FADS2 function at the major cancer hotspot 11q13 locus alters fatty acid metabolism in cancer

EGFR Mutation and 11q13 Amplification Are Potential Predictive Biomarkers for Immunotherapy in Head and Neck Squamous Cell Carcinoma

(2022) Shengjin Dou et al.   Frontiers in Immunology

Clinical Impact of 11q13.3 Amplification on Immune Cell Infiltration and Prognosis in Breast Cancer

(2022) Renyu Zhou et al.   International Journal of General Medicine

The association of chromosome 11q13 amplification with the hyperprogressive disease in unresectable hepatocellular carcinoma patients underwent the immunotherapy.

(2022) Haibin Zhang et al.   JOURNAL OF CLINICAL ONCOLOGY

Fatty acid desaturase 1 (FADS1) is a cancer marker for patient survival and a potential novel target for precision cancer treatment

(2022) Gioia Heravi et al.   Frontiers in Oncology

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Colorectal Cancer Incidence After Colonoscopy at Ages 45–49 or 50–54 Years

(2021) Maanek Sehgal et al.   GASTROENTEROLOGY

Apocryphal FADS2 activity promotes fatty acid diversification in cancer

(2021) Reuben S.E. Young et al.   Cell Reports

N-3 Long-Chain Polyunsaturated Fatty Acids, Eicosapentaenoic and Docosahexaenoic Acid, and the Role of Supplementation during Cancer Treatment: A Scoping Review of Current Clinical Evidence

(2021) Marnie Newell et al.   Cancers

The aromatase inhibitor letrozole restores FADS2 function in ER+ MCF7 human breast cancer cells

(2021) Hui Gyu Park et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

New understandings of the pathway of long-chain polyunsaturated fatty acid biosynthesis

(2021) J. Thomas Brenna et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Long-range promoter–enhancer contacts are conserved during evolution and contribute to gene expression robustness

(2021) Alexandre Laverré et al.   GENOME RESEARCH

Risk SNP-mediated enhancer-promoter interaction drives colorectal cancer through both FADS2 and AP002754.2

(2020) Jianbo Tian et al.   CANCER RESEARCH

Cross-Cancer Pleiotropic Analysis Reveals Novel Susceptibility Loci for Lung Cancer

(2020) Lijuan Wang et al.   Frontiers in Oncology

The landscape of chromosome 11q13 amplification in Chinese solid tumor patients and hyperprogressive disease (HPD) clinical example.

(2020) Jieli Yu et al.   JOURNAL OF CLINICAL ONCOLOGY

Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden

(2020) Tao Qing et al.   Nature Communications

Expression of SCD and FADS2 Is Lower in the Necrotic Core and Growing Tumor Area than in the Peritumoral Area of Glioblastoma Multiforme

(2020) Jan Korbecki et al.   Biomolecules

CircFADS2: A potential prognostic biomarker of colorectal cancer

(2020) Yi-Sheng Xiao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis

(2020) Mouna Triki et al.   Cell Reports

Docosahexaenoic Acid Reverted the All-trans Retinoic Acid-Induced Cellular Proliferation of T24 Bladder Cancer Cell Line

(2020) Lara Costantini et al.   Journal of Clinical Medicine

The Origin of Ovarian Cancer Species and Precancerous Landscape

(2020) Ie-Ming Shih et al.   AMERICAN JOURNAL OF PATHOLOGY

Network-based method for regions with statistically frequent interchromosomal interactions at single-cell resolution

(2020) Chanaka Bulathsinghalage et al.   BMC BIOINFORMATICS

Clinicopathological and genomic features of breast mucinous carcinoma

(2020) Kebin Lu et al.   BREAST

FADS1 is a Prognostic Biomarker in Bladder Cancer: A Study Based on TCGA Data

(2020) Ying Lu et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Urinary biomarkers in bladder cancer: A review of the current landscape and future directions

(2020) Kenrick Ng et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer

(2020) Fangdong Jiao et al.   Cancer Management and Research

Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer

(2020) Ji-Yoon Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans

(2020) SB Rifkin et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

(2019) Kim Vriens et al.   NATURE

Tumours use a metabolic twist to make lipids

(2019) Marteinn Thor Snaebjornsson et al.   NATURE

Integrative molecular profiling identifies a novel cluster of ER-positive breast cancer in very young women

(2019) Charny Park et al.   CANCER SCIENCE

Ovarian Cancer: An Integrated Review

(2019) Christine Stewart et al.   Seminars in Oncology Nursing

Association of frequent amplification of chromosome 11q13 in esophageal squamous cell cancer with clinical benefit to immune check point blockade.

