Nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites in cell and organ cultures: current status and future outlooks

Are silver nanoparticles the “silver bullet” to promote diterpene production in Stevia rebaudiana?

(2023) Ivan Andújar et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Glucotropaeolin Promotes Apoptosis by Calcium Dysregulation and Attenuates Cell Migration with FOXM1 Suppression in Pancreatic Cancer Cells

(2023) Woonghee Lee et al.   Antioxidants

Production of anthraquinones from cell and organ cultures of Morinda species

(2023) Hosakatte Niranjana Murthy et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Multilevel approach to plant–nanomaterial relationships: from cells to living ecosystems

(2023) Halley Caixeta Oliveira et al.   JOURNAL OF EXPERIMENTAL BOTANY

Bioreactor systems for micropropagation of plants: present scenario and future prospects

(2023) Hosakatte Niranjana Murthy et al.   Frontiers in Plant Science

Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites

(2023) Hosakatte Niranjana Murthy et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

(2022) Praveen Dhyani et al.   Cancer Cell International

Untargeted metabolomics analysis reveals the elicitation of important secondary metabolites upon treatment with various metal and metal oxide nanoparticles in Hypericum perforatum L. cell suspension cultures

(2022) Dariusz Kruszka et al.   INDUSTRIAL CROPS AND PRODUCTS

Stimulation of phenolic compounds accumulation and antioxidant activity in in vitro culture of Salvia tebesana Bunge in response to nano-TiO2 and methyl jasmonate elicitors

(2022) Amin Allah Shoja et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Evaluation of synthesized magnetic nanoparticles and salicylic acid effects on improvement of antioxidant properties and essential oils of Calotropis procera hairy roots and seedlings

(2022) Fatemeh Adabavazeh et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Influence of Ag nanoparticles on physiological and biochemical aspects of callus of Thymus species and Zataria multiflora Boiss.

(2022) Nima MOSAVAT et al.   Acta Agriculturae Slovenica

The purview of doped nanoparticles: Insights into their biomedical applications

(2022) Raghavendra Udaya Kumar Shenoy et al.   OpenNano

Impact of elicitors on essential oil compositions and phytochemical constituents in Lavandula stoechas L.

(2022) Majid Vakil Asadollahei et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview

(2022) Hosakatte Niranjana Murthy et al.   Metabolites

Responses of Medicinal and Aromatic Plants to Engineered Nanoparticles

(2021) Katarina Kralova et al.   Applied Sciences-Basel

Nano-Elicitation as an Effective and Emerging Strategy for In Vitro Production of Industrially Important Flavonoids

(2021) Amna Komal Khan et al.   Applied Sciences-Basel

Nanoparticles as Novel Elicitors to Improve Bioactive Compounds in Plants

(2021) Samantha de Jesus Rivero-Montejo et al.   Agriculture-Basel

Iron and zinc oxide nanoparticles: An efficient elicitor to enhance trigonelline alkaloid production in hairy roots of fenugreek

(2021) Neda Tariverdizadeh et al.   INDUSTRIAL CROPS AND PRODUCTS

Enhancement of Celastrol compound by silver nanoparticles and acetosyringone in Celastrus paniculatus Willd. through adventitious and hairy root culture

(2021) Anil Kumar Moola et al.   JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY

Unraveling the roles of plant specialized metabolites: using synthetic biology to design molecular biosensors

(2021) Constantine Garagounis et al.   NEW PHYTOLOGIST

Plant Secondary Metabolite Biosynthesis and Transcriptional Regulation in Response to Biotic and Abiotic Stress Conditions

(2021) Rahmatullah Jan et al.   Agronomy-Basel

Iron-doped zinc oxide nanoparticles-triggered elicitation of important phenolic compounds in cell cultures of Fagonia indica

(2021) Atta Ullah Khan et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Bio nanoparticles as elicitors increase accumulation of betulin and betulinic acid in callus cultures

(2021) Payamnoor Vahide et al.   SOUTH AFRICAN JOURNAL OF BOTANY

A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis

(2021) Katrina Weston-Green et al.   Frontiers in Psychiatry

Designer nanoparticles for plant cell culture systems: Mechanisms of elicitation and harnessing of specialized metabolites

