Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity

Aberrant lipid metabolism in cancer cells - the role of oncolipid-activated signaling

(2017) Upasana Ray et al.   FEBS Journal

Lkb1 regulation of skeletal muscle development, metabolism and muscle progenitor cell homeostasis

(2017) Tizhong Shan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier

(2017) Wilhelm Stoffel et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A pathology atlas of the human cancer transcriptome

(2017) Mathias Uhlen et al.   SCIENCE

Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity

(2016) Weina Zhao et al.   CANCER RESEARCH

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis

(2016) F. Geng et al.   CLINICAL CANCER RESEARCH

Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation

(2016) Alex B Wang et al.   EMBO JOURNAL

Saturated Branched Chain, Normal Odd-Carbon-Numbered, and n-3 (Omega-3) Polyunsaturated Fatty Acids in Freshwater Fish in the Northeastern United States

(2016) Dong Hao Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lipid profile in patients with androgenetic alopecia: a meta-analysis

(2016) M.W. Kim et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

(2016) Semir Beyaz et al.   NATURE

Peroxisomal Lipid Synthesis Regulates Inflammation by Sustaining Neutrophil Membrane Phospholipid Composition and Viability

(2015) Irfan J. Lodhi et al.   Cell Metabolism

Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease

(2015) Laura K. Hamilton et al.   Cell Stem Cell

Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells

(2015) Xiongwei Cai et al.   Cell Stem Cell

The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health

(2014) Maitane Ibarguren et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

(2014) Shuhua Yue et al.   Cell Metabolism

Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer

(2014) Maria M. Mihaylova et al.   Cell Stem Cell

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators

(2014) Wen-Hui Lien et al.   NATURE CELL BIOLOGY

HCV 3a Core Protein Increases Lipid Droplet Cholesteryl Ester Content via a Mechanism Dependent on Sphingolipid Biosynthesis

(2014) Ursula Loizides-Mangold et al.   PLoS One

High Runx1 Levels Promote a Reversible, More-Differentiated Cell State in Hair-Follicle Stem Cells during Quiescence

(2014) Song Eun Lee et al.   Cell Reports

Control of Lipid Metabolism by Tachykinin in Drosophila

(2014) Wei Song et al.   Cell Reports

Wnt signaling in adult intestinal stem cells and cancer

(2013) Michaela Krausova et al.   CELLULAR SIGNALLING

Fluorescent Probes for Lipid Rafts: From Model Membranes to Living Cells

(2013) Andrey S. Klymchenko et al.   CHEMISTRY & BIOLOGY

Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma

(2013) C. A. von Roemeling et al.   CLINICAL CANCER RESEARCH

Runx1 and p21 synergistically limit the extent of hair follicle stem cell quiescence in vivo

(2013) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

(2013) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Regulation of Stem Cell Proliferation and Differentiation by Essential Fatty Acids and Their Metabolites

(2013) Jing X. Kang et al.   STEM CELLS

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

(2013) A Noto et al.   Cell Death & Disease

Impact of Lipid Nutrition on Neural Stem/Progenitor Cells

(2013) Nobuyuki Sakayori et al.   Stem Cells International

Fate through Fat: Lipid Metabolism Determines Stem Cell Division Outcome

(2012) Rushdia Zareen Yusuf et al.   Cell Metabolism

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

(2012) Monika Lichtinger et al.   EMBO JOURNAL

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

(2012) Cornelia Johanna Franziska Scheitz et al.   EMBO JOURNAL

New insights into the role of Runx1 in epithelial stem cell biology and pathology

(2012) Cornelia Johanna Franziska Scheitz et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

(2012) Marlen Knobloch et al.   NATURE

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

(2012) Juxue Li et al.   NATURE CELL BIOLOGY

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

SCD1 Inhibition Causes Cancer Cell Death by Depleting Mono-Unsaturated Fatty Acids

(2012) Paul Mason et al.   PLoS One

Laurdan generalized polarization fluctuations measures membrane packing micro-heterogeneity in vivo

(2012) S. A. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hairy tale of signaling in hair follicle development and cycling

(2012) Jayhun Lee et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

(2011) Karen M. Osorio et al.   JOURNAL OF CELL BIOLOGY

Structural characterization of saturated branched chain fatty acid methyl esters by collisional dissociation of molecular ions generated by electron ionization

(2011) Rinat R. Ran-Ressler et al.   JOURNAL OF LIPID RESEARCH

Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation

(2011) Seung-Jin Kim et al.   MOLECULES AND CELLS

Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis

(2011) R. Ariel Igal   Cancers

Loss of stearoyl-CoA desaturase activity leads to free cholesterol synthesis through increased Xbp-1 splicing

(2010) Chad M. Paton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mutations in Sterol O-Acyltransferase 1 (Soat1) Result in Hair Interior Defects in AKR/J Mice

(2010) Baojin Wu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Runx1 Directly Promotes Proliferation of Hair Follicle Stem Cells and Epithelial Tumor Formation in Mouse Skin

(2010) C. S. L. Hoi et al.   MOLECULAR AND CELLULAR BIOLOGY

Identifying significant genetic regulatory networks in the prostate cancer from microarray data based on transcription factor analysis and conditional independency

(2009) Hsiang-Yuan Yeh et al.   BMC Medical Genomics

High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation

(2009) Caryl J. Antalis et al.   BREAST CANCER RESEARCH AND TREATMENT

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

(2009) Valentina Greco et al.   Cell Stem Cell

Membrane glycolipids in stem cells

(2009) Robert K. Yu et al.   FEBS LETTERS

Skin-specific Deletion of Stearoyl-CoA Desaturase-1 Alters Skin Lipid Composition and Protects Mice from High Fat Diet-induced Obesity

(2009) Harini Sampath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors

(2008) Zhili Xin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Runx1 modulates developmental, but not injury-driven, hair follicle stem cell activation

(2008) K. M. Osorio et al.   DEVELOPMENT

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cholesterol esterification reduces the neurotoxicity of prions

(2008) C BATE et al.   NEUROPHARMACOLOGY