(2019) Feng Wang et al.   JOURNAL OF CLINICAL ONCOLOGY

Circular RNAs and RNA Splice Variants as Biomarkers for Prognosis and Therapeutic Response in the Liquid Biopsies of Lung Cancer Patients

(2019) Florence de Fraipont et al.   Frontiers in Genetics

Low eicosapentaenoic acid and gamma-linolenic acid levels in breast adipose tissue are associated with inflammatory breast cancer

(2019) Marie Chas et al.   BREAST

Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death

(2019) Lia Tesfay et al.   CANCER RESEARCH

101PPan-cancer genomic landscape of the cyclin D1/FGF3,4,19 (11q13) amplicon including associations with HPV status, and ESR1 and AR alterations

(2019) A B Schrock et al.   ANNALS OF ONCOLOGY

Overview of the relevance of PI3K pathway in HR-positive breast cancer

(2019) N Vasan et al.   ANNALS OF ONCOLOGY

Stearoyl CoA Desaturase Regulates Ferroptosis in Ovarian Cancer Offering New Therapeutic Perspectives

(2019) Michele Carbone et al.   CANCER RESEARCH

Clinical Features of Neuroblastoma With 11q Deletion: An Increase in Relapse Probabilities In Localized And 4S Stages

(2019) Antonio J Ribelles et al.   Scientific Reports

Comprehensive Genomic Review of TCGA Head and Neck Squamous Cell Carcinomas (HNSCC)

(2019) Mario Pérez Sayáns et al.   Journal of Clinical Medicine

FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome

(2019) Gergely Karsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic Landscape of Intramedullary Spinal Cord Gliomas

(2019) Ming Zhang et al.   Scientific Reports

A regulatory insertion-deletion polymorphism in the FADS gene cluster influences PUFA and lipid profiles among Chinese adults: a population-based study

(2018) Peiqin Li et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring

(2018) Elias Jabbour et al.   AMERICAN JOURNAL OF HEMATOLOGY

circFADS2 regulates lung cancer cells proliferation and invasion via acting as a sponge of miR-498

(2018) Fucheng Zhao et al.   BIOSCIENCE REPORTS

Comparative Molecular Analyses of Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, and Gastric Adenocarcinoma

(2018) Mohamed E. Salem et al.   ONCOLOGIST

Oncogenic drivers in 11q13 associated with prognosis and response to therapy in advanced oropharyngeal carcinomas

(2018) M.C. Barros-Filho et al.   ORAL ONCOLOGY

The role of fatty acid desaturase (FADS) genes in oleic acid metabolism: FADS1 Δ7 desaturates 11-20:1 to 7,11-20:2

(2018) Hui Gyu Park et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A novel FADS2 isoform identified in human milk fat globule suppresses FADS2 mediated Δ6-desaturation of omega-3 fatty acids

(2018) Kumar S.D. Kothapalli et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Dietary n-3 and n-6 polyunsaturated fatty acids, the FADS gene, and the risk of gastric cancer in a Korean population

(2018) Sunghee Lee et al.   Scientific Reports

Conversion of dietary trans-vaccenic acid to trans11,cis13-conjugated linoleic acid in the rat lactating mammary gland by Fatty Acid Desaturase 3-catalyzed methyl-end Δ13-desaturation

(2018) Cyrielle Garcia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Abstract 4349: Higher level of tumor mutational burden and 11q13 amplification in Chinese hepatocellular carcinoma patients

(2018) Xiaofeng Tang et al.   CANCER RESEARCH

Function and clinical significance of circRNAs in solid tumors

(2018) Yiting Geng et al.   Journal of Hematology & Oncology

Decreased Oleic Acid and Marine n − 3 Polyunsaturated Fatty Acids in Tunisian Patients with Urothelial Bladder Cancer

(2018) Mohamed Kacem Ben Fradj et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity

(2018) Prachi Jain et al.   STEM CELLS

Amplicons in breast cancers analyzed by multiplex ligation-dependent probe amplification and fluorescence In Situ hybridization

(2018) Akishi Ooi et al.   HUMAN PATHOLOGY

Cyclooxygenase-2 in cancer: A review

(2018) Nasser Hashemi Goradel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

New insights on the regulation of cancer cachexia by N-3 polyunsaturated fatty acids

(2018) Renata Gorjao et al.   PHARMACOLOGY & THERAPEUTICS

11q deletion in neuroblastoma: a review of biological and clinical implications

(2017) Vid Mlakar et al.   Molecular Cancer

Fish intake and the risk of brain tumor: a meta-analysis with systematic review

(2017) Wei Lian et al.   Nutrition Journal

Relevance of chromosomal band 11q13 in oral carcinogenesis: An update of current knowledge

(2017) Pablo Ramos-García et al.   ORAL ONCOLOGY

Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma

(2017) Angela B. Ortiz et al.   PLoS One

Molecular characteristics and clinical outcomes of EGFR exon 19 indel subtypes to EGFR TKIs in NSCLC patients

