Review
Biochemistry & Molecular Biology
Sergio A. Bernal-Chavez, Maria Luisa Del Prado-Audelo, Isaac H. Caballero-Floran, David M. Giraldo-Gomez, Gabriela Figueroa-Gonzalez, Octavio D. Reyes-Hernandez, Manuel Gonzalez-Del Carmen, Maykel Gonzalez-Torres, Hernan Cortes, Gerardo Leyva-Gomez
Summary: Nanoparticles have great potential for various biomedical applications, but their in vivo use requires sterility. Different sterilization methods can impact the physicochemical properties of nanoparticles.
Review
Chemistry, Medicinal
Simona Petroni, Irene Tagliaro, Carlo Antonini, Massimiliano D'Arienzo, Sara Fernanda Orsini, Joao F. Mano, Virginia Brancato, Joao Borges, Laura Cipolla
Summary: Chitosan is a marine-origin polysaccharide with diverse applications in various sectors. This review provides an overview of chitosan properties, chemical functionalization, and the innovative biomaterials derived from it. The focus is on the preparation of chitosan-based biomaterials and their use in the biomedical field, aiming to inspire further exploration and development of advanced biomedical devices. Selected works from the last 10 years will be considered.
Review
Biochemistry & Molecular Biology
Joana M. M. Domingues, Catarina S. S. Miranda, Natalia C. Homem, Helena P. P. Felgueiras, Joana C. C. Antunes
Summary: The combination of nanoparticles and fibers has led to the development of new strategies for the diagnosis and treatment of diseases. This review focuses on the possibilities and trends of functionalized fibers with nanoparticles, including inorganic and organic nanoparticles, and polymer-based fibers.
Review
Nanoscience & Nanotechnology
Pengxuan Zhao, Youbin Deng, Guangya Xiang, Yani Liu
Summary: Sonodynamic therapy (SDT) using sonosensitizers to generate reactive oxygen species (ROS) has attracted significant interest. With the development of nanotechnology, various nanoparticles (NPs) have been designed to assist sonosensitizers for SDT, showing potential in biomedical applications.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Somu Yadav, Shivangi Chamoli, Piyush Kumar, Pawan Kumar Maurya
Summary: Cerium oxide nanoparticles have wide applications in biomedical fields, but their safety and biocompatibility pose challenges. Polysaccharides can be used as coatings for cerium oxide nanoparticles, affecting their properties. This review explores the impact of biopolymer coatings on size, stability, aggregation, and biocompatibility of cerium oxide nanoparticles, as well as their applications in bone tissue regeneration, liver inflammation, wound healing, and antibacterial and anticancer activities. Biocompatible cerium oxide nanoparticles will enhance their biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Polymer Science
H. P. S. Abdul Khalil, Esam Bashir Yahya, Husnul Azan Tajarudin, Venugopal Balakrishnan, Halimatuddahliana Nasution
Summary: This article introduces the fabrication approach and properties of biopolymeric xerogels for the first time, and discusses their latest applications in drug delivery, wound healing and dressing, tissue scaffolding, and biosensing.
Review
Chemistry, Medicinal
Agnieszka Sidorowicz, Giacomo Fais, Mattia Casula, Massimiliano Borselli, Giuseppe Giannaccare, Antonio Mario Locci, Nicola Lai, Roberto Orru, Giacomo Cao, Alessandro Concas
Summary: Microalgae have been used as a source of useful compounds for food and dietary supplements, as well as for the synthesis of nanoparticles through environmentally friendly routes. The occurrence of global health threats has brought attention to the application of microalgae in medicine. This review discusses the influence of secondary metabolites from microalgae on nanoparticle synthesis as therapeutics, as well as the use of isolated compounds on nanoparticles to combat diseases. However, further research is needed to fully understand the role of microalgae in the human body and translate lab-based research into clinical trials.