(2021) Sagar S. Arya et al.   BIOESSAYS

New Synthetic Caffeine Analogs as Modulators of the Cholinergic System

(2021) Camila Fabiani et al.   MOLECULAR PHARMACOLOGY

Impact of Metallic Nanoparticles on In Vitro Culture, Phenolic Profile and Biological Activity of Two Mediterranean Lamiaceae Species: Lavandula viridis L’Hér and Thymus lotocephalus G. López and R. Morales

(2021) Sandra Gonçalves et al.   MOLECULES

Green (cell) factories for advanced production of plant secondary metabolites

(2020) Andrey S. Marchev et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

A Smart Strategy to Improve t-Resveratrol Production in Grapevine Cells Treated with Cyclodextrin Polymers Coated with Magnetic Nanoparticles

(2020) Lorena Almagro et al.   Polymers

Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health

(2020) Bahare Salehi et al.   ACS Omega

Cell line selection through gamma irradiation combined with multi-walled carbon nanotubes elicitation enhanced phenolic compounds accumulation in Salvia nemorosa cell culture

(2020) Hamid Reza Heydari et al.   PLANT CELL TISSUE AND ORGAN CULTURE

New Relevant Descriptor of Linear QNAR Models for Toxicity Assessment of Silver Nanoparticles

(2020) Alexey Kudrinskiy et al.   Nanomaterials

Comparative analysis of the effects of chemically and biologically synthesized silver nanoparticles on biomass accumulation and secondary metabolism in callus cultures of Fagonia indica

(2020) Shabana Begum et al.   PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS

Effects of Biogenic Zinc Oxide Nanoparticles on Growth and Oxidative Stress Response in Flax Seedlings vs. In Vitro Cultures: A Comparative Analysis

(2020) Afifa Zaeem et al.   Biomolecules

Stimulation of tanshinone production in Salvia miltiorrhiza hairy roots by β -cyclodextrin-coated silver nanoparticles

(2020) Yan Jun Ma et al.   Sustainable Chemistry and Pharmacy

Induction of secondary metabolites on nanoparticles stress in callus culture of Artemisia annua L.

(2020) K. Fatima et al.   BRAZILIAN JOURNAL OF BIOLOGY

Nanoparticles in Agroindustry: Applications, Toxicity, Challenges, and Trends

(2020) Luis A. Paramo et al.   Nanomaterials

Effect of AuNPs and AgNPs on the Antioxidant System and Antioxidant Activity of Lavender (Lavandula angustifolia Mill.) from In Vitro Cultures

(2020) Paula Jadczak et al.   MOLECULES

Modulation of callus growth and secondary metabolites in different Thymus species and Zataria multiflora micropropagated under ZnO nanoparticles stress

(2019) Nima Mosavat et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Silver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata

(2019) Amir Ali et al.   Artificial Cells Nanomedicine and Biotechnology

Impacts of Silver Nanoparticles on Plants: A Focus on the Phytotoxicity and Underlying Mechanism

(2019) An Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biogenic zinc oxide nanoparticles-enhanced biosynthesis of lignans and neolignans in cell suspension cultures of Linum usitatissimum L

(2019) Bilal Haider Abbasi et al.   Artificial Cells Nanomedicine and Biotechnology

Impact of Copper Oxide Nanoparticles on Enhancement of Bioactive Compounds Using Cell Suspension Cultures of Gymnema sylvestre (Retz.) R. Br

(2019) Ill-Min Chung et al.   Applied Sciences-Basel

Iron oxide nanoparticle a novel elicitor to enhancing anticancer flavonoid production and gene expression in Dracocephalum kotschyi hairy root cultures

(2019) Elnaz Nourozi et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

The Structure and Function of Major Plant Metabolite Modifications

(2019) Shouchuang Wang et al.   Molecular Plant

Sustainable production of biomass and industrially important secondary metabolites in cell cultures of selfheal (Prunella vulgaris L.) elicited by silver and gold nanoparticles

(2019) Hina Fazal et al.   Artificial Cells Nanomedicine and Biotechnology

Enhanced production of cichoric acid in cell suspension culture of Echinacea purpurea by silver nanoparticle elicitation

(2019) Rezvan Ramezannezhad et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Effects of Nanoparticles on Activity of Lignan Biosynthesis Enzymes in Cell Suspension Culture of Linum usitatissimum L.