(2017) Jian Su et al.   Oncotarget

Renal cell carcinoma: the search for a reliable biomarker

(2017) Nicholas J. Farber et al.   Translational Cancer Research

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015

(2017) et al.   JAMA Oncology

Fish oil-enriched nutrition combined with systemic chemotherapy for gastrointestinal cancer patients with cancer cachexia

(2017) Yumiko Shirai et al.   Scientific Reports

Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation

(2016) Hui Gyu Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Understanding and effectively addressing breast cancer in African American women: Unpacking the social context

(2016) David R. Williams et al.   CANCER

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Desaturase and elongase-limiting endogenous long-chain polyunsaturated fatty acid biosynthesis

(2016) Ji Yao Zhang et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Positive Selection on a Regulatory Insertion–Deletion Polymorphism inFADS2Influences Apparent Endogenous Synthesis of Arachidonic Acid

(2016) Kumar S. D. Kothapalli et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

(2016) S. P. Kar et al.   Cancer Discovery

Patterns and Trends in Age-Specific Black-White Differences in Breast Cancer Incidence and Mortality – United States, 1999–2014

(2016) Lisa C. Richardson et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Admixture Mapping of African–American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes

(2016) Edward A. Ruiz-Narváez et al.   Frontiers in Genetics

Decreased Expression of FADS1 Predicts a Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma

(2015) Yong Du et al.   Asian Pacific Journal of Cancer Prevention

The fatty acid desaturase 2 (FADS2) gene product catalyzes Δ4 desaturation to yield n-3 docosahexaenoic acid and n-6 docosapentaenoic acid in human cells

(2015) Hui Gyu Park et al.   FASEB JOURNAL

COX/mPGES-1/PGE2pathway depicts an inflammatory-dependent high-risk neuroblastoma subset

(2015) Karin Larsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative genomic hybridization analysis of invasive ductal breast carcinomas in the Chinese population

(2015) JIANWEI ZHANG et al.   Oncology Letters

Clinical relevance of copy number profiling in oral and oropharyngeal squamous cell carcinoma

(2015) Pauline M. W. van Kempen et al.   Cancer Medicine

Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

(2015) Veronique Mathieu et al.   Oncotarget

Prostaglandin E3 metabolism and cancer

(2014) Peiying Yang et al.   CANCER LETTERS

One in four individuals of African-American ancestry harbors a 5.5 kb deletion at chromosome 11q13.1

(2014) Kayvan Zainabadi et al.   GENOMICS

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

(2014) Ben Zhang et al.   NATURE GENETICS

Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population

(2014) Qingyi Wei et al.   NATURE GENETICS

Loss of FADS2 Function Severely Impairs the Use of HeLa Cells as an In Vitro Model for Host Response Studies Involving Fatty Acid Effects

(2014) Anke Jaudszus et al.   PLoS One

Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival

(2014) Nidhan K. Biswas et al.   Nature Communications

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer

(2013) Kristen S. Purrington et al.   CARCINOGENESIS

Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies

(2013)   LANCET ONCOLOGY

Interaction of brain fatty acid-binding protein with the polyunsaturated fatty acid environment as a potential determinant of poor prognosis in malignant glioma

(2013) Marwa E. Elsherbiny et al.   PROGRESS IN LIPID RESEARCH

Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids

(2013) Nousheen Zaidi et al.   PROGRESS IN LIPID RESEARCH

Omega-3 Fatty Acids Inhibit Tumor Growth in a Rat Model of Bladder Cancer

(2013) Belmiro Parada et al.   Biomed Research International

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

the 11q13-q14 amplicon: Clinicopathological correlations and potential drivers

(2012) Paul M. Wilkerson et al.   GENES CHROMOSOMES & CANCER

11q13 is a susceptibility locus for hormone receptor positive breast cancer

(2012) Diether Lambrechts et al.   HUMAN MUTATION

A novelFADS1isoform potentiatesFADS2-mediated production of eicosanoid precursor fatty acids

(2012) Woo Jung Park et al.   JOURNAL OF LIPID RESEARCH

High levels of arachidonic acid and peroxisome proliferator-activated receptor-alpha in breast cancer tissues are associated with promoting cancer cell proliferation

(2012) Nai-Wen Chang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese

(2012) Shusuke Akamatsu et al.   NATURE GENETICS

Insertion–deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin

(2012) Holly T. Reardon et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Characterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours

(2011) Karolina Holm et al.   BREAST CANCER RESEARCH AND TREATMENT

High-resolution genomic analysis of the 11q13 amplicon in breast cancers identifies synergy with 8p12 amplification, involving the mTOR targets S6K2 and 4EBP1

(2011) Elin Karlsson et al.   GENES CHROMOSOMES & CANCER

Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

(2011) Todd W. Miller et al.   JOURNAL OF CLINICAL ONCOLOGY

The polypyrimidine tract binding protein regulates desaturase alternative splicing and PUFA composition

(2011) Holly T. Reardon et al.   JOURNAL OF LIPID RESEARCH

Copy Number Gains in 11q13 and 8q34 Are Highly Linked to Prognosis in Cutaneous Malignant Melanoma

(2011) Pedram Gerami et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

FADS2 Function Loss at the Cancer Hotspot 11q13 Locus Diverts Lipid Signaling Precursor Synthesis to Unusual Eicosanoid Fatty Acids

(2011) Woo Jung Park et al.   PLoS One

Regulation of inflammation in cancer by eicosanoids

(2011) Emily R. Greene et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Sensitivity of Fluorescence In Situ Hybridization for Melanoma Diagnosis Using RREB1, MYB, Cep6, and 11q13 Probes in Melanoma Subtypes

(2010) Pedram Gerami et al.   ARCHIVES OF DERMATOLOGY

Prevalence of a History of Skin Cancer in 2007

(2010) Robert S. Stern   ARCHIVES OF DERMATOLOGY

Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours

(2010) F Caiazza et al.   BRITISH JOURNAL OF CANCER

Cytochrome P450-derived eicosanoids: the neglected pathway in cancer

(2010) Dipak Panigrahy et al.   CANCER AND METASTASIS REVIEWS

Cyclooxygenase-2 in oncogenesis

(2010) Maria Teresa Rizzo   CLINICA CHIMICA ACTA

Lobular invasive carcinoma of the breast is a molecular entity distinct from luminal invasive ductal carcinoma

(2010) Nadège Gruel et al.   EUROPEAN JOURNAL OF CANCER

Lean body mass gain in patients with head and neck squamous cell cancer treated perioperatively with a protein- and energy-dense nutritional supplement containing eicosapentaenoic acid

(2010) Harrison G. Weed et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Oral Nutritional Supplements Containing (n-3) Polyunsaturated Fatty Acids Affect the Nutritional Status of Patients with Stage III Non-Small Cell Lung Cancer during Multimodality Treatment

(2010) Barbara S. van der Meij et al.   JOURNAL OF NUTRITION

Cytosolic Phospholipase A2Activation Correlates with HER2 Overexpression and Mediates Estrogen-Dependent Breast Cancer Cell Growth

(2010) Francesco Caiazza et al.   MOLECULAR ENDOCRINOLOGY

Genome-wide association study identifies five new breast cancer susceptibility loci

(2010) Clare Turnbull et al.   NATURE GENETICS

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells

(2010) Paula M. Maloberti et al.   PLoS One

Alternative transcripts of fatty acid desaturase (FADS) genes

(2010) J. Thomas Brenna et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) Preserves Lean Body Mass Following Esophageal Cancer Surgery: Results of a Double-Blinded Randomized Controlled Trial

(2009) Aoife M. Ryan et al.   ANNALS OF SURGERY

Non-methylene-interrupted fatty acids from marine invertebrates: Occurrence, characterization and biological properties

(2009) Gilles Barnathan   BIOCHIMIE

A 7 Mb region within 11q13 may contain a high penetrance gene for breast cancer

(2009) Juan Manuel Rosa-Rosa et al.   BREAST CANCER RESEARCH AND TREATMENT

Two Independent Prostate Cancer Risk-Associated Loci at 11q13

(2009) S. L. Zheng et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Novel fatty acid desaturase 3 (FADS3) transcripts generated by alternative splicing

(2009) Woo Jung Park et al.   GENE

High CCND1 amplification identifies a group of poor prognosis women with estrogen receptor positive breast cancer

(2009) Pankaj G. Roy et al.   INTERNATIONAL JOURNAL OF CANCER

Alternative splicing generates a novel FADS2 alternative transcript in baboons

(2009) Woo Jung Park et al.   MOLECULAR BIOLOGY REPORTS

Focal amplification and oncogene dependency of GAB2 in breast cancer

(2009) M Bocanegra et al.   ONCOGENE

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Amplification of HER2 is a marker for global genomic instability

(2008) Rachel E Ellsworth et al.   BMC CANCER

Amplification of 11q13 in ovarian carcinoma

(2008) Lindsay A. Brown et al.   GENES CHROMOSOMES & CANCER

Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions

(2008) Britta Skawran et al.   MODERN PATHOLOGY

Multiple loci identified in a genome-wide association study of prostate cancer

(2008) Gilles Thomas et al.   NATURE GENETICS

Multiple newly identified loci associated with prostate cancer susceptibility

(2008) Rosalind A Eeles et al.   NATURE GENETICS

The functional impact of structural variation in humans

(2008) Matthew E. Hurles et al.   TRENDS IN GENETICS

Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology

(2008) Hedi Harizi et al.   TRENDS IN MOLECULAR MEDICINE