Review
Biochemistry & Molecular Biology
Andrey A. Buglak, Marina A. Kapitonova, Yulia L. Vechtomova, Taisiya A. Telegina
Summary: This review focuses on the quantum chemistry and photonics of pterins, providing a comprehensive overview of their electronic structure and potential applications in biomedicine. The study suggests that UV irradiation of pterins can affect enzymatic reactions and that the emission properties of pterins can be used in fluorescence diagnostics. The use of two-photon absorption and metal nanostructures is also proposed for pterin-related infrared therapy and spectroscopy detection of biomarkers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Naeem Kiani, Muhammad Shoaib Butt, Iftikhar Hussain Gul, Mohsin Saleem, Muhammad Irfan, Abrar H. Baluch, Muhammad Aftab Akram, Mohsin Ali Raza
Summary: In this study, the antibacterial properties of Co1-xNixMgxFe2O4 nanoparticles (NPs) against Gram-negative and Gram-positive bacteria were assessed. The Co0.5Ni0.25Mg0.25Fe2O4 NPs exhibited strong antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. These results suggest that the antibacterial properties of NPs have potential applications in hyperthermia, antibacterial treatments, and targeted drug delivery.
Review
Chemistry, Multidisciplinary
Drahomira Holmannova, Pavel Borsky, Tereza Svadlakova, Lenka Borska, Zdenek Fiala
Summary: This review summarizes the current and future applications of carbon nanoparticles in medicine. Carbon nanoparticles, such as graphene, graphene oxide, and carbon nanotubes, have unique physicochemical properties that make them suitable for clinical use. They are mainly used in medical diagnostics, including bioimaging and chemical/metabolite detection. However, their use in therapeutics, regenerative medicine, and vaccine production is still under research due to nanoparticle toxicity concerns. Preclinical studies show great potential for diagnosis and treatment, but caution is needed before their routine clinical use.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Multidisciplinary
Junchi Ma, Yanru Gu, Depeng Ma, Weizhao Lu, Jianfeng Qiu
Summary: This article introduces the development history of aggregation-induced emission (AIE) molecules and recent progress in their applications in the field of biomedicine. AIE-based materials offer significant advantages in in vivo detection and demonstration of biological processes due to their high sensitivity, excellent photostability, and good biocompatibility.
FRONTIERS IN CHEMISTRY
(2022)
Article
Materials Science, Ceramics
Mohamadali Raessi, Hajar Q. Alijani, Farima Foroughi Nematollahi, Roua S. Baty, Gaber El-Saber Batiha, Arif Ullah Khan, Nooshin Hashemi, Siavash Iravani, Iraj Sharifi, Mohammadreza Aflatoonian, Mehrdad Khatami
Summary: The biosynthesis of barium carbonate nanoparticles using plant-mediated synthesis shows promising potential for biomedical applications, especially in cancer therapy, due to their useful medicinal potentials and suitable biocompatibility. The nanostructures were characterized using X-ray diffraction, scanning electron microscopy, and transmission electron microscope, and their toxicity on U87 brain cancer cells was evaluated, showing the prepared nanostructures can be employed for biomedical applications.
CERAMICS INTERNATIONAL
(2021)
Review
Chemistry, Multidisciplinary
Lenitza M. Nieves, Katherine Mossburg, Jessica C. Hsu, Andrew D. A. Maidment, David P. Cormode
Summary: Silver chalcogenide nanoparticles have attracted significant attention for their excellent performance in both electronics and biomedical applications. Recent advancements have shown their potential in various biomedical fields such as bio-imaging and theranostics. The development of different synthetic approaches has further expanded the applications of silver chalcogenide nanoparticles in biomedicine.
Review
Chemistry, Multidisciplinary
Buzuayehu Abebe, H. C. Ananda Murthy
Summary: Colloidal nanocrystals are essential in various applications, with the doping of cations enhancing their properties. The number and distribution of dopants are crucial for protecting the nanocrystals. Instruments like XRD and 4D-STEM can provide information on dopants and obtain high-resolution atomic images.
Review
Chemistry, Physical
Justyna Milan, Klaudia Niemczyk, Malgorzata Kus-Liskiewicz
Summary: Recent advances in the synthesis of metal nanoparticles, particularly gold nanoparticles, have led to their promising applications in biomedical field, such as imaging, treatment, and drug delivery. The unique properties and functionality of gold nanoparticles make them ideal for specific biomedical applications.