(2019) F. Karimzadeh et al.   RUSSIAN JOURNAL OF PLANT PHYSIOLOGY

Effect of explant source, perlite nanoparticles and TiO2/perlite nanocomposites on phytochemical composition of metabolites in callus cultures of Hypericum perforatum

(2019) R. Ebadollahi et al.   Scientific Reports

Quantitative structure–activity relationships analysis, homology modeling, docking and molecular dynamics studies of triterpenoid saponins as Kirsten rat sarcoma inhibitors

(2019) Mourad Stitou et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Effect of silver nanoparticles on phenolic compounds production and biological activities in hairy root cultures of Cucumis anguria

(2018) Ill-Min Chung et al.   ACTA BIOLOGICA HUNGARICA

Quality, safety and efficacy profiling of ginseng adventitious roots produced in vitro

(2018) Hosakatte Niranjana Murthy et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Advances and current challenges in calcium signaling

(2018) Jörg Kudla et al.   NEW PHYTOLOGIST

Toxicity impacts of chemically and biologically synthesized CuO nanoparticles on cell suspension cultures of Nicotiana tabacum

(2018) Sepideh Mahjouri et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Production of bioactive compounds and gene expression alterations in hairy root cultures of chinese cabbage elicited by copper oxide nanoparticles

(2018) Ill-Min Chung et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Elicitation of Stevia Glycosides Using Salicylic Acid and Silver Nanoparticles Under Callus Culture

(2018) Pooran Golkar et al.   Sugar Tech

Influence of nano-zinc oxide on tropane alkaloid production, h6h gene transcription and antioxidant enzyme activity in Hyoscyamus reticulatus L. hairy roots

(2018) Kamal Rashidi Asl et al.   ENGINEERING IN LIFE SCIENCES

Nanoparticles alter the withanolide biosynthesis and carbohydrate metabolism in Withania somnifera (Dunal)

(2018) Ruchi Singh et al.   INDUSTRIAL CROPS AND PRODUCTS

Chemogenic silver nanoparticles enhance lignans and neolignans in cell suspension cultures of Linum usitatissimum L.

(2018) Adnan Zahir et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Enhanced production of hyoscyamine and scopolamine from genetically transformed root culture of Hyoscyamus reticulatus L. elicited by iron oxide nanoparticles

(2017) Fereshte Moharrami et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Taxanes content and cytotoxicity of hazel cells extract after elicitation with silver nanoparticles

(2017) Mitra Jamshidi et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

An overview on manufactured nanoparticles in plants: Uptake, translocation, accumulation and phytotoxicity

(2017) Durgesh Kumar Tripathi et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Exposure to silver nanoparticles produces oxidative stress and affects macromolecular and metabolic biomarkers in the goodeid fish Chapalichthys pardalis

(2017) Roberto Carlos Valerio-García et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Nanomaterials in plant tissue culture: the disclosed and undisclosed

(2017) Doo Hwan Kim et al.   RSC Advances

Nanoparticles Alter Secondary Metabolism in Plants via ROS Burst

(2017) Gregory Marslin et al.   Frontiers in Plant Science

Elicitation of Secondary Metabolites in Callus Cultures of Stevia rebaudiana Bertoni Grown Under ZnO and CuO Nanoparticles Stress

(2017) Rabia Javed et al.   Sugar Tech

Elicitation of Medicinally Important Antioxidant Secondary Metabolites with Silver and Gold Nanoparticles in Callus Cultures of Prunella vulgaris L.

(2016) Hina Fazal et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Use of magnetic nanoparticles to enhance bioethanol production in syngas fermentation

(2016) Young-Kee Kim et al.   BIORESOURCE TECHNOLOGY

Plant cell culture strategies for the production of natural products

(2016) Marisol Ochoa-Villarreal et al.   BMB Reports

Harnessing the Power of Cruciferous Vegetables: Developing a Biomarker for Brassica Vegetable Consumption Using Urinary 3,3'-Diindolylmethane

(2016) N. Fujioka et al.   Cancer Prevention Research

The effect of silver nanoparticles and silver ions on mammalian and plant cells in vitro

(2016) Jana Jiravova et al.   FOOD AND CHEMICAL TOXICOLOGY

Sinigrin and Its Therapeutic Benefits

(2016) Anisha Mazumder et al.   MOLECULES

Engineered nanomaterial-mediated changes in the metabolism of terrestrial plants

(2016) Mehrnaz Hatami et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Nanotechnology: A New Opportunity in Plant Sciences

(2016) Peng Wang et al.   TRENDS IN PLANT SCIENCE

Ethylene Response Factor TERF1, Regulated by ETHYLENE-INSENSITIVE3-like Factors, Functions in Reactive Oxygen Species (ROS) Scavenging in Tobacco (Nicotiana tabacum L.)

