus Challenge

(2021) Dan Li et al.   JOURNAL OF VIROLOGY

Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production Due to Aberrant Virion Morphogenesis and Enhances Inflammatory Cytokine Expression in Porcine Macrophages

(2021) Pingping Zhou et al.   JOURNAL OF VIROLOGY

African swine fever virus MGF505-11R inhibits type I interferon production by negatively regulating the cGAS-STING-mediated signaling pathway

(2021) Kaidian Yang et al.   VETERINARY MICROBIOLOGY

Herpes Simplex Virus Type 1 Infection Disturbs the Mitochondrial Network, Leading to Type I Interferon Production through the RNA Polymerase III/RIG-I Pathway

(2021) Noémie Berry et al.   mBio

GABARAPL2 is critical for growth restriction of Toxoplasma gondii in HeLa cells treated with IFN-γ

(2020) Zhaoxia Zhang et al.   INFECTION AND IMMUNITY

Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain.

(2020) Manuel V. Borca et al.   JOURNAL OF VIROLOGY

A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs

(2020) Weiye Chen et al.   Science China-Life Sciences

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine

(2020) Manuel V. Borca et al.   Scientific Reports

Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response

(2020) Hong-Mei Zou et al.   JOURNAL OF VIROLOGY

Deletion of the Gene for the Type I Interferon Inhibitor I329L from the Attenuated African Swine Fever Virus OURT88/3 Strain Reduces Protection Induced in Pigs

(2020) Ana Luisa Reis et al.   Vaccines

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression

(2020) Linda J. Visser et al.   PLoS Pathogens

Generation and Evaluation of an African Swine Fever Virus Mutant with Deletion of the CD2v and UK Genes

(2020) Teshale Teklue et al.   Vaccines

Replication and virulence in pigs of the first African swine fever virus isolated in China

(2019) Dongming Zhao et al.   Emerging Microbes & Infections

Development of vaccines against African swine fever virus

(2019) Elena G. Sánchez et al.   VIRUS RESEARCH

African swine fever virus Armenia/07 virulent strain controls IFN-β production through cGAS-STING pathway

(2019) Raquel García-Belmonte et al.   JOURNAL OF VIROLOGY

Human Hemoglobin Subunit Beta Functions as a Pleiotropic Regulator of RIG-I/MDA5-Mediated Antiviral Innate Immune Responses

(2019) Qian Yang et al.   JOURNAL OF VIROLOGY

African swine fever virus evasion of host defences

(2019) L.K. Dixon et al.   VIRUS RESEARCH

Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex

(2018) Xing Liu et al.   JOURNAL OF VIROLOGY

Poxviral protein E3–altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor–stimulated immune responses

(2018) Alan Dempsey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A proteomic atlas of the African swine fever virus particle

(2018) Alí Alejo et al.   JOURNAL OF VIROLOGY

Emergence of African Swine Fever in China, 2018

(2018) Xintao Zhou et al.   Transboundary and Emerging Diseases

Inhibition of cGAS-STING-TBK1 signaling pathway by DP96R of ASFV China 2018/1

(2018) Xixi Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Zebrafish MVP Recruits and Degrades TBK1 To Suppress IFN Production

(2018) Shun Li et al.   JOURNAL OF IMMUNOLOGY

Japanese Encephalitis Virus NS1′ Protein Antagonizes Interferon Beta Production

(2018) Dengyuan Zhou et al.   VIROLOGICA SINICA

Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase–IRF3 transcription factor interaction and signaling required for interferon induction

(2017) Yun-Jia Ning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BA71ΔCD2: a New Recombinant Live Attenuated African Swine Fever Virus with Cross-Protective Capabilities

(2017) Paula L. Monteagudo et al.   JOURNAL OF VIROLOGY

Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge

(2017) Ana L. Reis et al.   JOURNAL OF VIROLOGY

African Swine Fever Virus: A Review

(2017) et al.   Viruses-Basel

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity

(2016) Lian-Feng Li et al.   JOURNAL OF VIROLOGY

Bluetongue Virus NS4 Protein Is an Interferon Antagonist and a Determinant of Virus Virulence

(2016) Maxime Ratinier et al.   JOURNAL OF VIROLOGY

USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome

(2016) Meng Lin et al.   MOLECULAR CELL

Deletion of African swine fever virus interferon inhibitors from the genome of a virulent isolate reduces virulence in domestic pigs and induces a protective response

(2016) Ana Luisa Reis et al.   VACCINE

African Swine Fever Virus Georgia Isolate Harboring Deletions of MGF360 and MGF505 Genes Is Attenuated in Swine and Confers Protection against Challenge with Virulent Parental Virus

(2015) Vivian O'Donnell et al.   JOURNAL OF VIROLOGY

DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation

(2015) Tai An et al.   PLoS Pathogens

Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5

(2012) J. Xing et al.   JOURNAL OF VIROLOGY

Identification and utility of innate immune system evasion mechanisms of ASFV

(2012) Sílvia Correia et al.   VIRUS RESEARCH

African swine fever virus replication and genomics

(2012) Linda K. Dixon et al.   VIRUS RESEARCH

A novel TLR3 inhibitor encoded by African swine fever virus (ASFV)

(2011) V. L. de Oliveira et al.   ARCHIVES OF VIROLOGY

The Human Cytomegalovirus (HCMV) Tegument Protein UL94 Is Essential for Secondary Envelopment of HCMV Virions

(2011) S. L. Phillips et al.   JOURNAL OF VIROLOGY

Beta Interferon Controls West Nile Virus Infection and Pathogenesis in Mice

(2011) H. M. Lazear et al.   JOURNAL OF VIROLOGY

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

Control of TANK-binding Kinase 1-mediated Signaling by the γ134.5 Protein of Herpes Simplex Virus 1

(2008) Dustin Verpooten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY