Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication

Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo

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Host Calcium Channels and Pumps in Viral Infections

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Induction of autophagy and suppression of type I IFN secretion by CSFV

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Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19

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Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis

(2020) Quangang Chen et al.   Scientific Reports

The SERCA residue Glu340 mediates interdomain communication that guides Ca2+transport

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ZAP, a CCCH-Type Zinc Finger Protein inhibits PRRSV replication and interacts with viral Nsp9

(2019) Yongxiang Zhao et al.   JOURNAL OF VIROLOGY

Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality

(2019) Hao Li et al.   CELL RESEARCH

Porcine deltacoronavirus (PDCoV) modulates calcium influx to favor viral replication

(2019) Dongcheng Bai et al.   VIROLOGY

Induction of the unfolded protein response (UPR) suppresses porcine reproductive and respiratory syndrome virus (PRRSV) replication

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Crosstalk of ER stress-mediated autophagy and ER-phagy: Involvement of UPR and the core autophagy machinery

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The Nucleocapsid Protein and Nonstructural Protein 10 of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Enhance CD83 Production via NF-κB and Sp1 Signaling Pathways

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Pathogenesis and control of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus

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Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Pathogenesis and Interaction with the Immune System

(2016) Joan K. Lunney et al.   Annual Review of Animal Biosciences

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Store-Operated Calcium Channels

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Catch Me If You Can: The Link between Autophagy and Viruses

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Calcium Homeostasis and ER Stress in Control of Autophagy in Cancer Cells

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Ca2+–Sensor Proteins in the Autophagic and Endocytic Traffic

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Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication

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Calcium/Calmodulin-dependent Protein Kinase Kinase 2: Roles in Signaling and Pathophysiology

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Two-Dimensional Liquid Chromatography–Tandem Mass Spectrometry Coupled with Isobaric Tags for Relative and Absolute Quantification (iTRAQ) Labeling Approach Revealed First Proteome Profiles of Pulmonary Alveolar Macrophages Infected with Porcine Reproductive and Respiratory Syndrome Virus

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Autophagy sustains the replication of porcine reproductive and respiratory virus in host cells

(2012) Qinghao Liu et al.   VIROLOGY

A dual role for Ca2+ in autophagy regulation

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Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

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The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins

(2010) Ying Fang et al.   VIRUS RESEARCH

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

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Autophagy, Immunity, and Microbial Adaptations

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The Porcine Reproductive and Respiratory Syndrome Virus nsp2 Cysteine Protease Domain Possesses both trans- and cis-Cleavage Activities

(2009) J. Han et al.   JOURNAL OF VIROLOGY