(2016) Hongbo Zhang et al.   Scientific Reports

Effect of the surface modification, size, and shape on cellular uptake of nanoparticles

(2015) Sara Salatin et al.   CELL BIOLOGY INTERNATIONAL

The safety assessment of food ingredients derived from plant cell, tissue and organ cultures: A review

(2015) Hosakatte Niranjana Murthy et al.   FOOD CHEMISTRY

Critical Review on the Toxicity of Some Widely Used Engineered Nanoparticles

(2015) Varsha Srivastava et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Silver sulfide nanoparticles (Ag2S-NPs) are taken up by plants and are phytotoxic

(2015) Peng Wang et al.   Nanotoxicology

Interplay of Reactive Oxygen Species and Nitric Oxide: Nitric Oxide Coordinates Reactive Oxygen Species Homeostasis

(2015) Christian Lindermayr et al.   PLANT PHYSIOLOGY

Proteomics study of silver nanoparticles toxicity on Oryza sativa L.

(2014) Fateme Mirzajani et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mechanisms of nanotoxicity: Generation of reactive oxygen species

(2014) Peter P. Fu et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Exposure of cerium oxide nanoparticles to kidney bean shows disturbance in the plant defense mechanisms

(2014) Sanghamitra Majumdar et al.   JOURNAL OF HAZARDOUS MATERIALS

Fate of pristine TiO2 nanoparticles and aged paint-containing TiO2 nanoparticles in lettuce crop after foliar exposure

(2014) Camille Larue et al.   JOURNAL OF HAZARDOUS MATERIALS

Tools for biotechnological production of useful phytochemicals from adventitious root cultures

(2014) Hosakatte Niranjana Murthy et al.   PHYTOCHEMISTRY REVIEWS

Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation

(2014) Hosakatte Niranjana Murthy et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Physiological, metabolic, and transcriptional effects of biologically-synthesized silver nanoparticles in turnip (Brassica rapa ssp. rapa L.)

(2014) Muthu Thiruvengadam et al.   PROTOPLASMA

Toxicity of aluminium oxide nanoparticles demonstrated using a BY-2 plant cell suspension culture model

(2013) Zuzana Poborilova et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

ROS as key players in plant stress signalling

(2013) A. Baxter et al.   JOURNAL OF EXPERIMENTAL BOTANY

Antimalarial Drug Discovery: From Quinine to the Dream of Eradication

(2013) Adam R. Renslo   ACS Medicinal Chemistry Letters

Xylem- and Phloem-Based Transport of CuO Nanoparticles in Maize (Zea mays L.)

(2012) Zhenyu Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Ca2+-dependent Transcriptional Control of Ca2+Homeostasis

(2012) Jose R. Naranjo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phytotoxicity, accumulation and transport of silver nanoparticles byArabidopsis thaliana

(2012) Jane Geisler-Lee et al.   Nanotoxicology

An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

(2012) Ali Kermanizadeh et al.   Particle and Fibre Toxicology

Accumulation, translocation and impact of TiO2 nanoparticles in wheat (Triticum aestivum spp.): Influence of diameter and crystal phase

(2012) Camille Larue et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Uptake and Distribution of Ultrasmall Anatase TiO2Alizarin Red S Nanoconjugates inArabidopsis thaliana

(2010) Jasmina Kurepa et al.   NANO LETTERS

Nanoparticulate material delivery to plants

(2010) Remya Nair et al.   PLANT SCIENCE

Interactions between engineered nanoparticles (ENPs) and plants: Phytotoxicity, uptake and accumulation

(2010) Xingmao Ma et al.   SCIENCE OF THE TOTAL ENVIRONMENT

In-Vivo Imaging of the Uptake of Upconversion Nanoparticles by Plant Roots

(2009) Anja Hischemöller et al.   Journal of Biomedical Nanotechnology

Evaluation of genotoxic effects of oral exposure to Aluminum oxide nanomaterials in rat bone marrow

(2009) A. Balasubramanyam et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reactive Oxygen Species Are Involved in Brassinosteroid-Induced Stress Tolerance in Cucumber

(2009) X.-J. Xia et al.   PLANT PHYSIOLOGY

Stevioside and related compounds: Therapeutic benefits beyond sweetness

(2008) Varanuj Chatsudthipong et al.   PHARMACOLOGY & THERAPEUTICS